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24 Cards in this Set
- Front
- Back
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most frequent route of metabolism
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hepatic enzymes
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MOA of phenytoin, carbamazepine, lamotrigine
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sodium channel blockade
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MOA for benzos and barbs
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GABA related targets
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MOA for ethosuximide
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calcium channels
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MOA for valproic acid at high doses
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affect calcium, sodium, and potassium channels
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DOC for tonic-clonic and partial seizures
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phenytoin and valproic acid
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DOC for febrile seizures
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phenobarbital
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DOC for absence seizures
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ethosuximide and valproic acid
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DOC for myoclonic seizures
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valproic acid
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DOC for status epilepticus
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IV diazepam for short term and phenytoin for long term
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drugs that can be used for infantile seizures
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corticosteroids
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antiseizure meds also used for bipolar affective disorder (BAD)
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valproic acid, carbamazepine, phenytoin, and gabapentin
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antiseizure drug also used for trigeminal neuralgia
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carbamazepine
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antiseizure drugs also used for neuropathic pain
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gabapentin
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anti seizure drug that exhibits nonliner metabolism, highly protein bound, causes fetal hydantoin syndrome, stimulates hepatic metabolism
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phenytoin
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SE of phenytoin
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gingival hyperplasia, nystagmus, diplopia, ataxia
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anti-seizure agent that induces formation of liver drug-metabolism enzymes, is teratogen and can cause craniofacial anomalies and spina bifida
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carbamazepine
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agent that inhibits hepatic metabolism, is hepatotoxic, and teratogen that can cause neural tube defects, and GI distress
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valproic acid
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lab values that must be monitored on valproic acid
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serum ammonia and LFTs
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SE for lamotrigine
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steven johnsons syndrome
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SE for felbamate
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aplastic anemia and acute hepatic failure
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anti-seizure medication that is also used in the prevention of migraines
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valproic acid
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carbamazepine may cause
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agranulocytosis
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anti seizure drugs used as an alternative to mood stabilization drugs
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carbamazepine, gabapentin, lamotrigine, valproic acid
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