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12 Cards in this Set
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*inhalation for asthma
*ophthalmic for allergy *nasal for allergy *oral for food allergy |
Cromolyn sodium
pharm- inhibit mast cell degran moa-*Inhibit mast cell degranulation by preventing inc in intracellular Ca 2+ conc caused by the formation of IgE bridges |
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*Ophthalmic for allergy
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Olopatadine
"olo"~"ojo" (eye in Spanish) pharm- inhibit mast cell degran Inhibitors of mast cell degranulation |
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adjunctive therapy for acute hypersensitivity rxns & for nausea & vomiting
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H1-Receptor Blockers (Antihistamines)
“—amine” Brompheniramine, po Chlorpheniramine, po Diphenhydramine, po “—adine” Fexofenadine, po Desloratadine, po Olopatadine, eye drops Loratadine, po Cyproheptadine, po "--azine, “—izine” Cetirizine, po Meclizine, po Hydroxyzine, po Promethazine, IM or suppository Dimenhydrinate, po *Keeton: Never use H1 blockers to Tx otitis media |
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adjunctive therapy for acute hypersensitivity rxns & for nausea & vomiting IN TRUCK DRIVERS
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the new antihistamine
-fexofenADINE -loratADINE -desloratADINE -cetirizine |
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pharm effects of H1-blockers
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*H1 receptor blockade:
-prevents constrictor response to histamine @ most smooth muscle (bronchial & GI) -inhibit pain & itching caused by histamine at sensory nerve endings -antagonize in cap permeability *Cholinergic muscarinic blockade: -depresses CNS (sedation, etc) -inhibits nasopharyngeal secretion -prevents motion sickness (action in vestibular nuclei) *Local anesthetic effect (diphenhydramine only!) *Exerts antiemetic effect: Promethazine Hydroxyzine Dimenhydrinate Diphenhydramine |
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*Parkinson’s dz
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diphenhydramine
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*Prophylaxis for motion sickness
*Vertigo (Meniere’s dz) |
dimenhydrinate
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"2 men with vertigo"
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*Seasonal & allergic rhinitis
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Loratidine
Cetirizine |
"Lora's cat (cet) has bad allergies"
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*Treatment for motion sickness
*Pre-op sedation *acute hypersensitivity rxns *Allergic dermatoses *motion sickness *sedate anxious pts *prevent post-op N/V *N/V assoc w/ GI infection |
Promethazine
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*gastric & duodenal ulcers
*GERD *prevent stress ulcers precipitated by severe trauma *anaphylaxis *viral warts & other skin lesions |
Fomotidine
*Block H2 receptors |
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migraine headache
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Use a "triptan"
(*sumatriptan, almotriptan) Sumatriptan moa-*selective agonist at 5HT 1B/1D receptors *Migraine headaches -Sumatriptan has short half life (2h) so HA may reoccur after single dose therapy -if pts don’t respond well to initial dose, then giving more will not likely be beneficial *Cluster HA -Sumatriptan severity of pain -Sumatriptan decreases functional disability & decreases ipsilateral conjunctival injection |
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carcinoid syndrome
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1.Cyproheptadine=DOC
pharm--GI hypermotility, hypersecretion & Diarrhea moa-*Blocker at 5HT1 & 5HT2 receptors *Blocker at H1-histamine & muscarinic receptors 2. Octreotide *somatostatin agonist-->Inhibits release of serotonin from tumor cells |
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