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20 Cards in this Set
- Front
- Back
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A drug that is purified from urine of postmenopausal women and used to promote spermatogenesis in infertile men?
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Urofollitropin, which is used to provide FSH activity
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A 29 y.o. woman in her 41st week of gestation had been in labor for 12 h. Although her uterine contractions had been strong and regular initially, they had diminished in force during the past hour. To facilitate this woman's labor and delivery, she would be treated with?
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Oxytocin
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A 3 y.o. boy with failure to thrive and metabolic disturbances was found to have an inactivating mutation in the gene that encodes the growth hormone receptor. The drug that is most likely to promote improve metabolic function and promote his growth is?
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Mecasermin, which is a combination of recombinant IGF-1 and the binding protein that protects IGF-1 from immediate destruction.
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An important difference between leuprolide and ganirelix is that ganirelix ?
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Immediately reduces gonadotropin secretion. Leuprolide is an agonist of GnRH receptors, whereas ganirelix is an antagonist. Both drugs can be used to inhibit gonadotropin release.
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A 27 y.o. woman with amenorrhea, infertility and galactorrhea was treated with a drug that successfully restored ovulation and menstruation. Before being given the drug, the woman was carefully questioned about previous mental health problems, which she did not have. She was advised to take the drug orally. The drug used to treat this Pt was probably?
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Bromocriptine, a dopamine receptor agonist. PTs with a history of schizophrenia or other psychotic illness should not be given this drug.
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Who i likely to be treated with somatropin?
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Promotes growth in children with Turner's syndrome (an XO genetic genotype) or chronic renal failure. It also helps combat the AIDS-associated wasting syndrome.
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A 3 y.o. girl presented with hirsuitism, breast enlargement, and a height and bone age that was more consistent with an age of 9. Diagnostic testing revealed precocious puberty. The most appropriate drug treatment is?
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Leuprolide, a long acting GnRH agonist
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A 47 y.o. man exhibited signs of symptoms of acromegaly. Radiologic studies showed the presence of a large pituitary tumor. Surgical treatment of the tumor was only partially effective in controlling his disease. At this point, which of drug is most likely to be used as pharmacologic therapy?
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Octreotide, which reduces excess GH production.
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A 37 y.o. woman with infertility due to obstructed fallopian tubes was undergoing ovulation induction in preparation for in vitro fertilization. After 10 days of treatment is most likely to involve 10 - 14 days of treatment with?
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Follitropin. STEPS involved: • 1), endogenous gonadotropin production is inhibited either by GnRH antagonist or agonist; 2) follicle development is driven via FSH; 3) oocyte maturation is induced via LH or LH human chorionic gonadotropin (hCG)
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A 7 y.o. boy underwent successful chemotherapy and cranial radiation for treatment of acute lymphocytic leukemia. One month after the completion of therapy, the PT presented with excessive thirst and urination plus hypernatremia. Laboratory testing revealed pituitary diabetes insipidus. To correct these problems, this PT is likely to be treated with?
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Desmopressin, na peptide agonist of vasopressin V2 receptor.
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Somatostatin (SRIF) analog used for acromegaly, carcinoid, glucagonoma and other GH producing pituitary tumors
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Octreotide
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Somatotropin (GH) analog used in GH deficiency (dwarfism)
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Somatrem
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GHRH analog used as diagnostic agent
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Sermorelin
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GnRH agonist used for infertility or different types of CA depending on pulsatile or steady usage respectively
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Leuprolide
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GnRH antagonist with more immediate effects, used for infertility
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Ganirelix
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Dopamine (DA) agonist (for Parkinson's disease), used also for hyperprolactinemia
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Bromocriptine
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Hormone inhibiting prolactin release
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Dopamine
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ACTH analog used for diagnosis of patients with corticosteroid abnormality
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Cosyntropin
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Synthetic analog of ADH hormone used for diabetes insipidus and nocturnal enuresis
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Desmopressin (DDAVP)
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SE of oral contraceptive pill
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Increased thromboembolic events
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