Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
6 Cards in this Set
- Front
- Back
|
What is selection pressure?
|
Influence exerted by an antibiotic on natural selection to promote killing of susceptible bacteria and allowing survival and multiplication of antibiotic-resistant bacteria.
|
|
|
What are the two genetic mechanisms of drug resistance?
|
1) spontaneous mutation of DNA 2) genetic exachnage
|
|
|
What causes spontaneous mutations and what are the 2 types?
|
Replication error, defect in mismatch pair, spontaneous DNA lesions. 1) deletion/insertion alters reading frame 2)base substitution - missense or nonsense
|
|
|
What are the four modes of genetic exchange?
|
1) transformation 2) transduction 3) conjugation 4) transpositional recombination
|
|
|
What is transformation?
|
When genes are transferred as naked DNA
|
|
|
What is transduction?
|
When DNA is transferred through a bacteriophage. (lytic and lysogenic cycle)
|
