**pharm Test 1 - Lecture 14 - Malaria

Front 1

Malaria drugs either have these 4 leters, or end in these 3

Back 1

quin, ine

Front 2

The 1st drug to be used for malaria was ____A____. While it's disadvantage is ___B____ it does have___C___. It has the ability to __D___.

Back 2

quinine
less potent
won't develop resistance
disrupt replication/transcription

Front 3

Chloroquin is another malaria drug. It works by interfering w/ ____utilization and ____

Back 3

hemoglobin utiliztation
metabolism

Front 4

_____is a drug that works by intetrfering w/ hemoglobin utiilziation and metabolism against malaria

Back 4

chloroquin

Front 5

Primaquin is an anti-malaria drug that is useful in that it inhibits ______. It's use unique in that it_____.

Back 5

respiratory chain of mitochondria
prevents RELAPSE of P. vivax

Front 6

_____ is the anti-malaria drug that inhibits mitochondrial respiratory chain, and prevents the relapse of P. vivax malaria

Back 6

primaquin

Front 7

Pyrimethamine is an anti-malaria drug that is used to treat ______ (specific species) and it works by inhibiting synthesis of _____by blocking_____.

Back 7

P. falciparum
folic acid
dihydrofolate reductase

Front 8

_____ is an anti-malaria drug that is used to treat P. falciparum and it works by inhibiting synthesis of folic acid dihydrofolate reductase

Back 8

Pyrimethamine

Front 9

Coartem is used to treat a specific type of infection of P. falciparum that is _____ and ______.

Back 9

acute
uncomplicated

Front 10

2 drugs used to treat P. falciparum are

Back 10

pyrimethamine and coartem