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37 Cards in this Set

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Bethanechol
MOA: cholinomimetic; activates bowel/bladder sm. muscle
Use: postop/neurogenic ileus/urinary retention
Carbachol
MOA: cholinomimetic
Use: Glaucoma pupillary contraction, releases IOP
Pilocarpine
MOA: cholinomimetic; contracts ciliary muscle, pupillary sphincter, AChE resistant
use: stimulates sweat, tears, saliva; glaucoma emergency
Methacholine
MOA: cholinomimetic; stimulates airway muscarinic receptors
Neostigmine
MOA: anticholinesterase; NO CNS
use: postop/neurogenic ileus/urinary retention; myasthenia, reverse NMJ block
Pyridostigmine
MOA: anticholinesterase; NO CNS
use: myasthenia gravis (long acting)
Edrophonium
MOA: anticholinesterase
use: dx of myasthenia gravis (short-acting)
Physostigmine
MOA: anticholinesterase; crosses BBB
Use: Glacuoma, atropine OD
Echothiophate
MOA: Anticholinesterase
Use: Glaucoma
Atropine
Homatropine
Tropicamide
MOA: muscarinic antagonist
use: causes mydriasis/cycloplegia
Benztropine
MOA: muscarinic antagonist in CNS
Use: parkinson's
Scopolamine
MOA: muscarinic antagonist in CNS
Use: motion sickness
Ipratropium
MOA: muscarinic antagonist in respiratory
Use: asthma, COPD
Oxybutynin
Glyocpyrrolate
MOA: muscarinic antagonist in GU
use: reduces urgency (mild cystitis); reduce bladder spasm
Methscopolamine
Pirenzepine
propantheline
MOA: muscarinic antagonist in GI
Use: PUD
Atropine
MOA: muscarinic antagonist
Side effects: Hot as hare, Dry as bone, Red as beet, Blind as bat, Mad as hatter
Hexamethonium
MOA: nicotinic antagonist
Use: ganglionic blocker; can prevent vagal reflex responses (i.e., to NE)
tox: orthostatic hypotension, blurred vision, constipation, sexual dysfunction
Epinephrine
MOA: alpha 1,2; beta 1,2 agonist
NE
MOA: alpha 1, alpha 2 >> beta 1
use: hypotension (but decreases renal perfusion)
Isoproterenol
MOA: beta 1 and beta 2 agonist
use: AV block
Dopamine
MOA: D1, D2 > beta > alpha (inotrope and chronotrope)
use: shock (increases renal perfusion through D1), heart failure
Dobutamine
MOA: beta1 > beta2; inotrope (NOT chronotrope)
Use: shock, heart failure, stress test
Phenylephrine
MOA: alpha1 > alpha2
use: pupillary dilation, vasoconstriction, nasal decongestion
Albuterol
Terbutaline
MOA: beta 2 >beta1
Use: albuteral for asthma; terbutaline for premature uterine contractions (beta2)
Ritodrine
MOA: beta 2
Use: reduces premature uterine contractions
Amphetamine
MOA: releases stored catecholamines
use: narcolepsy, obesity, ADD
Ephedrine
MOA: releases stored catecholamines
use: nasal decongestion, incontinence, hypotension
Cocaine
MOA: uptake inhibitor of catecholamines
use: vasoconstriction, local anesthesia
Clonidine
alpha-methyldopa
MOA: central alpha2-agonist (decreases adrenergic outflow)
use: hypertension (esp. with renal disease b/c no decrease in blood flow to kidney)
beta-2 agonists
metaproterenol
albuterol
salmeterol
terbutaline
Phenoxybenzamine (irrevers)
Phentolamine (revers)
MOA: nonselective alpha-blocker
use: pheochromocytoma
tox: orthostatic hypotension, reflex tachy
prazosin
terazosin
doxazosin
MOA: alpha1 blocker
use: HTN, BPH
tox: 1st dose orthostatic hypotension, dizziness, HA
Mirtazapine
MOA: alpha2 blocker
use: depression
tox: sedation, increases cholesterol/appetite
Propranolol
Timolol
Nadolol
Pindolol
Labetalol
MOA: nonselective beta-1 and beta-2 blocker
Acebutolol
Betaxolol
Esmolol
Atenolol
Metoprolol
MOA: beta-1 > beta-2 blocker
Carvedilol
Labetolol
MOA: nonselective alpha AND beta blocker
Pindolol
Acebutolol
MOA: partial beta-agonists