Pharm One Liners From Tests

Front 1

Strength of interaction between drug and its receptor

Back 1

Affinity

Front 2

Amount of drug necessary to elicit a biologic effect

Back 2

Potency

Front 3

Antidote used for cyanide poisoning

Back 3

Nitrites

Front 4

Antidote used for iron salt toxicity

Back 4

Deferoxamine

Front 5

Antidote for methotrexate toxicity

Back 5

Leucovorin

Front 6

MOA of cisplatin

Back 6

Alkylating agent

Front 7

Anticancer drug also used in RA, produces acrolein in urine that leads to hemorrhagic cystitis

Back 7

Cyclophosphamide

Front 8

Used for hairy cell leukemia; it stimulates NK cells

Back 8

Interferon alpha

Front 9

Produces disulfiram-like reaction with ethanol

Back 9

Procarbazine

Front 10

Vitamins containing iron should NOT be taken simultaneously with levothyroxine because

Back 10

Iron deiodinates thyroxine

Front 11

Long acting GC's

Back 11

Betamethasone, dexamethasone, and paramethasone

Front 12

Inhibits conversion of cholesterol to pregnenolone therefore inhibiting corticosteroid synthesis

Back 12

Aminoglutethimide

Front 13

Antifungal agent used for inhibition of all gonadal and adrenal steroids

Back 13

Ketoconazole

Front 14

Antiprogestin used as potent antagonist of GC receptor

Back 14

Mifepristone

Front 15

Anti-androgen used for hirsutism in females

Back 15

Cyproterone acetate

Front 16

Long acting insulin

Back 16

Ultralente (humulin U)

Front 17

Examples of alpha-glucosidase inhibitors (AGI)

Back 17

Acarbose, miglitol

Front 18

Amino acid derivative, active as an insulin secretagogue

Back 18

Nateglinide

Front 19

Most important potential SE of metformin

Back 19

Lactic acidosis

Front 20

MOA of thiazolindinediones

Back 20

Stimulate PPAR-gamma receptor to regulate CHO and lipid metabolism

Front 21

Only bisphosphonates available IV

Back 21

Etidronate

Front 22

1st generation antihistamine that is highly sedating

Back 22

Diphenhydramine

Front 23

H1 blocker that is also a serotonin antagonist

Back 23

Cyproheptadine

Front 24

Drug causing depletion of substance P (vasodilator)

Back 24

Capsaicin

Front 25

Inhibitor of lipoxygenase

Back 25

Zileuton

Front 26

Long acting beta 2 agonist used in asthma

Back 26

Salmeterol

Front 27

Muscarinic antagonist used in asthma

Back 27

Ipratropium

Front 28

MOA of corticosteroids"

Back 28

inhibit phospholipase A2

Front 29

Type of resistance found with vancomycin

Back 29

Point mutation

Front 30

Meningitis prophylaxis in exposed patients

Back 30

Rifampin

Front 31

MOA of sulfonamides

Back 31

Inhibit dihydropteroate synthase

Front 32

PCN active against pseudomonas

Back 32

Carbenicillin, piperacillin and ticarcillin

Front 33

Treatment of resistant pseudomembranous colitis

Back 33

ORAL vancomycin

Front 34

Common side effect of Rifampin

Back 34

Red urine discoloration

Front 35

Antivirals that are teratogens

Back 35

Delavirdine, efavirenz, and ribavirin

Front 36

HIV med used to reduce transmission during birth

Back 36

AZT (zidovudine)

Front 37

Drug used for N. gonorrhea in females

Back 37

Ceftriaxone

Front 38

MOA of erythromycin

Back 38

Inhibition of protein synthesis at the 50s subunit of ribosome

Front 39

Benzodiazepine used for anxiety

Back 39

Alprazolam

Front 40

Neurologic SE of benzodiazepines

Back 40

Anterograde amnesia

Front 41

Benzodiazepine that is used for anesthesia

Back 41

Midazolam

Front 42

Agent with zero-order kinetics

Back 42

Ethanol

Front 43

MOA for Ethosuximide

Back 43

Calcium channels

Front 44

Drug of choice for myoclonic seizures

Back 44

Valproic acid

Front 45

SE for Felbamate

Back 45

Aplastic anemia and acute hepatic failure

Front 46

Benzodiazepine used adjunctively in anesthesia

Back 46

Midazolam

Front 47

Drug used in neuroleptic malignant syndrome

Back 47

Dantrolene

Front 48

Antipsychotic having the strongest autonomic effects

Back 48

Thioridazine

Front 49

Antidepressant associated with seizures and cardiotoxicity

Back 49

Maprotiline

Front 50

Bronchodilation in asthma and COPD

Back 50

Ipratropium

Front 51

Antidote for lead poisoning

Back 51

EDTA (or EDTA and dimercarprol)

