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20 Cards in this Set

  • Front
  • Back
Tubocuraine
MM Relaxant-non depolarizing blocker

1. Can cause histamine release -REFLEX TACHYCARDIA
2. Blocks autonomic ganglia (at high conc)
3. Long acting (60-120 min) w/slow onset
MM relaxant

Unique SE:
Hypotension & Reflex Tachycardia
Tubocuraine (due to Histamine release)
Atracurium
MM relaxant - nondepolarizing blocker

1. Intermediate acting (20-45 min)
2. Slight histamine release (less CV effects)

preferred during renal failure
Cisatracurium
MM relaxant - nondepolarizing blocker

1. Intermediate acting (20-45 min)

**most spontaneous elimination
MM relaxant

unique feature:
Mostly spontaneous elimination
Cisatracurium
non-depolarizing blocker
intermediate acting
Mivacurium
MM relaxant - non-depolarizing blocker

1. Can cause histamine release
2. Short-acting (10-20min)

special use: endotracheal intubation
- Rapidly hydrolyzed by plasma esterases - thus preferred during renal failure
MM relaxant:

specific use- Endotrachael Intubation
Mivacurium
-short acting (10-20min)

Rocuronium
1. Intermediate acting (20-45 min) - w/fastest onset of all*

Succinylcholine
-DOA 5-10min
Pancuronium
MM relaxant - non-depolarizing blocker

1. Vagoylytic; moderate blockage of cardiac muscarinic R
--> inc HR and BP

2. Long acting (60-120 min)
MM relaxant

SE: blocks muscarinic R
vagolytic
Pancuronium

1. Moderate blockage of cardiac muscarinic R
2. Long acting (60-120 min)
Rocuronium
MM relaxant; non-depolarizing blocker

1. Intermediate acting (20-45 min) - w/fastest onset of all*

use: endotracheal intubation
MM relaxant

unique: fastest onset
Rocuronium

1. Intermediate acting (20-45 min)
Succinylcholine
MM relaxant; depolarizing blocker

-flaccid paralysis
uses: anesthesia adjunct, endo intubation, prevent convulsions in ECT
-short DOA 5-10min

SE:-hyperkalemia (due to hyperpolarization), inc IOP, apnea, Malignant Hyperthermia
MM relaxants;

SE: Hyperkalema, Malignant Hyperthermia, Increased IOP
Succinylcholine
Diazepam
(Valium)
spasmolytic MM relaxant

-enhances GABA's presynaptic inhib on GABA-A

use: spastic states, sedation
MM relaxants

use: spastic states
Diazepam
Baclofen
Tizanidine
Gabapentin
Baclofen
spasmolytic MM relaxant

GABA-B agonist--> presyn inhib (dec release of excitatory NT) & hyperpolarization

uses: spastic states; trigeminal neuralgia
misc: intrathecal administration
SE: lassitude (fatigue)
MM relaxant

special use: Trigeminal Neuralgia
Baclofen
MM relaxant

unique SE: Lassitude
Baclofen
Tizanidine
spasmolytic MM relaxant

alpha2 agonist--> inc pre/postsynap inhib
uses: spasticity for MS/SCI

SE: asthenia (weakness/loss of strength), sedation
MM relaxant

unique SE: Asthenia & Sedation
Tizanidine