Pharm Mini 1

Front 1

carbachol

Back 1

activation of M receptors. contraction of ciliary muscle. increase flow through canal of Schelmm

Front 2

pilocarpine

Back 2

activation of M receptors. contraction of ciliary muscle. increase flow through canal of Schelmm

Front 3

ecothiopate

Back 3

acetylcholine esterase inhibitor. increase the outflow in treatment of glacouma.

Front 4

betaxolol

Back 4

beta blocker. block NE at ciliary epithelium. decrease aqueous humor formation

Front 5

timolol

Back 5

beta blocker. block NE at ciliary epithelium. decrease aqueous humor formation

Front 6

apraclonidine

Back 6

a2 agonist. decrease NE release prejunctional..decrease aqueous humor

Front 7

epinephrin

Back 7

increase outflow in glacouma

Front 8

acetazolamide

Back 8

carbonic anhydrase inhibitor. decrease HCO3 and decreaase aqueous humor formation

Front 9

dorzolamide

Back 9

carbonic anhydrase inhibitor. decrease HCO3 and decrease aqueous humor formation

Front 10

latanoprost

Back 10

prostaglandin PGF2 alpha analog. increase the outflow through the meshwork

Front 11

bethanecol

Back 11

muscarinic agonist used in the treatment of parlytic ileus and urinary retention

Front 12

methacholine

Back 12

muscarinic agonist. diagnostic of bronchial hyperactivity

Front 13

pilocarpine

Back 13

treatment in glaucoma and xerostomia. sjogren syndrome

Front 14

edrophonium

Back 14

acetylcholinesterase inhibitor. diagnostic of myastenia gravis

Front 15

physostigmine

Back 15

acetylcholinesterase inhibitor. tertiary amines (enter CNS). treatment of glaucoma, antidote in overdose of atropine

Front 16

neostigmine
pyridostimine

Back 16

anticholinesterase inhibitor. quarternary amine (no CNS). treatment of myastenia gravis, ileus, and urinary retention. reversal of nondepolarizing NM blocker

Front 17

donepsezil, tacrine

Back 17

acetylcholinesterase inhibitor. treatment in alzheimer's disease

Front 18

atropine

Back 18

anticholinergic. antispasmodic, antidiarrheal, treatment of cholinergic toxicity. blocks bradycardia during anesthesia

Front 19

tropicamide

Back 19

anticholinergic. mydriasis and cycloplegia: recovery in 2 hours.

Front 20

ipratropium

Back 20

treatment of asthma and COPD. no change in mucus

Front 21

scopolamine

Back 21

treatment in motion sickness. blocks transmittion of VIII in the vestibular cocular system

Front 22

glycopyrrolate

Back 22

treatment of peptic ulcers, antispasmodic

Front 23

benzatropine, trihexphenidyl

Back 23

treatment of parkinson disease. correcting acetylcholine and dopamine balance in the stiatonigral tract and nigrostriatal tract

Front 24

d-tubocurarine, pancuronium, atracurium

Back 24

competitive blocking of acetylcholine at neuromuscular receptor Nm. antidote is neostigmine

Front 25

mivacurium

Back 25

competitive blocking of acetylcholine at Nm. very short duration of action. metabolized by plasma pseudocholine esterase.

Front 26

benzodiazepines

Back 26

potentiates GABA actions at GABAa receptors. They reduce the tone of spinal motorneurons

Front 27

Baclofen

Back 27

direct agonist at GABAb receptors in the spinal cord. as good as diazepam with less sedation

Front 28

Dantrolene

Back 28

acts directly on the skeletal muscle to decrease contractility. block Ca release from the sarcoplasmic reticulum. treatment in malignant hyperthermia

Front 29

phenelzine, tranylcypromine

Back 29

MAO type A inhibitor. treatment of depression

Front 30

selegiline

Back 30

MAO type B inhibitor. treatment of parkinson's disease.

Front 31

methyl-p-tyrosine

Back 31

interfers with NE synthesis

Front 32

amphetamine, ephedrine

Back 32

displacement of mobile pool (indirect acting sympathomimetic)

Front 33

cocaine, TCA

Back 33

blockade of reuptake of NE (indirect acting sympathomimetic)

Front 34

reserpine

Back 34

blockade of granular uptake of NE. used in hypertension

Front 35

guanethedine

Back 35

blockade of release of NE from granules. used in hypertension

Front 36

clonidine, theyldopa

Back 36

presynaptic a2 agonist

Front 37

phenylephrine

Back 37

a1 agonist. vasoconstriction. decongestant, mydiasis without cycloplegia, reflex bradycardia

Front 38

methoxamine

Back 38

used for paroxymal atrial tachycardia. vasoconstriction blood vessels and increase BP giving a reflex bradycardia.

Front 39

clonidine

Back 39

central a2 agonist effect that decrease BP

Front 40

alpha-methyl dopa

Back 40

a2 agonist. a prodrug

Front 41

dobutamine

Back 41

B agonist. B1>B2. treatment of acute CHF

Front 42

isoproterenol

Back 42

B1=B2. treatment of bronchospasm. side effects is flushing and arrythmias.

Front 43

albuterol

Back 43

selective B2 agonist. treatment of acute asthma

Front 44

metaproterenol

Back 44

selective B2 agonist. bronchodilator

Front 45

salmetrol

Back 45

selective B2 agonist. long acting bronchodilator

Front 46

terbutaline

Back 46

selective B2 agonist bronchodilator and tocolytics

Front 47

ritodrine

Back 47

selective B2 agonisttocolytics. prevent premature labor

Front 48

phentolamine

Back 48

a1, a2 blocker. competitive.
a1 blockade leads to decrease TPR and decrease BP. reflex tachycardia.

Front 49

phenoxybenzamine

Back 49

a1, a2 non competitive blockers. short term use in pheochromocytoma. reflex tachycardia, miosis, inhibition of ejaculation.

Front 50

prazocin, doxazocin, terazocin

Back 50

selective a1 blocker. treatment of hypertension and BPH (relaxes spincter). less reflex tachycardia because of NE feedback by alpha 2 is in tact

Front 51

tamsulosin

Back 51

selective a1 blocker only for BPH. it will not lower blood pressure

Front 52

yohimbine

Back 52

alpha 2 blocker. treatment of postural hypotension and impotence. hypotension that comes on when the person stands up.

Front 53

mirtazapine

Back 53

a2 blocker. treatment of depression. cause weight gain. fight both depression and anoerxia.