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97 Cards in this Set

  • Front
  • Back
Organophosphate poisoning
Atropine, pralidoxime
Heparin overdose
protamine
Acetaminophen tox
N acetylcysteine
Drug requires dose reduction of 6MP
Allopurinol
ACTH analog for diagnosis
Cosyntropin
Side effects of spironolactone
Gynecomastia, hyperkalemia
SERM for prevention of osteoporosis and breast cancer reduction
Raloxifene
Drug used with testosterone for male fertility
leuprolide
1st gen that is highly sedating
diphenhydramine
Agents for reduction of postpartum bleeding
oxytocin, ergonovine, ergotamine
5hT3 antagonist used in chem. Induced emesis
ondansetrone, ganisetron, dolasetron
H1 blocker than is also serotonin antagonist
cyproheptadine
Tissue pain, edema, inactivated by ACW
Bradykinin
Inhibitor of lipoxygenase
zileuton
Used to maintain patency of ductus
PGE1
Muscarinic antagonist used in asthma
ipratroprium
MOA action of cromolyn
mast cell stabilizer
MOA of vanco
blocks cell wall by sequestration
Cheap wide spectrum antibiotic for otitis media
amoxicillin
DOC for influenza A
oseltamivir
Non benzo used for sleep
zolpidem
Benzo overdose (antagonist)
flumazenil
DOC for status epilepticus
Diazepam
Agent used in the treatment of alcoholism that causes flushing nausea headache
disulfiram
DOC for myoclonic seizures
valproic acid
SE of phenytoin
gingival hyperplasia, nystagmus, ataxia
SE for lamotrigine
Steven Johnson
DOC for malignant hyperthermia
dantrolene
Gaba agonist in the spinal cord
baclofen
MOA of neuroleptic
dopamine blockade
Antipsychotic used in the treatment of psychiatric patients with dementia
risperidone
Agent more frequently associated with extrapryamidal side effects
haloperidol
Drug used for neuroleptic malignant syndrome
dantrolene
Antipsychotic having the strongest autonomic effects
thioridazine
DOC for bipolar disorder
lithium
Time needed for full effect of antidepressants
2 to 3 weeks
TCA chronic pain, enuresis ADD
imipramine
Premenstral dysphoric disorder
fluoxetine
SSRI side effects
CNS stimulation, GI upset
Opioid available trans dermally
fentanyl
Date rape drug
flunitrazepam
Treatment of myasthenia gravis
pyridostigmine
SE ACE inhibitors
dry cough, hyperkalemia
CCB contraindicated in CHF
verapamil
Diuretic used for mountain sickness and glaucoma
acetazolamide
ADH agonist for diabetes insipitus
desmopressin
Agent to treat torsades de pointes
magnesium sulfate
MOA of sildenafil
inhibits phosphodiesterase 5 enchancing effects of NO increases in cGMP
MOA of colchincine
inhibitor of microtubule assembly
Allopurinol inhibits
xanthine oxidase
Strength of interaction between drug and its receptor
Affinity
Amount of drug necessary to elicit a biologic effect; refers to the drug's strength
Potency
Antidote used for cyanide poisoning
Nitrites
Antidote used for iron salt toxicity
Deferoxamine
MOA of cisplatin
Alkylating agent
Anticancer drug also used in RA, produces acrolein in urine that leads to hemorrhagic cystitis
Cyclophosphamide
Used for hairy cell leukemia; it stimulates NK cells
Interferon alpha
Vitamins containing iron should NOT be taken simultaneously with levothyroxine because:
Iron deiodinates thyroxine
Long acting glucocorticoids
Betamethasone and dexamethasone
Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis
Aminoglutethimide
Antiprogestin used as potent antagonist of GC receptor
Mifepristone
Antifungal agent used for inhibition of all gonadal and adrenal steroids
Ketoconazole
Anti-androgen used for hirsutism in females
Cyproterone acetate
Long acting insulin *
Ultralente (humulin U)
Examples of alpha-glucosidase inhibitors (AGI)
Acarbose, miglitol
Amino acid derivative, active as an insulin secretagogue *
Nateglinide
MOA of thiazolindinediones
Stimulate PPAR-gamma receptor to regulate CHO and lipid metabolism
Names of three bisphosphonates available IV
Pamidronate, zoledronate, ibandronate
1st generation antihistamine that is highly sedating **
Diphenhydramine
H1 blocker that is also a serotonin antagonist
Cyproheptadine
Drug causing depletion of substance P (vasodilator) *
Capsaicin
Inhibitor of lipoxygenase *
Zileuton
Long acting beta 2 agonist used in asthma
Salmeterol
Muscarinic antagonist used in asthma *
Ipratropium
MOA of corticosteroids
inhibit phospholipase A2
Type of resistance found with vancomycin
Point mutation
Meningitis prophylaxis in exposed patients *
Rifampin
PCN active against pseudomonas
Carbenicillin, piperacillin and ticarcillin
MOA of sulfonamides*
Inhibit dihydropteroate synthase
Treatment of resistant pseudomembranous colitis
ORAL vancomycin
Common side effect of Rifampin *
Red urine discoloration
DOC for influenza A *
Oseltamivir
Antivirals that are teratogens
Delavirdine, efavirenz, and ribavirin
HIV med used to reduce transmission during birth
Nevirapine
MOA of erythromycin
Inhibition of protein synthesis at the 50s subunit of ribosome
Benzodiazepine used for anxiety
Alprazolam
Neurologic SE of benzodiazepines
Anterograde amnesia
Benzodiazepine that is used for anesthesia
Midazolam
Agents that inhibit acetaldehyde dehydrogenase
Disulfiram, metronidazole, certain sulfonylureas and cephalosporins
MOA for Ethosuximide
Calcium channels
Drug of choice for myoclonic seizures *
Valproic acid
SE for Felbamate
Aplastic anemia and acute hepatic failure
DOC for malignant hyperthermia that may be caused by use of halogenated anesthetics *
Dantrolene
Antipsychotic having the strongest autonomic effects *
Thioridazine
Sedation is a common side effect of these drugs, they lower seizure threshold, uses include BAD, acute panic attacks, phobias, enuresis, and chronic pain and their overdose can be deadly
Tricyclic antidepressants (TCA)
DOC for paroxysmal supraventricular tachycardia (PSVT)
Adenosine
Antidote to reverse actions of heparin *
Protamine sulfate