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10 Cards in this Set
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- Back
- 3rd side (hint)
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Anticoagulant
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Heparin
Unfractionated Heparin Low molecular weight Heparin Fondaparinux Warfarin |
Used to recover flow
Heparin is used as IV bolus, potentiates antithrombin III, reversed by protamine (acidic, neutralizes heparin) Unfractionated is the least specific. LMWH and Fondaparinus are more specific, for LMWH anti Xa levels are checked. Warfarin is NOT acute, has half life of 3-5 days and should not be given as loading dose. Reversed by giving vit K. |
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Thrombolytics
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Streptokinase
Alteplase Reteplase Tenectaplase |
Streptokinas and alteplase are prototypic, all turn plasminogen to plasmin and have a short half life. Absolute contraindication in surgery within 10 days, serious GI bleed in last 3 months, active bleeding, CVA in past 3 months, aortic dissection, acute pericarditis. Relative contraindication with acute HTN, and age over 75.
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ADP antagonists
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Ticlopidine, clopidogrel, prasugrel
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block ADP, by suppressing platelet activation, used to prevent a second MI, benefit to TIA and stroke patients. Used in Angioplasty and coronary stent procedures.
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GPIIb/IIIa blocker
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abciximab
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blocks sruface receptor for cell-cell interaction in platelets. Used mostly in cath labs.
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Control of Arrhythmias, Ventricular
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Lidocaine and amiodarone are drugs of choice. More so lidocaine
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Control of Bradycardia
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Muscarinic blocker-atropine IV
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Pulmonary Congestion
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Furosemide-reduce volume
Morphine-pain and helps with congestion Aminophylline-PDEi |
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Low CO/BP, high ventricular pressure-SHOCK
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Nitroprusside-vasodilation
DOPamine (B1 inotropic), DOBUTamine (B 1 inotropic some B2), Milrinone (PDEIII inhibitor) for increased CO. |
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RV failure, low CO and BP
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add volume
increase LV force. DOPamine (B1 inotropic), DOBUTamine (B 1 inotropic some B2), Milrinone (PDEIII inhibitor) for increased CO. |
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Prevent 2nd MI
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BB (propranolol, metoprolol-used more, esmolol-acute IV)
aspirin CCB ADP antagonist Angiotensin inhibitor (angiotensin II causes cardiac hypertrophy) |
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