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82 Cards in this Set
- Front
- Back
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What are the Opiod Agonist(s)
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Morphine - MS Contin
Methadone - Methadose Meperidine - Demerol |
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What is the opiod antagonist?
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Naloxone (Narcan)
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What is the opioid agonist that is an analgesic?
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Nubain - Nalbuphine
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What is in the Salicylate class
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ASA
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What is an antipyretic with no class?
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Acetaminophen (tylenol)
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What is the topical non-opiod analgesic?
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Capsaicin (Zostrix)
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What is the nonopiod analgesic used for joint health?
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Chondroitin
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What is the prostaglandin inhibitor?
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Ketorolac (Toradol)
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What is the Xanthine Oxidase inhibitor?
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Allopurinal (Zyloprim)
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What are the anti-gout medications?
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Allopurinal and Colchicine
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What is the med with the Five HT1 agonist class?
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Imitrex (sumatriptan)
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What is in the alpha adrenergic blockers?
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DHE 45
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What are the 2 benzo's?
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Valium (Diazepam)
Ativan (Lorazepam) |
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What is the benzo antagonist?
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Flumazenil (Romazicon)
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What is BuSpar (Buspirone) used for?
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Anti-anxiety
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What class is zolpidem (ambien) in?
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Sedative/Hypnotic
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What is the herbal anti-anxiety?
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Kava Kava
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What are the 3 anti-psychotics
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Thorazine (Chlorpromazine)
Clozapine (Clozaril) Ziprasidone (Geodon) |
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What are 3 antidepressants?
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Tricyclic (Tofranil)
SSRI (Prozac & Lexapro) MAO inhibitor (Nardil) |
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What is the herbal antidepressant?
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St. John's wort
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What are the patient related variables?
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Age, Weight, Height, Gender, Ethnicity, DNA, Different organs of excretion
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Which drug name is for a chemist or pharmacist?
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Chemical
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Which drug name's ending is very important?
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Generic (Family name)
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Which drug name is based on if people will buy or not?
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Trade name
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When was the Pure Food and Drug Act made and what did it establish?
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1906 - FDA
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Which act scheduled drugs?
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Controlled Substances
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What are the 5 schedules for drugs?
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1 - not approved at all
2 - used medically with high abuse potential 3 - less abuse than 1 or 2 but may lead to dependence 4 - Drugs with some potential for abuse 5 - drugs with moderate controlled substances in them? |
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What schedule are Rohypnol, GHB, Marijuana in?
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1
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What schedule is Codeine, morphine, cocaine in?
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2
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What schedule are steroids in?
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3
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What schedule are the benzodiazepames in?
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4
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What schedule are anti-diarrheal drugs in?
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5
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What is a BBW?
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Black Box Warning - strongest warning from the FDA and often includes prescribing or monitoring information intended to improve the safety of using the drug.
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What is the word used for the strength of drug binding
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Affinity
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What is the word used for the ability of a compound to stimulate the receptor to some action?
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Efficacy
It does what the drug is marketed to do more times than not |
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What occurs when two drugs with similar effects are taken?
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Additive effects
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What occurs when two drugs with different sites or mechanisms of action produce greater effects when taken together?
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Synergism
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What happens when one drug with the metabolism of a second drug may result in intensified effects of the 2nd drug?
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Interference
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What happens when a drug with a strong attraction to protein binding displaces a less tightly bound drug?
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Displacement
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Which are drugs that mimic natural substances that can speed or slow things??
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Agonists
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What inhibits cell function by occupying cell receptor sites?
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Antagonist
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What is the definition of bioavailability?
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the proportion of administered drug that is actually available to produce systemic effects
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What are the 4 phases of pharmacokinetics
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Absorption, Distribution, Metabolism, Excretion
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What are the 5 pregnancy categories?
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A - No risk to fetus
B - No adverse effects on animals C - Only given when absolutely needed. Adverse effects noted D - Definite fetal risks X - Absolute teratogen - NEVER USE |
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What are the "rights" of administration
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Right patient
Right drug Right dose Right route Right time Right nurse Right environment |
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What are the 4 phases of pharmacokinetics?
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Absorption, Distribution, Metabolism, Excretion
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What is the blood or tissue level or the drug for the ability of the drug to affect life processes?
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Bioavailability
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What do the A fibers produce a sensation of?
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Acute pain
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What do the C fibers produce a sensation of?
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Chronic pain
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What are drugs that mimic natural endorphins?
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Opiates
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What is the cholenergic thing? what's it associated with?
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Acetylcholine - memory
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What is the dopaminergic thing? What's it associated with?
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Dopamine - passion, fine motor movements
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What is the GABA-nergic thing?
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GABA - emotion center
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What is the noradrenergic thing? What does it do?
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Noradrenaline - speeds up all transmission
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What is the seratongergic thing? Associated with?
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Seratonin - sleep, mood, happiness, peace
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What are the amino acids associated with neurotransmitters
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Tryptophan and Glutamate
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What is the analgesic prototype??
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Morphine
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What kind of pain is morphine good for?
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Acute - moderate to severe
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What drug produces analgesia, CNS depression, respiratory depression and depressions peristalsis?
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Morphine
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What are the protective reflexes?
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Cough, blink, gag
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What drug has the adverse reactions of:
Respiratory depression, confusion, sedation, hypotension, constipation |
Morphine
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Why wouldn't you give anything for head trauma?
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Could cause vasodilation making it worse
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What is the antidote for morphine?
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Narcan
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What drug is 100x more potent than morphine?
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Fentanyl
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What drug is 10x more potent that morphine?
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Hydromorphone
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What drug is used a lot in obstetrics and for people who can't tolerate morphine?
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Demerol (Meperidine)
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What drug is contraindicated in pregnancy and renal failure b/c it can cause seizures in RF.
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Demerol
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What is the product derived from chili peppers that blocks substance P?
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Capsaicin (Zostrix)
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What is the cancer pain national standard of keeping pain below?
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4
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How is children's pain med dosed?
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Dosed by BSA
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What drug doesn't give you the same pulmonary effects as morphine?
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Hydromorphone (Dilaudid)
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What is given to people who are addicted to opioids. Doesn't produce a high.
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Methodone
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What drug is given orally for chronic pain?
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Ultram
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What drugs are used primarily in obstetrics
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Stadol and Nubain
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What drug causes prostaglandin inhibition
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ASA - aspirin
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Why is aspirin CI in pregnancy?
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Prostaglandins are needed in pregnancy!
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Why don't you give someone with asthma aspirin?
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Aspirin blocks prostaglandins, but makes leukotrienes go crazy. Leukotrienes make asthma worse
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What's the therapeutic range for aspirin for pain/fever
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325-650 mg q4h
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what's the therapeutic range for ASA for RA/OA
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2-6 grams/day
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what's the therapeutic range for ASA for MIA, TIA, stroke
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81-325
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therapeutic range for ASA for rheumatic fever
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5-8g/day
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therapeutic range for ASA for TIA
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1300mg/day
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