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50 Cards in this Set

  • Front
  • Back
This beta blocker is the longest acting
Nadolol
These beta blockers are less lipid soluble
Acebutolol and atenolol
This beta blocker is highly lipid soluble and may account for side effects such as nightmares
Propranolol
Clinical uses of these agents include treatment of HTN, angina, arrhythmias, chronic CHF, and selected post MI patients
Beta blockers
Toxicity of these agents include bradycardia, AV blockade, exacerbation of acute CHF; signs of hypoglycemia may be masked (tachycardia, tremor, and anxiety)
Beta blockers
Glaucoma (all agents topical except for diuretics)
Cholinomimetics that increase outflow, open trabecular meshwork, and cause ciliary muscle contraction (3)
Pilocarpine, carbachol, physostigmine

PCP
Nonselective alpha agonists that increases outflow, probably via the uveoscleral veins (2)
Epinephrine, dipivefrin

uveosclero - vefrine
Selective alpha agonists that decreases aqueous secretion (2)
Apraclonidine, brimonidine
These Beta blockers decrease aqueous secretion
Timolol (nonselective), betaxolol (selective)
This diuretic decreases aqueous secretion due to lack of HCO3- ion. Causes drowsiness and paresthesias, alkalinization of the urine may precipitate calcium salts, hypokalemia, acidosis
Acetazolamide
This prostaglandin causes increased aqueous outflow
Prostaglandin PGF2a
Antihypertensive Agents
Inhibit angiotensin-converting enzyme (ACE)
ACE inhibitors
Captopril and enalapril (-OPRIL ending) are
ACE inhibitors
SE of ACE inhibitors (2)
Dry cough, hyperkalemia
ACE inhibitors are contraindicated in (2)
pregnancy and with K+
Losartan and valsartan block
Angiotensin receptor
Angiotensin receptor blockers do NOT cause
Dry cough
Agents that block L-type calcium channel
Calcium channel blockers
CCB contraindicated in CHF
Verapamil
CCB with predominate effect on arteriole dilation
Nifedipine
SE of CCB (3)
Constipation, edema, and headache
Agents that reduce heart rate, contractility, and O2 demand
Beta-blockers
Subset of B-blockers that are more cardioselective
Beta-1 selective blockers
Cardioselective Beta 1-blockers
Atenolol, acebutolol, and metoprolol
Beta-blockers should be used cautiously in (3)
Asthma (bronchospastic effects),
diabetes (block signs of hypoglycemia) and
peripheral vascular disease
Non-selective Beta-blocker also used for migraine prophylaxis
Propranolol
SE of beta blockers (4)
Bradycardia, SEXUAL DYSFUNCTION,
decrease in HDL, and increase in Triglycerols (TG)
Alpha 1selective blockers (3)
Prazosin, terazosin and doxazosin (-AZOSIN ending)
Non-selective alpha1 blocker used to treat pheochromocytoma
Phenoxybenzamine
For rebound HTN from rapid clonidine withdrawal
Phentolamine
A1a-selective blocker with no effects on HTN used for BPH
Tamsulosin (Flomax)
SE of alpha blockers
Orthostatic hypotension (especially with first dose) and reflex tachycardia
Presynaptic Alpha 2 agonists used in HTN, and acts centrally (2)
Clonidine, and methyldopa
SE of methyldopa (2)
Positive Comb's test, depression
Methyldopa is contraindicated in
Geriatrics due to its CNS (depression) effects
SE of clonidine (3)
Rebound HTN, sedation, dry mouth
Direct vasodilator of arteriolar smooth muscle
Hydralazine
SE of hydralazine
Lupus-like syndrome
Arterial vasodilator that works by opening K+ channels
Minoxidil
SE of minoxidil
Hypertrichosis
IV Drug used Hypertensive Crisis
Nitroprusside
Nitroprusside vasodilates
Arteries and veins
Toxicity caused by nitroprusside and treatment
Cyanide toxicity treated with sodium thiosulfate
Diuretics
Carbonic anhydrase inhibitor
Acetazolamide
Diuretic used for mountain sickness and glaucoma
Acetazolamide
SE of acetazolamide (5)
Paresthesias, encephalopathy in patients with hepatic impairment,
acidosis, alkalinization of the urine (which may ppt. Ca salts), and
hypokalemia
MOA of loop diuretics
inhibits Na+/K+/2Cl- cotransport