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142 Cards in this Set
- Front
- Back
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Sulfadiazine/Sulfamethoxazole/Sulfasalazine Class?
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Antibiotic
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Sulfadiazine/Sulfamethoxazole/Sulfasalazine Group?
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Sulfanamides
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Sulfadiazine/Sulfamethoxazole/Sulfasalazine Mechanism?
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Inhibit folic acid synthesis (paraaminobenzoic acid, PABA, precursor)
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Sulfadiazine/Sulfamethoxazole/Sulfasalazine Effect?
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Bacteriostatic
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SMZ/TMP Class?
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Antibiotic
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SMZ/TMP Grouping?
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Sulfonamides
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SMZ/TMP Mechanism?
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Inhibits conversion of dihydrofolate to folinic acid
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SMZ/TMP Effect?
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Bacteriostatic
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Penicillin G/Penicillin V Class?
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Antibiotic
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Penicillin G/Penicillin V Group?
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Natural penicillins
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Penicillin G/Penicillin V Mechanism?
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Interferes with the synthesis of peptidoglycans, which inhibits synthesis of bacterial cell wall
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Penicillin G/Penicillin V Use?
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UTI, gonorrhea, syphilis, meningitis, pneumonia
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Nafcillin/Cloxacillin/Oxacillin Class?
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Antibiotic
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Nafcillin/Cloxacillin/Oxacillin Group?
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Penicillinase-resistant (Beta lactamase resistant)
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Nafcillin/Cloxacillin/Oxacillin Mechanism?
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Interferes with the synthesis of peptidoglycans, which inhibits synthesis of bacterial cell wall
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Nafcillin/Cloxacillin/Oxacillin Use?
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UTI, gonorrhea, syphilis, meningitis, pneumonia
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Amoxicillin (Augmentin), Ampicillin (Unasyn) Class?
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Antibiotic
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Amoxicillin (Augmentin), Ampicillin (Unasyn) Group?
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Aminopenicillin
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Amoxicillin (Augmentin), Ampicillin (Unasyn) Mechanism?
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Interfere with the synthesis of peptidoglycans, which inhibits synthesis of bacterial cell wall
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Amoxicillin (Augmentin), Ampicillin (Unasyn) Use?
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UTI, gonorrhea, syphilis, meningitis, pneumonia
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Cephalexin/Cefazolin/Cefaclor/Cefuroxime/Cefixime/Ceftriaxone Class?
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Antibiotic
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Cephalexin/Cefazolin/Cefaclor/Cefuroxime/Cefixime/Ceftriaxone Group?
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Cephalosporins
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Cephalexin/Cefazolin/Cefaclor/Cefuroxime/Cefixime/Ceftriaxone Mechanism?
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Breaks down bacterial cell wall (similar to penicillins)
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Cephalexin/Cefazolin/Cefaclor/Cefuroxime/Cefixime/Ceftriaxone Effect?
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Bacteriocidal
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Cephalexin/Cefazolin/Cefaclor/Cefuroxime/Cefixime/Ceftriaxone Use?
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Not first drug of choice, similar to penicillins
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Cefepime Class?
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Antibiotic
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Cefepime Group?
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4th generation Cephalosporin
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Cefepime Mechanism?
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Breaks down bacterial cell wall (similar to penicillins)
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Cefepime Effect?
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Bacteriocidal
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Cefepime Use?
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Not first drug of choice, similar to penicillins
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Amikacin/Gentamicin/Neomycin Class?
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Antibiotic
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Amikacin/Gentamicin/Neomycin Group?
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Aminoglycosides
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Amikacin/Gentamicin/Neomycin Mechanism?
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Interferes with bacterial ribosome (30S subunit) to arrest protein
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Amikacin/Gentamicin/Neomycin Effect?
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Bacteriocidal
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Amikacin/Gentamicin/Neomycin Use?
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Broad spectrum, used before abdominal surgery, Topical infections
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Tobramycin Class?
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Antibiotic
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Tobramycin Group?
