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37 Cards in this Set
- Front
- Back
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what are the majority of CAP's caused by?
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strep
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what is the causative agent in the majority of cellulitis?
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staph
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DOC for febrile neutropenia?
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4th gen : CEFEPIME
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doc to treat staph infection?
(usually cellulitis) |
ANCEF (cefazolin) 1st gen
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doc for pseudomonas?
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big gun= zosyn IV (piperacillin beta lactamase inhibitor combo)
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doc for legionaire's?
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erythromycin
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doc for CAP?
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macrolide; erythromycin
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which drugs' MOA inhibits the bacterial synthesis of folic acid?
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sulfanamides
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which big gun causes "red man syndrome"
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vanco
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DOC for legionella?
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zithromax/Azithromicin: macrolide
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what is an alternative drug for HIV p to use if they have an allergy to bactrim?
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Dapsone
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what are some AE to sufanamides?
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SJS
hemolytic anemia hypoglycemia jaundice kernicterus (neonates) agranulocytosis |
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due to the metabolism of the sulfanamides which particular population are they good for?
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metabolized by acetylation: good for the elderly
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what is the DOC for pregnant fe with UTI?
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macrodantin
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what drug is used for the prophylaxsis of PCP in hiv patients?
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TMP
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what are some uses for TMP?
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it is a sulfanamide:
UTI salmonella burns PCP prophylaxsis |
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what is the MOA of penicillins?
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inhibit the synthesis of the cell wall
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what can you use for pregnant female with cellulitis?
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keflex/Cephalexin 1st gen
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what class of abx is considered the anti-staphylococcal penicillins?
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the CONDM drugs:
cloxacillin oxacillin nafcillin dicloxacillin methicillin |
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what are the anti-pseudomonal penicillins?
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ticarcillin
piperacillin carbecillin |
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doc for pseudomas?
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piperacillin + aminoglycoside for double coverage
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what bugs are the 1st gen ceph's good for?
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PEK
Preoteus mirabilis E.coli Klebsiella |
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two examples of 1st gen?
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cephalexin/keflex
cefadroxil/Duracef |
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what bugs are the 2nd gen ceph's good for?
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HEN PEK
PEK + H.flu enterobacter Neisseria |
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name 3 2nd gen ceph's that cover anerobes?
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metal tan fox!
cefmetazole cefotetan cefoxitin |
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what are 3 common diseases Rocephin is used to treat?
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lyme disease
gonorrhea CAP meningitis |
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what bugs are 3rd gen ceph's good to treat?
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PEEK, some HEN
Proteus E.coli enterobacter klebsiella |
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common ceph to cross the BBB?
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cefipime
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what are the 3 ONLY effective agents against pseudomonas?
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cefipime
ceftriaxone cefoperazone |
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which ceph has the longest half life?
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rocephin/ceftriazone
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you have a true penicillin allergic patient and you discover they have a gram negative infection what can you use?
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aztreonam
esty calls it the "uselss drug" |
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what class has the broadest spectrum of all beta lactams and lowers the seizure threshold?
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Carbapenems: primaxin
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what is the normal trough for p on vanco?
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10-15
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what are the 3 situations when it is ok for your patients troughs on vanco to be 15-20?
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new site (lungs)
endocarditis septic p in ICU with multiple organ failure |
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what is the MOA of vanco?
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inhibits cell wall synthesis
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what is the dosing for VANCO?
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15mg/kg q 12 (crcl >50)
q 24 if crcl<50 |
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your patient is on vanco. he begins to complain of tinnitis. what do youdo?
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stop vanco stat.
do not rechallenge. start patient on nalizolie = zybox |
