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5 Cards in this Set
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- Back
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Diuretics - Name the site of action:
- thiazides? - loop diuretics? - mannitol? - K+ sparing diuretics? - acetazolamide? - ADH antagonist? |
- thiazides? --> DCT
- loop diuretics? --> thick ascending limb of LOH - mannitol? --> PCT - K+ sparing diuretics? --> CT - acetazolamide? --> PCT - ADH antagonist? --> CD |
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Indications for mannitol?
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Osmotic diuretic used for drug OD, decreases ICP/IOP
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Indications for acetazolamide?
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NaHCO3- inhibitor that causes self-limited NaHCO3 diuresis and decrease total body HCO3- stores.
Used for glaucoma, urinary alkalinization, metabolic alkalosis, altitude sickness, pseudotumor cerebri. |
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Diuretic that can result in hyperchloremic metabolic acidosis, paresthesia, NH3 toxicity, sulfa allergy?
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Acetazolamide. "ACIDazolamide causes ACIDdosis"
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Indications for Furosemide?
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Sulfonamide loop diuretic that inhibits Na+/K+/2Cl- cotransport in the TAL of LOH --> prevent urine from concentrating
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