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65 Cards in this Set
- Front
- Back
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Drugs that interfere w/ cell wall synthesis
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Pens, Cephalosporin, Vancomycin Bactricin
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Pens are NOT good for
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rickettsia, fungi, viruses ameoba
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Longer duration Pen G
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Benzathine, also prociane pen G
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Drugs that protein synthesis
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Macrolides, Clindamycin, Chlomaphenacol, aminoglycosides, tetracycline
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Give examples of other pens that are excreted by both kidney and liver
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ox's and nafcillin
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2 antibiotics that are inhibited by stomach acid
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Erythromycin, Pen G
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TMT of gonorrheoa
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pens, spectinomycin
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P. Aeruginossa
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CarTiPi aminoglycs
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Legionella
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erythromycin, clarithromycin
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Mycoplasma
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Eryth, claryth and tetra
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Chlamydia
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eryth, claryth, tetra
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H. pylori
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claryth and sometimes tetra
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MRSA
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Vancomycin, linezolid
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C. diff cause=
C diff tmt= |
Clinda
tmt=macrolides |
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__ antibiotic is inhibited by stomach acid and interferes w/ metabolism of other drugs
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Erythromycin
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__ is main side effect of Erythromycin
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GI distress
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__ and __ are alternatives to erythromycin, have less GI sideffects
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Clarthromycin, Azythromycin
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__ antibitotic should not be taken w/ food
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Azithromycin
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__ is like erythromycin but better coverage for mycobact., h. pylori and toxoplasmosis
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Clarithromycin
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Azithromycin is better than clarith for __ and has __ half life
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H. influenzae
2-3 day half life |
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__ antibiotics are broad spectrum and have a wide distribution
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Tetracycline
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Tetracycline is good for infections by __, __ also a few others
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Lyme disease, rickettsiae also mycoplama, chlamydia and h. pylori
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When tetracycline is transported into cell it binds to __
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30 s ribosome
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Antacids block absorption of which antibiotic
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tetracycline
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__ is like tetracyline but has longer half life and gets into tears
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Minocycline
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2 antibiotics that cause vestibular toxicity
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Vancomyin, minocycline
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Tetracycline used to treat GISA
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Tigecycline
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__ is the antibiotic that is ONLY effective against aerobic bact
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Aminoglycosides
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__ antibiotics are bacteriosidal
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Aminoglycosides
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Method of resistance bact build to aminoglycosides is __
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Enzyme metabolism
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__ and__ are antibiotics rapidly excreted unchanged by the kidney
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Pen, aminoglycosides
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Aminoglycosids can be very toxic, name some systems it is toxic to
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Renal toxicity, ototoxicity, neuromuscular toxicity
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__ is an aminoglycoside used to treat TB
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Streptomycin
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__ is an aminoglycoside impt in G(-) infections esp. enterococci
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Gentamycin
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__ is an aminoglycoside that has the broadest spectrum
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Amikacin
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__is a topical aminoglycoside which may be toxic, so only topical or in bowel surgery
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Neomycicn
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__ is an aminoglycoside impt in gonorrhea
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Spectinomycin
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__ binds to same side as macrolides and cholamphenacol so can't be used t/g
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Clindamycin
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Clindamycin is a __ spectrum drug
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Narrow
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__ antibiotis dietributes well into bone and crosses placenta and can affect bact to up to 2 wks after tmt
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Clindamycin
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Name some sideffects clinamycin may cause
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Pseudomembranous colitis, Steven Johnsons, NMJ bockade
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Clindamycin is most useful for __ infections
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Anaerobic
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__ is related to lindamycin and is synergistic w/ aminoglycosides but can cause "red man" syndrome
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Vancomycin
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__ is a topical clindamycin
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Bacitricin
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__ and __ are useful in VREF
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Streptogrammins and Linezolid
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__ is useful only for obligate anaerobes
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Metronidozole
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Metronidazole is useful for __ b/c they contain __
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parasites, amebo, gardia nitroreductase
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__ antibiotic enters CNS and can cause a change in precetion in taste and turn uring re/brown
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Metronidozole
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__ antibiotics should NOT be used w/ alocohol
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Metronidazole, cephalosporins
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__ antibiotics show some x-resistance w/ pens to S. pneumonia and aureus
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Cephalosporins
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2 antibiotics that enter CNS
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metronidazole and cephalosporins
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Cephalosporins can/can't be used in pregnancy
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can
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List some side effects of cephlaosporins
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GI, nephrotoxic, bone marrow supression, antibuse like effect
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1st generation cephs
2nds generation 3rd generation 4th generation |
1st- Good G+, some G-
2nd-inc G- 3rd-best G-, dec G+ 4th good G-, better G+ |
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__ antibiotics should be used in bone infections
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Cephalosporins
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__ needs to be administered w/ cilcestatin IV, and has a boad spectrum and MAY show some x-sensitivity
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Imipinem
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__ is an alternitive b-lactamsthat can be useful for IRP. aeruingosa
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Meropenem
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__ is an alternitive b-lactam that is NOT effective agains anaerobes of G+ but DOES NOT show x-sensitivity
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Aztrenoam
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1st line for TB Acronym
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RESPI
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__ most useful/least expensive drug for TB, can/can't get into CNS, cancan't be used for preg.
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Isonazide
can get into CSF safe for preg |
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__ eliminates dormant/caseous lesions but turns fluid oragne, can/can't be used in preg, many drug interactions
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Rifamfin
can |
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__ prevents development of resistance to rifamfin, can/can't be used in preg
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Pyrazinamide
can't |
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__ is the best tolerated TB drug but can cause eye trouble, can/can't be used for preg, resistance is uncommon
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Ethambutanol
Can |
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When treating TB if have resistance to strepto __ can be used and is better tolerated
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Capreomycin
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__ are the most active agains TB and safe after INH or RIF but have developed more resistance
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Fluoroquinones
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