Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
50 Cards in this Set
- Front
- Back
|
Methimzole
|
Antithyroid
-inhibits synthesis of thyroid hormone by accommulation -hyperthyroidism (prior to surgery or radiotherapy) -SE: hypothyroidism, arthralgia, pancytopenia |
|
|
Propylthiouracil
|
Antithyroid
-interferes with use of iodine: blocking synthesis of T3 and T4 -Hyperthyroidism -SE: HA, vertigo, loss of taste |
|
|
Potassium Iodine
|
Antithyroid
-saturates the thyroid gland, inhibits hyperplastic thyroid gland -hyperthyroidism -SE: GI, irregular HR |
|
|
Levothryoxine
|
Thyroid
-synthetic form of throxine (t4), mimics activity of thyroid hormone -hypothyroidism -SE: osteroporosis, arrhthmia |
|
|
Liothronin
|
Thryoid
-hypothyroidism |
|
|
Liotrex
|
Thryoid
-T4 & T3 -hypothryoidism |
|
|
Humalog (lispro)
|
Diabetes (rapid acting)
-increases peripheral uptake (SkM, fat tissue), decreases glycogenolysis -Diabetes Melitus -hypoglycemia, allergy, lipodystrophy |
|
|
Humalin R
|
Diabetes (short acting)
-highly soluble (onset 30-60min, duration 5-7 hours) -emergent diabetic ketoacidosis or coma, use in comb with other insulins -SE: hypoglycemia |
|
|
Humalin N
|
Diabetes (immediate acting)
-onset: 1-2 hours, duration: 10-16 hours -Diabetes Melitus |
|
|
Lantus
|
Diabetes (long acting)
-decrease glycogenolysis (onset: 2-4 hours, duration: 24+ hours) -Diabetes Melitus -SE: hypoglycemia, itch, rash, hypokalemia, lipodystrophy |
|
|
Chlorpropamine
|
Diabetes: 1st gen-sulfonylurea
-stimulates insulin release, inhibits glucose synthesis from AA/ FA, increase number of insulin receptors -mild to moderate DM2 -SE: hypoglycemia, blur, GI |
|
|
Tobutamide
|
Diabetes: 1st gen-sulfonylurea
-stimulates insulin release, inhibits glucose synthesis from AA/ FA, increase number of insulin receptors -mild to moderate DM2 -SE: hypoglycemia, blur, GI |
|
|
Glipizide
|
Diabetes: 2nd gen-sulfonylurea
-stimulates insulin release, inhibits glucose synthesis from AA/ FA, increase number of insulin receptors -mild to moderate DM2 -SE: hypoglycemia, blur, GI |
|
|
Glyburide
|
Diabetes: 2nd gen-sulfonylurea
-stimulates insulin release, inhibits glucose synthesis from AA/ FA, increase number of insulin receptors -mild to moderate DM2 -SE: hypoglycemia, blur, GI |
|
|
Metformin
|
Diabetes: biguanide
-promote glucose uptake by increasing insulin receptor binding; decrease gluconeogenesis, slow glucose absorption, increase glucose removal -DM2 (keeps blood glucose from rising or falling too fast) -SE: anorexia, GI |
|
|
Pioglitazone
|
Diabetes: Thiazolidinedione
-improves cell sensitivity to insulin by stimulating receptors in SkM, liver, fat cells -adjuncts to diet in DM2 -SE: hepatoxicity, edema, anemia |
|
|
Rosiglitazone
|
Diabetes: Thiazolidinedione
-improves cell sensitivity to insulin by stimulating receptors in SkM, liver, fat cells -adjuncts to diet in DM2 -SE: hepatoxicity, edema, anemia |
|
|
Acarbose
|
Diabetes: alpha glucosidase inhibitor
-inhibits absorption of sugar from GI -can be used in combo with sulfornylura -SE: GI, gas, hypogylcemia |
|
|
Miglitol
|
Diabetes: alpha glucosidase inhibitor
-inhibits absorption of sugar from GI -can be used in combo with sulfornylura -SE: GI, gas, hypogylcemia |
|
|
Pramlintide Acetate
|
Diabetes: other
|
|
|
Exenatide
|
Diabetes: other
|
|
|
Sitagliptin
|
Diabetes: other
|
|
|
Dexamethaxone
|
Corticosteroids
-antiinflammitory, immunosuppresive -Addison's disease, congenital adrenal hyperplasia; rheumatic, inflammatory, allergic, neoplastic, other; Topical: pruritis, psoriasis, eczema -SE: insomnia, behavioral changes, acute peptic ulcer; Cushing's, acne; osteoporosis, diabetes, delayed healing, cataracts, glaucoma |
|
|
Hydrocortisone
|
Corticosteroids
-antiinflammitory, immunosuppresive -Addison's disease, congenital adrenal hyperplasia; rheumatic, inflammatory, allergic, neoplastic, other; Topical: pruritis, psoriasis, eczema -SE: insomnia, behavioral changes, acute peptic ulcer; Cushing's, acne; osteoporosis, diabetes, delayed healing, cataracts, glaucoma |
|
|
Prednisolone
|
Corticosteroids
-antiinflammitory, immunosuppresive -Addison's disease, congenital adrenal hyperplasia; rheumatic, inflammatory, allergic, neoplastic, other; Topical: pruritis, psoriasis, eczema -SE: insomnia, behavioral changes, acute peptic ulcer; Cushing's, acne; osteoporosis, diabetes, delayed healing, cataracts, glaucoma |
