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18 Cards in this Set
- Front
- Back
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CRH
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diagnostic test… is cushings (secondary) due to ectopic or pituitary.. Pituitary will be more than more than 2x (petrosal:serum) cortisol
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thyrotropin
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TSH, diagnostic test… did post surgical resection of hyperthyroid carcinoma get all of it… this will increase amount of radioactive iodine uptake if carcinoma there
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thyrotropin releasing hormone
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TRH, diagnostic test… is hypothyroidism secondary to pituitary malfunction
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bromocriptine
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dopamine agonist at D2… for hyperprolactinemia and adjunct with octreotide for Acromegaly
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cosyntropin
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ACTH, diagnostic test… increases cholesterol esterase in adrenal glands, to see if addison's, also to differentiate between adrenal hyperplasia and ovarian hyperplasia
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GH
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somatropin, somatrem… GH deficient adults and children, peripheral edema, no in malig
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insulin like growth factor
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mecasermin… in GH deficient children only with those IGF deficiency or GH gene deletion who have antibodies, no in malig
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GHRH
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semorelin… to determine if hypothalamic dysfxn, no in malig
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GHRH receptor antagonist
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octreotide, somatostatin… acromegaly on people who can't surgery yet, gastrinoma, glucagonoma, VIPoma, insulinoma, carcinoid
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GH receptor antagonist
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pegvistomant… most effective for acromegaly
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male infertility
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hCG (LH) then FSH and hCG
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female infertility
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FSH and leuprolide / ganirelix then hCG
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clomiphene
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induce ovulation, estrogen antagonist in pituitary increases LH, FSH
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GnRH, gonadorelin
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induce ovulation, cryptorchidism, delayed puberty
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long acting GnRH
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leuprolide, goserelin… long term suppression of LH, FSH, for precocious puberty, endometriosis, polycystic ovarian syndrome, first phase in female infertility
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GnRH antagonist
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ganirelix acetate… first phase of female infertility
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AVP
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V1 receptors causes vasoconstriction, GI bleeding
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vasopressin (DDAVP)
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V2 for central diabetes insipidus
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