Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
4 Cards in this Set
- Front
- Back
- 3rd side (hint)
|
Sulfonamides
|
Sulfisoxasole-UTI
sulfamethoxasole-with trimethoprim sulfadoxine-malaria with pyrimethamine azulfadine-ulcerative colitis |
MOA-inhibits folic acid synthesis.
Is broad spectrum but many ecoli and n. meningitis resistant is mostly bacteriostatic but in the absence of thymine is cidal. well absorbed in GI, good distribution even in CSF, metabolized in liver excreted renally toxicity-crystalluria, sulfa stones, acute hemolytic anemia-G6PD, kernicterus, rash, nausea, vomiting, hepatic necrosis interactions-displaces warfarin, methotrexate, chlorpropamide, tolbutamide, decrease activity of procaine used for UIT, nocardia, PRP, toxo, malaria, listeria, aerobic bacteria |
|
|
Dihydrofolate reductase inhibitors
|
Pyrimethamine
Trimethoprim |
act synergistically with sulfa
|
|
|
quinolones
|
nalidixic acid
ciprofloxacin |
nalidixic acid-UTI
ciprofloxacin-fluoroquinolone, broad spectrum, poor for anaerobes, ok for strep |
|
|
Nitrofurantoin
|
rarely used urinary antiseptic
PULMONARY FIBROSIS AND INFLAMMATION |
|
