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18 Cards in this Set
- Front
- Back
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amphetamine structure
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similar to NE
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ampetamine mechanism of action
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indirect sympathomimetic amine
causes massive relase of NE DA and 5-HT |
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treatment of amphetamine intox
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nitroprusside or alpha blocker for BP
sedative |
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amphetime use
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hypersomnia
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alternative to amphetamine for hypersomnia
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modafinil
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orlistat
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weight loss drug
pancreatic lipase inhibitor |
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sibutramine
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weight loss druG
inhibits 5-HT and NE reuptake enhances satiety and thermogenesis |
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methylphenidate
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ADHD
related to amphetamine ritalin |
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mechanism of action of cocaine
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blocks uptake of NE, DA, 5-HT
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modafinil
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alternative to amphetime for hypersomnia treatment
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how to allevaite cocaine induced psychosis
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neuroleptics
DA receptor antagonists |
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methylxanthine
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alkaloid in tea, coffee, cocoa
increased alertness respiratory stimulation convulsive potential at high dose |
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mechanism of action of methylxanthine
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competitive inhibition of CNS adenosine A1 and A2 receptors
inhibits PDE and increases cAMP and high dose |
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medical use of methylxanthine
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asthma
apnea |
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examples of methylxanthine
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caffeine, theophylline, theobromine
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nicotine low dose effects
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activate nicotninc receptor subtypes in autonomic ganglia, lungs, airway, and CNS
no NMJ affect |
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nicotine high dose effects
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acts on all nicotinic receptors
depolarizing blockade and receptor denesitization at autonomic ganglia nd NMJ |
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overdose of nicotine
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cardivascular collapse, muscle weakness, respiratory failure
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