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Aminoglycosides
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Tobramycin Mechanism?
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Interferes with bacterial ribosome (30S subunit) to arrest protein
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Tobramycin Effect?
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Bacteriocidal
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Tobramycin Use?
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Minor eye infections
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Azithromycin/Clarithromycin/Erythromycin Class?
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Antibiotic
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Azithromycin/Clarithromycin/Erythromycin Group?
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Macrolides
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Azithromycin/Clarithromycin/Erythromycin Mechanism?
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Interferes with bacterial ribosome (50S subunit) to arrest protein
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Azithromycin/Clarithromycin/Erythromycin Effect?
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Bacteriostatic at low doses, Bacteriocidal at high doses
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Azithromycin/Clarithromycin/Erythromycin Use?
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Pneumonia, ulcers, syphilis, UTIs (alternative for penicillin allergy)
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Ciprofloxacin/Levofloxacin/Norfloxacin/Gatifloxicin/Moxifloxican Class?
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Antibiotic
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Ciprofloxacin/Levofloxacin/Norfloxacin/Gatifloxicin/Moxifloxican Group?
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Fluoroquinolones
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Ciprofloxacin/Levofloxacin/Norfloxacin/Gatifloxicin/Moxifloxican Mechanism?
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Inhibits bacterial DNA gyrase, and therefore DNA synthesis
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Ciprofloxacin/Levofloxacin/Norfloxacin/Gatifloxicin/Moxifloxican Effect?
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Bacteriocidal
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Ciprofloxacin/Levofloxacin/Norfloxacin/Gatifloxicin/Moxifloxican Use?
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UTI, gonorrhea, anthrax, RTI
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Tetracycline/Minocycline Class?
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Antibiotic
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Tetracycline/Minocycline Group?
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Tetracyclines
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Tetracycline/Minocycline Mechanism?
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Inhibits bacterial ribosome (30 S subunit)
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Tetracycline/Minocycline Effect?
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Bacteriostatic
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Tetracycline/Minocycline Use?
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Broad spectrum (Rocky Mountain spotted fever, typhus fever, ricketts, chlamydial infection, cholera, amebiasis, Penicillin alternative, fonorrhea, syphilis, Lyme disease, anthrax)
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Doxycycline Class?
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Antibiotic
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Doxycycline Group?
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Tetracyclines
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Doxycycline Mechanism?
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Inhibits bacterial ribosome (30 S subunit)
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Doxycycline Effect?
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Bacteriostatic
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Doxycycline Use?
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Traveler's diarrhea
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Chloramphenicol Class?
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Antibiotic
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Chloramphenicol Group?
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Micellaneous (second line)
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Chloramphenicol Mechanism?
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Inhibits bacterial ribosome (50S subunit)
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Chloramphenicol Effect?
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Bacteriostatic
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Chloramphenicol Use?
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Ricketss, Chlymidia, DOC for typhoid fever
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Clindamycin Class?
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Antibiotic
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Clindamycin Group?
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Miscellaneous
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Clindamycin Mechanism?
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Inhibits protein synthesis
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Clindamycin Efffect?
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Bacteriostatic
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Clindamycin Use?
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For bacteria that are penicillin-resistant, acne
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Spectinomycin Class?
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Antibiotic
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Spectinomycin Group?
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Miscellaneous
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Spectinomycin Mechanism?
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Inhibits bacterial ribosome
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Spectinomycin Effect?
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Bacteriostatic
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Spectinomycin Use?
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Uncomplicated gonorrhea (penicillin alternative)
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Vancomycin Class?
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Antibiotic
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Vancomycin Group?
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Miscellaneous
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Vancomycin Mechanism?
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Supresses cell wall synthesis
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Vancomycin Effect?
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Bacteriocidal
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Vancomycin Use?
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Osteomyelitis, endocarditis, staph pneumonia, pseudomembraneous colitis
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Linezolid Class?
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Antibiotic
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Linezolid Group?
