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16 Cards in this Set
- Front
- Back
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Lysergic Acid Diethylamide has what effect on the brain?
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Potent hallucinogen 1microgram/kg
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What receptor does Lysergic Acid Diethylamide act on?
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LSD acts as a full or partial agonist at the 5HT2 receptor
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What receptor does buspirone act on?
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5HT1A receptor
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What is buspirone used for
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An antianxiety agent
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What is sumatriptan used for?
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Used in the treatment of migrane headaches
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What receptors is sumatriptan specific for?
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Sumatriptan is an agonist at the 5-HT1D receptor on cerebral blood vessels.
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What are some side effects of sumatriptan?
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Nausea vomitting, angina, dizziness, flushing
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What type of medication is fluoxetine?
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Fluoxetine is a serotonin specific reuptake inhibitor. SSRI. This blocks the active reuptake of serotonin into neurons, increasing the amount of serotonin at the synapse.
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What conditions is fluoxetine used in?
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Affective disorders, obsessive compulsive disorder, panic attacks.
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What type of medication is phenelzine?
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A monoamine oxidase inhibitor. Blocks the metabolism of serotonin, norepinephrine, and dopamine.
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What is the major side effect of phenelzine?
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because phenelzine is a MAO, it can lead to increased tyramine levels. This can cause a hypertensive crisis.
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What receptor is cyproheptadine specific for?
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Cyproheptadine is a 5HT2 receptor antagonist. It is also a histamine H1 antagonist.
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What is cyproheptadine used for?
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Cyproheptadine is used for the treatment of skin allergies, pruritus and urticaria (hives)
It is also used in the treatment of carcinoid |
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Ondansetron works on what receptor?
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5HT3 receptor antagonist = ondansetron.
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What is Ondansetron used in?
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Tx of nausea/vomitting during chemotherapy, acting at both GI and brain receptors.
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Alosetron acts on what receptor. How does alosteron work?
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5HT3 antagonist. IT is used to treat women with diarrhea predominant IBS that do not respond to conventional therapy. Can produce very severe GI effects.
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