Pharm Ii - Firstaid(Tm) Pharmacology For Psych

Front 1

these are the typical antipsychotics

Back 1

haloperidol, thioridazine, fluphenazine, chlorpromazine

Front 2

these drugs block D2 receptors

Back 2

typical antispychotics

Front 3

these are the low potency neuroelptics and therefore have non-neurologic side effects

Back 3

thioridazine, chlorpromazine

Front 4

these are the high potency neuroleptics and have neurologic sides effects

Back 4

haloperidol, trifluoperazine

Front 5

neuroleptics are used to treat these conditions

Back 5

schizophrenia, psychosis, acute mania, Tourrette's

Front 6

these are the side effets of neuroleptics

Back 6

EPS side effects, endocrine side effects (hyperprolactinemia); side effects arise from blocking muscarinic (constipation), alpha adrenergic (hypotension) and histamine (sedation) receptors as well

Front 7

these are the EPS side effects

Back 7

4 h: acute dystonia, 4d: akinesia, 4 wk: akathisia, 4 mo: tardive dyskinesia

Front 8

akathisia

Back 8

restlessness

Front 9

akinesia

Back 9

parkinsonian sx

Front 10

tardive dyskinesia

Back 10

sterotypic oral-facial movements due to DA receptor sensitization, seen in long-term antipsychotic use

Front 11

these are the atypical antipsychotics

Back 11

clozapine, olanzapine, risperidone, quetapine, aripiprazole, ziprasidone (it is not aTYPICAL for an OLd CLOset to RISPER)

Front 12

these drugs block 5HT2 and DA receptors

Back 12

atypical antipsychotics

Front 13

this drug is used for schizophrenia, OCD, anxiety disorder, depression, mania and Tourette's

Back 13

olanzapine

Front 14

this drug may cause agranulocytosis

Back 14

clozapine (atypical antipsychotic)

Front 15

these are the side effects of lithium

Back 15

tremor, polyuria, hypothryoidism, teratogenesis (LMNOP: Lithium, Movement, Nephrogenic diabetes insipidis, hypOthyroidism, Pregnancy problems)

Front 16

uses of lithium

Back 16

mood stabilizer in BPAD, blocks manic attacks

Front 17

this drug stimulates 5HT1A receptors

Back 17

buspirone

Front 18

buspirone is this type of drug

Back 18

anxiolytic

Front 19

buspirone is used to treat this disorder

Back 19

GAD

Front 20

this anxiolytic is advantageous bc it does not cause sedation or addiction, and does not interact w EtOH

Back 20

buspirone

Front 21

these are the SSRI's

Back 21

fluoxetine, sertraline, paroxetine, citalopram

Front 22

these are the two main disorders that SSRI's are used to treat

Back 22

depression, OCD

Front 23

these are the side effects of SSRI's

Back 23

fewer than TCA's, includes GI upset, sex dysfunction (anorgasmia)

Front 24

these two classes of anti-depressants should not be combined bc of risk of serotonin syndrome

Back 24

SSRI's and MAOI's

Front 25

serotonin syndrome

Back 25

hyperthermia, muscle rigidity, CV collapse

Front 26

TCA's are used to treat these disorders

Back 26

MDD, bedwetting (imipramine), OCD (clomipramine, but SSRI's are better for OCD)

Front 27

these are the side effects of TCA's

Back 27

sedation, alpha blocking effects (hypotension), atropine-like side effects (tach, urinary retention)

Front 28

these TCA's have more anticholinergic side effects than others

Back 28

tertiary TCA's, amitriptyline

Front 29

this TCA is the least sedating of TCA's

Back 29

desipramine

Front 30

TCA overdose results in…

Back 30

Tri-C's: convulsions, coma, cardiotoxicity (arrhtyhmia); resp depression, hyperpyrexia; confusion and hallucinations in the elderly (use nortriptyline)

Front 31

this TCA has less anticholinergic side effects

Back 31

nortriptyline

Front 32

these are the non-SSRI, non-TCA, non-MAOI antidepressants

Back 32

bupropion, venlafaxine, mirtazapine, maprotiline, trazodone ("you need BUtane in your VEINs to MURder for a MAP of alcaTRAZ")

Front 33

this antidepressant is used in smoking cessation

Back 33

bupropion

Front 34

these are the toxicities of buproprion

Back 34

stimulant effects (tach, insomnia), HA, sz in bulimic pts

Front 35

this antidepressant is notable bc it does not cause sexual side effects

Back 35

bupropion

Front 36

these drugs are used to treat atypical depression

Back 36

MAOI's

Front 37

this SNRI is used to treat GAD as well as depression, and may be useful for analgesia as well

Back 37

venlafaxine

Front 38

these are the toxicities of venlafaxine

Back 38

stimulant effects (tach, insomnia, incr BP), sedation, nausea, constipation

Front 39

this antidepressant is an alpha-2-adrenergic antagonist (increasing NE and 5HT release), and a potent 5HT2 and 5HT3 receptor antagonist

Back 39

mirtazapine

Front 40

this antidepressant is a non-TCA that blocks NE reuptake

Back 40

maprotiline

Front 41

mechanism of TCA's

Back 41

block NE and 5HT reuptake

Front 42

most of the side effects of TCA's probably are due to this action, and that is why SSRI's have less side effects

Back 42

blocking of NE reuptake

Front 43

these are the toxicities of maprotiline

Back 43

sedation, orthostatic hypotension

Front 44

trazodone works by this mechanism

Back 44

block 5HT reuptake

Front 45

this drug has as a toxic side effect priapism

Back 45

trazodone

Front 46

these are the MAOI's

Back 46

phenelzine, tranylcypromine

Front 47

this class of antidepressant is a also used to treat axiety and hypochondriasis

Back 47

MAOI's

Front 48

these are the toxicities of MAOI's

Back 48

hypertensive crisis with tyramine ingestion and beta agonists, and CNS stimulation

Front 49

these drugs are used to treat ADHD

Back 49

amphetamine, methylphenidate

Front 50

this drug increases NE release

Back 50

methylphenidate

Front 51

this drug is used to treat narcolepsy, obesity, and ADHD

Back 51

amphetamine

Front 52

mechanism of action of amphetamine

Back 52

releases stored catecholamines