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49 Cards in this Set

  • Front
  • Back

Classifications of medicines that can be used in treatment of anxiety disorders (3)

Antidepressants, Benzodiazepines, Barbiturates

Neurotransmitters associated w/ depression/anxiety

Serotonon -Feelings of wellness


Norepinepherine - Affects Amygdala


Dopamine - Reward driving learning


SSRI (5)

Lexapro


Zoloft


Paxil


Celexa


Prozac

Tricyclic AntiDepressants(4)

Nortripyline (Pamelor)


Amitriptyline


Imipramine


Doxepin


MAOI (3)

Nardil


Parnate


Marplan


How do SSRI's work -

Sustained Serotonin Reuptake Inhibitors


Slows reuptake of seratonin, flooding next nerve w/ seratonin


Seratonin Syndrome

Agitation, dihhrea, heavy sweating, fever, hyperreflexive, high fever, shivering, tremors, ataxia


How do tricyclic antidepressants work?

Blocks seratonin and norepi (-line)


Anticholergic and antihistamine effects. Direct alpha 1 andrenergic blockade, blockade of fast sodium channels in mycardial cells

Drug of choice for tricyclic OD

Sodium bicarb - 2 postulated theraputic effects


tricyclics are protein bound and become less bound in more aciditic conditions. Sodium helps to reverse the Na blocking effects of TCA

Tyramine Containing Food and why they're important to know

Tyramine + MAO-i can cause a hypertensive crisis



Aged cheese,sour cream, yogurt


Aged pickled or smoked meats


Yeast extracts


Beer


Red wine


avocados


sauerkraut


ginseng

S/S of hypertensive MAO-i crisis

Fever, tachycardia, generalize muscle rigidity, tachypnea, metablic acidosis, hypoxemia, hypercapnia

What is the antidote medication for a benzodiazepine OD?

Flumazenil

What is the mainstay drug for bipolar disorder?

Lithium

Other drugs for bipolar (also anti-seizure)

Valproic Acid (Depakote)
Carbamazepine (Tegretol)


Lamictal

What is Gabapentin (Neurontin)?

anticonvulsant and analgesic

What neurotransmitter fosters symptoms of schizophrenia? Too much or too little?

Too much dopamine


Antipsychotic Drugs are also referred to as ...

"Neuroleptics"

Define Akathisia

movement disorder characterized by restlessness, older antipsychotics can cause akathisa

What is tardive dyskinesia?

Disorder resulting in involuntary, often repetitive motions

What is the treatment for antipsychotic dystonia?

benedryl (diphenhydramine) - anticholinergic and antiparkinsonian effects used to treat dystonic reactions caused by antipsychotic


TYPICAL v ATYPICAL Antipsychotics

TYPICAL (Dopamine) - Haldol, droperidol, mellaril, prolixin, stelazine, thorazine



Atypical (dopamine, serotonin) - Risperdal, Ability, Zyprexa, Seroquel

Somatic V Visceral Pain

Both nociceptive pain


Somatic - Sharp, localized (uusally muscular)


Viscreal Pain - dull, throbbing, aching "organ pain"

Qualitites of neuropathic pain

Injury to nerves - Burning, shooting, numb

Treatment for opiod OD w/respiratory compromise

naloxone HCL (Narcan)

What is Buprenorphine (Suboxone, Buprenex)

Used to tread opiod addictions. . Mixed agonist/antagonist opioid receptors

What is methadone used for ?

Narcotic substitute, treatment of opiod addictions

Biggest concern w/Acetaminophen overdose?

Hepatic damage, renal failure

Biggest concern w ASA OD

Metabolic acidosis

Parkinsons Disease is caused by a *LACK* of ...?

Dopamine

Trigeminal neuraligia - Define? Often seen w/?

Multiple Sclerosis. Chronic pain, myokymia

Which five conditions are treated w diuretics?

HTN, Heart Failure, Kidney Failure,


Liver failure and cirrhosis, pulmonary edema

IM / SC Needles / Amounts Absorbed

IM Delt 2mg, butt 5mg 22-25ga 1-1.5"



SC 23-25g, 5/8th"

SSRI Anti-Depressants(5)

Lexapro, Zoloft, Paxil, Celexa, Prozac



Causes lots of serotonin in junctions

Tricyclic Antidepressants (4)

Nortripyline


Amitryptyline


Imipramine


Doxepin



Anticholiergic, A1 blocker, sodium channel blocker (sodium channel=most lethal s/e)

MAOI (3)

Nardil, Parnate, Marplan (Anti-Anxiety)

Benzodiazepine (6)

Ativan, Xanax, Librium, Restoril, Fulazapam, Prosom



Increase GABA, inhibits cellular excitement

Barbiturates(2)

Phenobarbitol, Seconarbital (Increase GABA)

Anti-Convulsants, Bi-Polar (5)

keppra, Lamictal, Dilantin, Valproic acid (Depakote), Tegretol

SNRI Anti-Depressants (2)

Pristiq, Cymbalta

Loop Diuertics

Bumex, Lasix (black Na reabsorption)

ACE Inhibitors

Accupril, Ramipril, Catporil

Calcium Channel Blockers (5)

Norvasc, Cardene, Procardia, Cardezem, Verapamil



Hypertension/Arythmias

Beta Blockers

-olol. Metoprolol, acebutolol, labetalol

Cardiac Glycoside

Digoxin (ionotropic affect)

Anti-coagulants(2)

Warfarin, Heparin

Anti-Cholinergic (asthma)

Spiriva and Atrovent

Antacids

Tagament, Pepcid, Zantac

Diabetic Meds

Diabinese, Glipizide, Glyburide (Stimulate B to create insulin)


Metformin - helps use insulin better


actos and avandia body makes less sugar


AntiPhosphdiesterase - ED meds

-fil


tadalafil, Vardenafil, Sildenafil