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miscellaneous
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Linezolid Mechanism?
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inhibits protein synthesis
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Linezolid Effect?
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Bacteriostatic
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Linezolid Use?
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Fights staph, strep, enterococci (and drug resistant bacteria)
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Mupirocin Class?
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Antibiotic
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Mupirocin Group?
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Miscellaneous
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Mupirocin Mechanism?
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interfers with tRNA synthese (binds to isoleucyl tRNA synthetase)
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Mupirocin Effect?
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Bacteriocidal
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Mupirocin Use?
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cutaneous streptococcal and staphylococcal infection
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Isoniazid Class?
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Antimycobacterials
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Isoniazid Group?
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1st line of TB drug
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Isoniazid Mechanism?
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Interferes with the synthesis of protein, nucleic acid, and lipids
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Isoniazid Effect/
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Bacteriocidal
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Isoniazid Use?
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TB
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Ethambutol Class?
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Antimycobacterials
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Ethambutol Group?
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1st line of TB drugs
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Ethambutol Mechanism?
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Inhibits RNA synthesis
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Ethambutol Use?
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TB; Used as an alternative to isoniozid and streptomycin
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Pyrazinamide Class?
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Antimycobacterial
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Pyrazinamide Group?
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1st line of TB drugs
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Pyrazinamide Use?
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TB, used in combination with isoniazid and rifampin
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Rifampin Class?
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Antimycobacterial
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Rifampin Group?
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1st line of TB drugs
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Rifampin Mechanism?
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Inhibits DNA-dependent RNA polymerase
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Rifampin Use?
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TB; broad spectrum; anti-leprosy
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Cycloserine Class?
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Antimycobacterial
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Cycloserine Group?
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2nd line of TB drugs
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Streptomycin Class?
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Antimycobacterial
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Streptomycin Group?
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2nd line of TB drugs
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Dapsone Class?
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Antimycobacterials
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Dapsone Group?
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Anti-leprosy
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Dapsone Mechanism?
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Inhibits folate synthesis
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Dapsone effect?
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bacteriostatic
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Clofazimine Class?
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Antimycobacterials
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Clofazimine Group?
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Anto-leprosy
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Minocycline Class?
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Antimycobacterials
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Minocycline Group?
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Anti-leprosy
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Zanamivir Class?
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Antivirals
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Ritonavir Class?
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Antivirals
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Amantadine/Rimantadine Class?
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Antivirals
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Amantadine/Rimantadine Mechanism?
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inhibits viral attachment and uncoating
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Amantadine/Rimantadine Use?
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Influenza A (flu), RTI, parkinsons
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Acyclovir/Valacyclovir/Famciclovir Class?
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Antivirals
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Acyclovir/Valacyclovir/Famciclovir Mechanism?
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Inhibits viral DNA synthesis
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Acyclovir/Valacyclovir/Famciclovir Use?
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Herpes Zoster
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Ganciclovir/Foscarnet/Cidifovir Class?
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Antivirals
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Ganciclovir/Foscarnet/Cidifovir Group?
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Nucleoside analogs
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Ganciclovir/Foscarnet/Cidifovir Mechanism?
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Inhibits viral DNA polymerase
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Ganciclovir/Foscarnet/Cidifovir Use?
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CMV (cytomegalovirus), retinitis pigmentosa
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Ribavirin Class?
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Antivirals
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Ribavirin Group?
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Nucleoside
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Ribavirin Mechanism?
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viral nucleic acid synthesis
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Ribavirin Use?
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Broad- viral pneumonia
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Zidovudine Class?
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Antivirals
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Zidovudine Group?
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Nucleoside
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Zidovudine Mechanism?
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Terminates viral replication
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Zidovidine Use?
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Prevents perinatal transfer of HIV
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Didanosine Class?
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Antivirals
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Didanosine Group?
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Nucleosides
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Didanosine Mechanism?
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Inhibits HIV Replication (RTI revers transcriptase inhibitor)
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Didanosine Use?
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HIV
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