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37 Cards in this Set
- Front
- Back
- 3rd side (hint)
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who is affected more by autoimmune diseases?
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Women
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What is a strong immune reaction to a drug that causes autoimmune?
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Hypersensitivity
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What are the two drug categories of immuno-drugs
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Immunosuppressinve and immunostimulatory
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When do you take immunosuprresive drugs
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Transports
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What are the immunosuprressive drugs
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Azathiprine, cyclophosphamide, methotrexate
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What suppresses drug downregulates immune response in MS?
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Glatiramer
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What are most of the immunostimulatory drugs?
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Human cytokines
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What is innate immunity permormed by in bacterial resistance?
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Complement and phagocytic cells
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What is innate immunity for viral?
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IFN made by fibrolblasts inhibit replication and activate killer cells
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What are the divisions of acquire immunity
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Humoral TH2 (B cells that produce Ab) and Cell-mediated TH1 (T cells that kill invading organism)
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What do corticosteroids do?
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Decrease IL-1 expression, and decrease phagocytosis of virus-infected cells.
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Where are corticosteroids made, and what are they made of?
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Made in adrena medulla, made from cholesterol
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What kills DNA?
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Cyclophosphamide
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What drug interferes with folic acid and purine synthesis
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Azathioprine methotrexate
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What drug inhibits t and b lymphocyte proliferation
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MMF
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How
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How do Calcineurin inhibitors work?
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Downregulate immune response by inhibiting IL-2 production, also inhibit B and T cell activation
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What does an mAb do
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Cloned antibodies that a human cell will recgonize when bound and take whatever it is attached to away.
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How are colony stimulating factors made
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Bacteria activate Macrophage and T cells to make CSF. CSF stimulate production of Macrophages and neutrophils in Bone, phagocytosize bacteria.
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What is the immunosuppres mAB
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muromonab CD3
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What is immunosuppresive MAB
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Iniximab
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what is the anti-allergy mAb
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Omalizumab
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What is the immunodulatory mAb
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interferon=B1b
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Wh
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What is the immunostimulatory mAb
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interferon-a2A
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What is the growth factor mAb
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pegfilgrastimin
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When is cyclophosphamide administered?
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severmanifestations of autoimmune- many toxiciies, kill sperm
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When are GC used
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topical and graft rejections
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What is Azathioprine used for
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PRevent Kidney recection
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What is MMF used for
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Prophylaxis against renal transplant rejection
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What is methotrexate used for
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rHa and psoriasis
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What is Tacrolimu used for
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Liver transplants
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WWhen is Rapamycin used
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Prevent of acute organ rejection
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SE of Cyclophosphamide
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Bone marrow suppression
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SE of Methotrexate
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Liver abnormal
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Azathioprine
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Bone Marrow suppression
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MMF
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Neutropenia
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SE of Cyclopsporine
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Nephro
Hyper Neuro |
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What are the four histamine receptors and where are they?
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H! (everywhere) H2 (Stomach) and H3 (brain)
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