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27 Cards in this Set
- Front
- Back
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what is clobestasol?
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local acting corticosteroid - THE MOST POTENT
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what is beclomethasone?
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local acting corticosteroid - high potency
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what is budesonide?
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local acting corticosteroid - potent
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What is fluocinolide?
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local acting corticosteroid - medium potency
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What is desoximetasone?
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local acting corticosteroid - medium potency
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what is fluorometholone?
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local acting corticosteroid - medium potency; OPTICAL ONLY
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what is desonide?
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local acting corticosteroid - low potency
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what is hydrocortisone?
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systemic corticosteroid
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what is prednisone?
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systemic corticosteroid
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What is prednisolone?
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systemic corticosteroid
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what is methylprednisolone?
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systemic corticosteroid
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what is triaminolone?
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systemic corticosteroid
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what is betamethasone?
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systemic corticosteroid
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what is dexamethasone?
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systemic corticosteroid
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how must corticosteroid therapy be stopped?
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it must be slowly discontinued
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what is aminoglutethimid?
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glucocorticoid inhibitor - aromatase inhibitor
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what is ketoconzole?
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glucocorticoid inhibitor - inhibits P450s - inhibits steroid biosynthesis
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what is metyrapone
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glucocorticoid inhibitor - inhibits 11hydroxylation
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what is mifepristone?
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glucocorticoid inhibitor
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when is aminoglutethimid used?
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with metyrapone of keotconazole to reduce steroid secretion in Cushing's due to adrenocortical cancer\; BUT has severe side effects
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when is metyrapone used?
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to diagnostically measure the ability of the pituitary to produce ACTH; has severe adverse effects
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when is mifepristone used?
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used to treat Cushings due to ectopic ACTH production or adrenal carcinoma
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what is deoxycorticosterone or desoxydortociosterone?
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mineralocorticoids - precursor of aldosterone with mineralocorticoid effects
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what is fludrocortisone acetate?
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potent mineralocorticoid with both mineralocorticoid and glucocorticoid activity; used in mineralocorticoid therapy mainly
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what is spironolactone?
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mineralocorticoid antagonist
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when is spironolactone used?
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in primary aldosteronism, to treat hirsutism and as a diuretic
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what are the adverse effects of spironolactone?
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hyperkalemia, cardiac arrhythmias, menstural abnormalities, gynecomastia, sedation, headache, GI disturbances, skin rashes
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