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37 Cards in this Set

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  • Back
what are the majority of CAP's caused by?
strep
what is the causative agent in the majority of cellulitis?
staph
DOC for febrile neutropenia?
4th gen : CEFEPIME
doc to treat staph infection?
(usually cellulitis)
ANCEF (cefazolin) 1st gen
doc for pseudomonas?
big gun= zosyn IV (piperacillin beta lactamase inhibitor combo)
doc for legionaire's?
erythromycin
doc for CAP?
macrolide; erythromycin
which drugs' MOA inhibits the bacterial synthesis of folic acid?
sulfanamides
which big gun causes "red man syndrome"
vanco
DOC for legionella?
zithromax/Azithromicin: macrolide
what is an alternative drug for HIV p to use if they have an allergy to bactrim?
Dapsone
what are some AE to sufanamides?
SJS
hemolytic anemia
hypoglycemia
jaundice
kernicterus (neonates)
agranulocytosis
due to the metabolism of the sulfanamides which particular population are they good for?
metabolized by acetylation: good for the elderly
what is the DOC for pregnant fe with UTI?
macrodantin
what drug is used for the prophylaxsis of PCP in hiv patients?
TMP
what are some uses for TMP?
it is a sulfanamide:
UTI
salmonella
burns
PCP prophylaxsis
what is the MOA of penicillins?
inhibit the synthesis of the cell wall
what can you use for pregnant female with cellulitis?
keflex/Cephalexin 1st gen
what class of abx is considered the anti-staphylococcal penicillins?
the CONDM drugs:
cloxacillin
oxacillin
nafcillin
dicloxacillin
methicillin
what are the anti-pseudomonal penicillins?
ticarcillin
piperacillin
carbecillin
doc for pseudomas?
piperacillin + aminoglycoside for double coverage
what bugs are the 1st gen ceph's good for?
PEK
Preoteus mirabilis
E.coli
Klebsiella
two examples of 1st gen?
cephalexin/keflex
cefadroxil/Duracef
what bugs are the 2nd gen ceph's good for?
HEN PEK
PEK +
H.flu
enterobacter
Neisseria
name 3 2nd gen ceph's that cover anerobes?
metal tan fox!
cefmetazole
cefotetan
cefoxitin
what are 3 common diseases Rocephin is used to treat?
lyme disease
gonorrhea
CAP
meningitis
what bugs are 3rd gen ceph's good to treat?
PEEK, some HEN
Proteus
E.coli
enterobacter
klebsiella
common ceph to cross the BBB?
cefipime
what are the 3 ONLY effective agents against pseudomonas?
cefipime
ceftriaxone
cefoperazone
which ceph has the longest half life?
rocephin/ceftriazone
you have a true penicillin allergic patient and you discover they have a gram negative infection what can you use?
aztreonam
esty calls it the "uselss drug"
what class has the broadest spectrum of all beta lactams and lowers the seizure threshold?
Carbapenems: primaxin
what is the normal trough for p on vanco?
10-15
what are the 3 situations when it is ok for your patients troughs on vanco to be 15-20?
new site (lungs)
endocarditis
septic p in ICU with multiple organ failure
what is the MOA of vanco?
inhibits cell wall synthesis
what is the dosing for VANCO?
15mg/kg q 12 (crcl >50)
q 24 if crcl<50
your patient is on vanco. he begins to complain of tinnitis. what do youdo?
stop vanco stat.
do not rechallenge.
start patient on nalizolie = zybox