Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
14 Cards in this Set
- Front
- Back
|
Partial seizure, simple
|
consciousness preserved; psychic symptoms, autonomic dysfunction; convulsive jerking and tingling
|
|
|
Partial seizure, complex
|
impaired consciousness; psych sympt.
|
|
|
Tonic-clonic seizure, generalized
|
loss of consciousness; muscle rigidity & resp arrest (tonic phase) --> jerking and incontinence (clonic phase)
|
|
|
absence seizures, generalized
|
impaired consciousness, brief, begins in childhood and done by 20 years
|
|
|
myoclonic seizure
|
single of multiple myoclonic jerks
|
|
|
status epilepticus
|
series of seizures w/o regain of consciousness. Medical emergency.
|
|
|
Drugs for partial and generalized tonic-clonic seizures: mnenomic
|
My AMAZING FUN TOY VALENTINE
Carbamazapine Phenyltoin Valproic acid |
|
|
Phenytoin: Mech, spectra of activity and SE
|
Blockade of Na+ channels strongest effect
nystagmus early, diplopia, ataxia, gingival hyperplasia eliminated by liver: must increase dose gradually |
|
|
Carbamazepine: Mech, spectra of activity and SE
|
Blockade of Na+ channels
diplopia, ataxia, blood dyscrasias, steven-johnson synd rare but serious |
|
|
Valproic acid
|
efficacious against like all seizures
blockade of Na+ channels? GABA? Se: hepatotoxicity (rare but serious) |
|
|
Drugs used against generalized (absence) seizures mnenomic
|
CLAIRE VALLIN SUX EtOH
Clonazapam Valproic Acid Ethosuximide |
|
|
Ethosuximide
|
absence seizures ONLY
T-type channel MOA Good absorption SE: gastric distress, rashes |
|
|
Clonazepam
|
best for absence seizure
typical benzo SE of sedation, development of tolerance, withdrawl |
|
|
Tx of staticus epilepticus
|
iv diazepam followed by iv fosphenytoin or phenylbarbital (Watch for synergistic CNS depression)
|
