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37 Cards in this Set
- Front
- Back
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Bethanechol
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MOA: cholinomimetic; activates bowel/bladder sm. muscle
Use: postop/neurogenic ileus/urinary retention |
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Carbachol
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MOA: cholinomimetic
Use: Glaucoma pupillary contraction, releases IOP |
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Pilocarpine
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MOA: cholinomimetic; contracts ciliary muscle, pupillary sphincter, AChE resistant
use: stimulates sweat, tears, saliva; glaucoma emergency |
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Methacholine
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MOA: cholinomimetic; stimulates airway muscarinic receptors
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Neostigmine
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MOA: anticholinesterase; NO CNS
use: postop/neurogenic ileus/urinary retention; myasthenia, reverse NMJ block |
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Pyridostigmine
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MOA: anticholinesterase; NO CNS
use: myasthenia gravis (long acting) |
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Edrophonium
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MOA: anticholinesterase
use: dx of myasthenia gravis (short-acting) |
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Physostigmine
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MOA: anticholinesterase; crosses BBB
Use: Glacuoma, atropine OD |
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Echothiophate
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MOA: Anticholinesterase
Use: Glaucoma |
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Atropine
Homatropine Tropicamide |
MOA: muscarinic antagonist
use: causes mydriasis/cycloplegia |
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Benztropine
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MOA: muscarinic antagonist in CNS
Use: parkinson's |
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Scopolamine
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MOA: muscarinic antagonist in CNS
Use: motion sickness |
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Ipratropium
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MOA: muscarinic antagonist in respiratory
Use: asthma, COPD |
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Oxybutynin
Glyocpyrrolate |
MOA: muscarinic antagonist in GU
use: reduces urgency (mild cystitis); reduce bladder spasm |
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Methscopolamine
Pirenzepine propantheline |
MOA: muscarinic antagonist in GI
Use: PUD |
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Atropine
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MOA: muscarinic antagonist
Side effects: Hot as hare, Dry as bone, Red as beet, Blind as bat, Mad as hatter |
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Hexamethonium
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MOA: nicotinic antagonist
Use: ganglionic blocker; can prevent vagal reflex responses (i.e., to NE) tox: orthostatic hypotension, blurred vision, constipation, sexual dysfunction |
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Epinephrine
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MOA: alpha 1,2; beta 1,2 agonist
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NE
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MOA: alpha 1, alpha 2 >> beta 1
use: hypotension (but decreases renal perfusion) |
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Isoproterenol
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MOA: beta 1 and beta 2 agonist
use: AV block |
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Dopamine
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MOA: D1, D2 > beta > alpha (inotrope and chronotrope)
use: shock (increases renal perfusion through D1), heart failure |
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Dobutamine
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MOA: beta1 > beta2; inotrope (NOT chronotrope)
Use: shock, heart failure, stress test |
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Phenylephrine
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MOA: alpha1 > alpha2
use: pupillary dilation, vasoconstriction, nasal decongestion |
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Albuterol
Terbutaline |
MOA: beta 2 >beta1
Use: albuteral for asthma; terbutaline for premature uterine contractions (beta2) |
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Ritodrine
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MOA: beta 2
Use: reduces premature uterine contractions |
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Amphetamine
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MOA: releases stored catecholamines
use: narcolepsy, obesity, ADD |
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Ephedrine
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MOA: releases stored catecholamines
use: nasal decongestion, incontinence, hypotension |
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Cocaine
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MOA: uptake inhibitor of catecholamines
use: vasoconstriction, local anesthesia |
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Clonidine
alpha-methyldopa |
MOA: central alpha2-agonist (decreases adrenergic outflow)
use: hypertension (esp. with renal disease b/c no decrease in blood flow to kidney) |
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beta-2 agonists
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metaproterenol
albuterol salmeterol terbutaline |
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Phenoxybenzamine (irrevers)
Phentolamine (revers) |
MOA: nonselective alpha-blocker
use: pheochromocytoma tox: orthostatic hypotension, reflex tachy |
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prazosin
terazosin doxazosin |
MOA: alpha1 blocker
use: HTN, BPH tox: 1st dose orthostatic hypotension, dizziness, HA |
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Mirtazapine
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MOA: alpha2 blocker
use: depression tox: sedation, increases cholesterol/appetite |
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Propranolol
Timolol Nadolol Pindolol Labetalol |
MOA: nonselective beta-1 and beta-2 blocker
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Acebutolol
Betaxolol Esmolol Atenolol Metoprolol |
MOA: beta-1 > beta-2 blocker
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Carvedilol
Labetolol |
MOA: nonselective alpha AND beta blocker
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Pindolol
Acebutolol |
MOA: partial beta-agonists
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