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9 Cards in this Set
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Mannitol
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Osmotic diuretic
use: shock, drug OD, decreases intracranial/intraocular pressure toxicity: pulm edema, dehydration. contraind: anuria, CHF |
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Acetazolamide
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Carbonic anhydrase inhibitor (reduces body's HCO3-)
use: glaucoma, urinary alkalinazation, met. alk, altitude sickness tox: hyperchloremic met acidosis, neuropathy, NH3 toxicity, sulfa allergy |
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Furosemide
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sulfonamide loop diuretic (inhibits Na/K/2Cl cotransporter in thick ascending limb). Increases Ca excretion
use: edematous states, HTN, hypercalcemia tox: ototoxic, hypokalemia, dehydration, allergy to sulfa, nephritis, gout |
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Ethacrynic acid
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Phenoxyacetic acid derivative.
Same MOA as furosemide, but NOT a sulfa Use: diuresis Tox: sim. to lasix, but can be used in hyperuricemia, acute gout. |
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HCTZ
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inhibits NaCl reabsorption in early distal tubule. decreases Ca excretion.
Use: HTN, CHF, idiopathic hypercalciuria, nephrogenic DI Tox: hypokalemic met alk, hyponatremia, hyper-lipid/uricemia/calcium. sulfa allergy |
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Spironolactone
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Competitive aldosterone receptor antagonist in collecting tubule.
use: hyperaldosteronism, K depletion, CHF Tox: hyperK, endocrine (gynecomastia, antiandrogen) |
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Triamterene
Amiloride Eplerenone |
block Na+ channels in collecting tubule
use: hyperaldosterone, K depletion, CHF Tox: hyperK |
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Captopril
enalapril lisinopril |
ACE inhibitor, reduces angiotensin II, prevents bradykinin inactivation
use: HTN, CHF, diabetic renal dz. tox: Cough, Angioedema, Proteinuria, Taste changes, Hypotension, Pregnancy problems, Rash, increased Renin, lower angiotensin II. CAPTOPRIL. hyperkalemia. |
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Losartan
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Angiotensin II receptor antagonist
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