Front 52

Antidote for organophosphate/anticholinesterase poisoning

Back 52

atropine, pralidoxime (2-PAM)

Front 53

Antidote for opioid toxicity

Back 53

naloxone iv, naltrexone po

Front 54

MOA of cisplatin

Back 54

alkylating agent

Front 55

Regimen used for non-hodgkins lymphoma

Back 55

CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) plus rituximab)

Front 56

Microtubule inhibitor that causes peripheral neuropathy, foot drop (eg. ataxia), and "pins and needles" sensation

Back 56

vincristine

Front 57

acth analog used for dx of pt’s with corticosteroid abnormality

Back 57

cosyntropin

Front 58

Synthetic analog of ADH hormone used for diabetes insipidus and nocturnal enuresis

Back 58

desmopressin

Front 59

Common SE of spironolactone

Back 59

hyperkalemia, gynecomastia

Front 60

Prototype of H1 and H2 receptors

Back 60

diphenhydramine and cimetidine

Front 61

Agents used in carcinoid tumor

Back 61

Ketanserin cyproheptadine, and phenoxybenzamine

Front 62

DOC to treat chemo-induced nausea and vomiting

Back 62

odansetron

Front 63

Ergot alkaloid used as an illicit drug

Back 63

LSD

Front 64

Prostaglandin used in tx of impotence

Back 64

alprostadil

Front 65

Methylxanthine derivative used as a remedy for intermittent claudication

Back 65

Pentoxifylline

Front 66

Meningitis prophylaxis in exposed pts

Back 66

rifampin

Front 67

Technique used to diagnose perianal itching, and the drug used to treat it

Back 67

scotch tape technique, mebendazole

Front 68

MOA sulfonamides

Back 68

inhibit dihydropteroate synthase

Front 69

Anemia caused by trimethoprim

Back 69

megalobolastic anemia

Front 70

Drug used in chagas disease

Back 70

nifurtimox

Front 71

Drugs of chose for leprosy

Back 71

Dapsone, rifampin and clofazimine combination

Front 72

Antibiotic frequently used for chronic UTI prophylaxis

Back 72

sulfamethoxazole/trimethoprim

Front 73

Activation of these receptors close Ca2+ ion channels to inhibit neurotransmitter release

Back 73

Presynaptic mu, delta, and kappa receptors

Front 74

this agent used to treat dry mouth in Sjogren’s syndrome

Back 74

cevimeline

Front 75

Organophosphate anthelmintic agent with long DOA

Back 75

metrifonate

Front 76

Most toxic organophosphate

Back 76

parathione

Front 77

Tx of motion sickness

Back 77

Meclizine, Scopolamine (M,S=motion sickness)

Front 78

Losartan and valsartan block

Back 78

angiotensin receptors

Front 79

Methyldopa is contraindicated in

Back 79

geriatrics due to CNS depression

Front 80

MOA thiazide diuretics

Back 80

inhibit Na/Cl cotransport

Front 81

SE procainamide

Back 81

lupus like syndrome

Front 82

DOC for management of acute ventricular arrhythmias

Back 82

amiodarone

Front 83

DOC for paroxysmal supraventricular tachycardia; has high efficacy and short

Back 83

adenosine

Front 84

SE of sotalol

Back 84

QT and PR prolongation

Front 85

Topical DOC in impetigo

Back 85

Topical mupirocin (Bactroban)

Front 86

MOA of class III antiarrhythmics

Back 86

K channel blockade

Front 87

MOA of class IV antiarrhythmics

Back 87

Ca channel blockers

Front 88

Specific pharmacokinetic characteristic of amiodarone

Back 88

Prolonged half-life, up to six weeks

Front 89

Rapid acting insulins that do not self aggregate-

Back 89

Lispro insulin, Aspart insulin, Glulisine insulin (fast, insulins L A G)