|
|
Prednisone
|
Corticosteroids
-antiinflammitory, immunosuppresive -Addison's disease, congenital adrenal hyperplasia; rheumatic, inflammatory, allergic, neoplastic, other; Topical: pruritis, psoriasis, eczema -SE: insomnia, behavioral changes, acute peptic ulcer; Cushing's, acne; osteoporosis, diabetes, delayed healing, cataracts, glaucoma |
|
|
Triamcinolone
|
Corticosteroids
-antiinflammitory, immunosuppresive -Addison's disease, congenital adrenal hyperplasia; rheumatic, inflammatory, allergic, neoplastic, other; Topical: pruritis, psoriasis, eczema -SE: insomnia, behavioral changes, acute peptic ulcer; Cushing's, acne; osteoporosis, diabetes, delayed healing, cataracts, glaucoma |
|
|
Aminoglutethimide
|
Cushing's disease
-biosynthetic inhibitor |
|
|
Ketoconazole
|
Cushing's disease
-biosynthetic inhibitor -decrease testosterone production |
|
|
Mifepristone
|
Cushing's disease
-steroid receptor antagist |
|
|
Estradiol
|
Estrogen agonist
-stimulate DNA and RNA synthesis --replacement estrogen therapy, osteoporosis, pallative therapy, abnormal bleeding, atrophic -SE: anorexia, HA, changes in libido, feminization |
|
|
Estrone
|
Estrogen agonist
-stimulate DNA and RNA synthesis --replacement estrogen therapy, osteoporosis, pallative therapy, abnormal bleeding, atrophic -SE: anorexia, HA, changes in libido, feminization |
|
|
Estriol
|
Estrogen agonist
-stimulate DNA and RNA synthesis --replacement estrogen therapy, osteoporosis, pallative therapy, abnormal bleeding, atrophic -SE: anorexia, HA, changes in libido, feminization |
|
|
Ethinyl Estradiol
|
Steroidal Estrogen
-estrogen agonist -used in combination with oral contraceptives |
|
|
Mestranol
|
Steroidal Estrogen
-estrogen agonist -used in combination with oral contraceptives |
|
|
Raloxifene
|
Non-steroidal estrogen
-selective estrogen receptor modulator (antagonist) -treatment and prevention of osteoporosis |
|
|
Tamoxifen
|
Non-steroidal estrogen
-selective estrogen receptor modulator (antagonist) -treatment and prevention of breast cancer |
|
|
Clomiphene
|
Non-steroidal estrogen
-selective estrogen receptor modulator (antagonist) -induces ovulation |
|
|
Hydrocyprogesterone
|
Progestin
-transforms endometrium, suppresses gonadotropin, promote mammary gland development, increases ovulation -secondary amenorrhea, endometriosos, prementral syndrome -SE: vaginal candidiasis, chloasma, depression, changes in vision, ptosis |
|
|
Megastrol
|
Progestin
-transforms endometrium, suppresses gonadotropin, promote mammary gland development, increases ovulation -secondary amenorrhea, endometriosos, prementral syndrome -SE: vaginal candidiasis, chloasma, depression, changes in vision, ptosis |
|
|
Norethindrone
|
Progestin
-transforms endometrium, suppresses gonadotropin, promote mammary gland development, increases ovulation -secondary amenorrhea, endometriosos, prementral syndrome, oral contraception -SE: vaginal candidiasis, chloasma, depression, changes in vision, ptosis |
|
|
Aminoglutethimde
|
Aromatase inhibitor
-treats cancer |
|
|
Mifepristone
|
Contragestational agent
-anti-progestin -contragestation |
|
|
Methyltestosterone
|
Androgen
-anabolic activity -correct hypogonadism, increase sperm production, cryptochidism, breast cancer, endometriosis, postpartum breast enlargement, fibrocystic breast disorder -SE: insomnia, excitation, GI, increases libido |
|
|
Nandrolene
|
Androgen
-anabolic activity -correct hypogonadism, increase sperm production, cryptochidism, breast cancer, endometriosis, postpartum breast enlargement, fibrocystic breast disorder -SE: insomnia, excitation, GI, increases libido |
|
|
Stanozolol
|
Androgen
-anabolic activity -correct hypogonadism, increase sperm production, cryptochidism, breast cancer, endometriosis, postpartum breast enlargement, fibrocystic breast disorder -SE: insomnia, excitation, GI, increases libido |
|
|
Spinorolactone
|
anti-androgens
-reduce activity of cytochome P450 in testes |
|
|
Flutamide
|
androgen antagonist
-anatagonize androgen receptors |
|
|
Finasteride
|
Anti-androgens
-reduces prostate dihydrotestosterone -benign prostatic hyperplasis- decreases prostate size |
|
|
Dutasteride
|
Anti-androgen
-competitive inhibitor or 5 alpha reductase |
