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97 Cards in this Set
- Front
- Back
Organophosphate poisoning
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Atropine, pralidoxime
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Heparin overdose
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protamine
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Acetaminophen tox
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N acetylcysteine
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Drug requires dose reduction of 6MP
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Allopurinol
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ACTH analog for diagnosis
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Cosyntropin
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Side effects of spironolactone
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Gynecomastia, hyperkalemia
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SERM for prevention of osteoporosis and breast cancer reduction
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Raloxifene
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Drug used with testosterone for male fertility
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leuprolide
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1st gen that is highly sedating
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diphenhydramine
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Agents for reduction of postpartum bleeding
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oxytocin, ergonovine, ergotamine
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5hT3 antagonist used in chem. Induced emesis
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ondansetrone, ganisetron, dolasetron
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H1 blocker than is also serotonin antagonist
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cyproheptadine
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Tissue pain, edema, inactivated by ACW
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Bradykinin
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Inhibitor of lipoxygenase
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zileuton
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Used to maintain patency of ductus
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PGE1
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Muscarinic antagonist used in asthma
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ipratroprium
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MOA action of cromolyn
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mast cell stabilizer
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MOA of vanco
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blocks cell wall by sequestration
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Cheap wide spectrum antibiotic for otitis media
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amoxicillin
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DOC for influenza A
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oseltamivir
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Non benzo used for sleep
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zolpidem
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Benzo overdose (antagonist)
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flumazenil
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DOC for status epilepticus
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Diazepam
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Agent used in the treatment of alcoholism that causes flushing nausea headache
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disulfiram
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DOC for myoclonic seizures
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valproic acid
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SE of phenytoin
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gingival hyperplasia, nystagmus, ataxia
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SE for lamotrigine
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Steven Johnson
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DOC for malignant hyperthermia
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dantrolene
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Gaba agonist in the spinal cord
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baclofen
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MOA of neuroleptic
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dopamine blockade
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Antipsychotic used in the treatment of psychiatric patients with dementia
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risperidone
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Agent more frequently associated with extrapryamidal side effects
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haloperidol
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Drug used for neuroleptic malignant syndrome
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dantrolene
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Antipsychotic having the strongest autonomic effects
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thioridazine
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DOC for bipolar disorder
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lithium
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Time needed for full effect of antidepressants
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2 to 3 weeks
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TCA chronic pain, enuresis ADD
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imipramine
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Premenstral dysphoric disorder
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fluoxetine
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SSRI side effects
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CNS stimulation, GI upset
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Opioid available trans dermally
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fentanyl
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Date rape drug
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flunitrazepam
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Treatment of myasthenia gravis
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pyridostigmine
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SE ACE inhibitors
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dry cough, hyperkalemia
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CCB contraindicated in CHF
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verapamil
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Diuretic used for mountain sickness and glaucoma
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acetazolamide
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ADH agonist for diabetes insipitus
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desmopressin
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Agent to treat torsades de pointes
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magnesium sulfate
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MOA of sildenafil
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inhibits phosphodiesterase 5 enchancing effects of NO increases in cGMP
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MOA of colchincine
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inhibitor of microtubule assembly
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Allopurinol inhibits
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xanthine oxidase
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Strength of interaction between drug and its receptor
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Affinity
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Amount of drug necessary to elicit a biologic effect; refers to the drug's strength
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Potency
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Antidote used for cyanide poisoning
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Nitrites
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Antidote used for iron salt toxicity
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Deferoxamine
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MOA of cisplatin
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Alkylating agent
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Anticancer drug also used in RA, produces acrolein in urine that leads to hemorrhagic cystitis
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Cyclophosphamide
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Used for hairy cell leukemia; it stimulates NK cells
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Interferon alpha
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Vitamins containing iron should NOT be taken simultaneously with levothyroxine because:
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Iron deiodinates thyroxine
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Long acting glucocorticoids
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Betamethasone and dexamethasone
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Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis
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Aminoglutethimide
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Antiprogestin used as potent antagonist of GC receptor
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Mifepristone
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Antifungal agent used for inhibition of all gonadal and adrenal steroids
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Ketoconazole
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Anti-androgen used for hirsutism in females
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Cyproterone acetate
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Long acting insulin *
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Ultralente (humulin U)
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Examples of alpha-glucosidase inhibitors (AGI)
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Acarbose, miglitol
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Amino acid derivative, active as an insulin secretagogue *
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Nateglinide
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MOA of thiazolindinediones
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Stimulate PPAR-gamma receptor to regulate CHO and lipid metabolism
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Names of three bisphosphonates available IV
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Pamidronate, zoledronate, ibandronate
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1st generation antihistamine that is highly sedating **
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Diphenhydramine
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H1 blocker that is also a serotonin antagonist
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Cyproheptadine
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Drug causing depletion of substance P (vasodilator) *
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Capsaicin
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Inhibitor of lipoxygenase *
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Zileuton
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Long acting beta 2 agonist used in asthma
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Salmeterol
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Muscarinic antagonist used in asthma *
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Ipratropium
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MOA of corticosteroids
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inhibit phospholipase A2
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Type of resistance found with vancomycin
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Point mutation
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Meningitis prophylaxis in exposed patients *
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Rifampin
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PCN active against pseudomonas
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Carbenicillin, piperacillin and ticarcillin
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MOA of sulfonamides*
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Inhibit dihydropteroate synthase
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Treatment of resistant pseudomembranous colitis
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ORAL vancomycin
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Common side effect of Rifampin *
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Red urine discoloration
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DOC for influenza A *
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Oseltamivir
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Antivirals that are teratogens
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Delavirdine, efavirenz, and ribavirin
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HIV med used to reduce transmission during birth
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Nevirapine
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MOA of erythromycin
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Inhibition of protein synthesis at the 50s subunit of ribosome
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Benzodiazepine used for anxiety
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Alprazolam
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Neurologic SE of benzodiazepines
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Anterograde amnesia
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Benzodiazepine that is used for anesthesia
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Midazolam
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Agents that inhibit acetaldehyde dehydrogenase
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Disulfiram, metronidazole, certain sulfonylureas and cephalosporins
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MOA for Ethosuximide
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Calcium channels
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Drug of choice for myoclonic seizures *
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Valproic acid
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SE for Felbamate
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Aplastic anemia and acute hepatic failure
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DOC for malignant hyperthermia that may be caused by use of halogenated anesthetics *
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Dantrolene
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Antipsychotic having the strongest autonomic effects *
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Thioridazine
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Sedation is a common side effect of these drugs, they lower seizure threshold, uses include BAD, acute panic attacks, phobias, enuresis, and chronic pain and their overdose can be deadly
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Tricyclic antidepressants (TCA)
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DOC for paroxysmal supraventricular tachycardia (PSVT)
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Adenosine
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Antidote to reverse actions of heparin *
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Protamine sulfate
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