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57 Cards in this Set

  • Front
  • Back
parasympathetic
craniosacral
sympathetic
thoracolumbar
parasymp NT
Ach (nicotinic)
symp NT
NE (adrenergic)
Ach (muscarinic)
Dompamine (dopaminergic)
Ganglionic
Ach (nicotinic)
NE synthesis
Tyrosine - dopa - dopamine-
norepinephrine
fate of NT
enzymatic breakdown
re-uptake
effects of parasym
stimulation
non-vascular smooth muscle
contract
sphincter relax
pupil constrict/increased exocrine gland secretion
causes of increased parasym activity
choline receptor stimulation
decrease breakdown Ach
direct acting choline recep.
agonists
choline esters
alkaloids
Choline esters
Bethanechol (Urecholine)
Carbachol (Isopto-carbachol)
Bethanechol use of and adm
tx urinary retention s/p anesthesia
SQ, oral
Carbacol use and adm
tx glaucoma; opthalmic only
alkaloids
nicotine

pilocarpine
pilocarpine use and adm
tx glaucoma; opthal soln
indirect-acting
cholinomimetics
cholinesterase inhibitors
reversible cholinesterace
inhibitors
pyridostigmine
physostigmine
neostigmine
edrophonium
irreversible cholinesterase
inhibitors
organophosphates
clinical use of indirect-
acting cholinomimetics
myasthenia gravis
glaucoma (2nd/3rd line)
tx of organophosphate
poisoning
atropine (relieve sx)

pralidoxime (regenerates
cholinesterace)
effects of cholinoreceptor
blockers (anticholinergics)
dec. contract non-vas smooth
muscle
sphincter contraction
dec exocrine gland secr
pupil dilation
increased HR
cholinoreceptor blockers
propantheline bromide
(Pro-Banthine)
Atropine, Glycopyrrolate (Robinul)
Tropicamide (Mydriacyl),
Homotripine
dicyclomine (Bentyl)
Belladonna (Donatol)
Benztropine (Cogentin)
Ipratropium Bromide (Atrovent
Scopolamine
Propantheline bromide
GI (stop diarrhea)
urinary urgency
atropine
Glycopyrrolate (Robinul)
pre-anesthesia med
(dec tracheal secretion)
inc HR in those with heart
block (bradycardia)
Tropicamide (Mydriacyl)
Homatripine
dilation of eye
dicyclomine (Bentyl)
Belladonna (Donatol)
GI cramping (stops)
Benztropine (Cogentin)
parkinson's dz
Ipratropium Bromide
(atrovent)
asthma, COPD
Scopolamine
motion sickness
Cholinoreceptor blocker
side effects
dry mouth
urinary retention
constipation
blurry vision (pupil dilation
tachycardia
sympathetic receptors
alpha 1, 2
beta 1, 2, 3
dopaminergic
alpha 1 stimualation effects
vasoconstriction
alpha 1 receptors are found
post-synaptic smooth muscle
alpha 1 antagonism (blocking)
vasodilation
beta 1 receptors are found
heart
beta 1 stimulation effects
increase HR (+ chronotropic)
incr. contractility
(+ inotrophy)
beta 1 antagonism (blocking)
dec HR and contractility
Beta 2 receptor location
vascular and non-vascular
smooth muscle
broncho/tracheal tree
beta 2 stimulation
relaxation of smooth muscle
beta 2 antagonism
constriction of smooth muscle
(dyspnea)
alpha 2 receptor location
pre-synaptic terminal
alpha 2 receptor stimulation
dec NT release and activity
at other adrenergic neurons
alpha 1 agonists
phenylephrine (neo-syneph)
naphazoline (privine)
alpha 1 antagonists
prazosin (minipress)
terazosin (hytrin)
doxazosin (cardura)
alpha 1 antagonism SE
hypotension
syncope
dz treated by alpha 1
antagonists
htn
begnin BPH
alpha 2 agonists
clonidine (Catapres) po, top
htn, hotflashes, opiate
withdrawl
methyldopa (aldomet) po, IV
pregnancy induced htn
alpha 2 agonist SE
sedation
depression
sexual dysfxn
beta 1 specific agonist
dobutamine (dobutrex) IV only
incr. rate, contract, outp
beta 2 specific agonist
albuterol (proventil)
terbutaline (Brethine)
preterm labor
ritodrine (Yutopar)IV
uterine relaxation
non specific beta agonists
Isoproterenol (Isuprel)

Metaproterenol (alupent)
non-specific beta agonists
SE
tachycardia
anxiety
tremors
specific beta 1 antagonists
atenolol (tenormin)
metoprolol (Lopressor)
Esmolol (Brevibloc)
dec. HR, BP
nonspecific beta antangonists
propranolol (inderal)
nadolol (Corgard)
Timolol (Timoptic) glaucoma
SE of beta antagonists
1st pass effect
diabetes (hypoglycemia)
lipids (increase cholesterol)
asthma (bronchospasm)
adrenergic agonists
NE (alpha and beta)
dompamine (Intropin)
low dose-dopam recept
high dose-const adrenal/mes
mixed antangoists
labatelol (trandate)
dec HR, BP
carvedilol (Coreg) more beta