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17 Cards in this Set
- Front
- Back
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Where does Tb attack?
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Highly vascular organs
Lung (Primary site) Brain, bone, kidney, liver |
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Mycobacterium infections,
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Aerobic bacillus
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How is Mycobacterium infection passed?
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-HUmans
-Caows, birds not common -droplet precausions |
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First-line drugs for TB are?
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isoniazid (INH)
-drug of choice -metab in liver"slow acetylators" -used to prevent and to tx TB |
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Second-line drugs for Tb?
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-Capreomycin
-cycloserine |
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Drug considerations for antitubercular's
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-test 1st mycob. sp. to prevent MDR-TB
-start drug regime prior to knowing the test results. |
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What is the problem with successful therapy?
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-patient nonadherence
-increased drug resistance. -Drug toxicity |
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How do antitubercular's work?
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-protein wall synthesis inhibitors
-cell wall synt inhibs. |
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What is MDR-TB?
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Multidrug-resistant TB
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Adverse effects of Antituberculars?
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-INH (hepatotox, periph. neuritis)
-Ethambutol( retrobulbar neuritis, blindness -Rifampin |
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Nursing Implicacations of Anti TB drugs include?
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-liver function tests
-Med Hx and ass. |
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Patient teaching is?
Anti TB drugs |
Critical
-tx up to 24 months -meds sametime every day -strict adherance is needed for cure |
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When is the patient contagious?
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-intially, proper hygeneto prevent spread of infection
-Nutrition and rest |
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Can a patient use Alcohol, OTC, or oral contraceptives with Antitubercular's?
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NO, check with Dr. on other meds. and use other birth control.
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What color will rifampin turn your urine, stool, saliva, etc.?
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Orange
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While on INH, what drug canbe used to combat neurologic adverse effects?
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Pyridoxine
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What adverse effects should be reported to a physician?
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fatigue, nausea, vomiting, numbness, fever, loss of apppetite, depression, jaundice
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