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36 Cards in this Set
- Front
- Back
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Antacids?
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NaHCO3 = bad for CHF
CaCO3 = kidney stones AlOH = constipation MgOH = diarrhea, #1 antacid |
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#1 antacid?
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MgOH
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Cytoprotective anti-peptic drugs?
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Sucralfate
Bismusth (pepto, black stools) Misoprostol (PGE analogue) |
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Anti-secretory peptic drugs?
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H2-blockers = cimetidine, rantidine
Anti-muscarinics= dicyloamine PPI's = "-prazole" |
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Blocks 100% of H+ secretion from parietal cell?
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Protono-pump inhibitors, omeprazole
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#1 for Zollinger-Ellison Syndrome and GERD?
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Omeprazole (ppi)
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Most potent antifungal? Mechanism?
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Amphotericin B, binds to sterols and forms pores. (macrolide)
NO RESISTANCE |
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Topical macrolide?
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Nystatin, similar to ampho B, but topical.
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Anti-fungal that inhibits DNA/RNA synthesis?
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Flucytosine
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Inhibit's ergosterol synthesis?
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Azoles and Terbinafine
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#1 drug for cryptococcal meningitis?
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fluconzaole (only azole to cross BBB)
also flucytsosine + ampho B |
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#1 drug for persistent dermatophytic infection?
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itraconazole
only antifungal that is active against all aspergillis forms |
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Anti-fungal used for Cushings?
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Ketoconazole
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Topical azole?
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Miconazole
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Tx's insomnia, pruritis, and motion sickness?
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diphenhydramine (1st gen anti-H)
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anti-histamine with no sedation?
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2nd gen, loratadine (TREMORS)
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#1 ORAL STEROID?
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prednisone, best bioavailability of adrenal steroids
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#1 steroid, used for everything?
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hydrocortisone
Namely cushing's, see inc. WBC, protein breakdown, and thin skin and ulcers. |
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Steroid used to treat arthritis, injected into joint?
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methyprednisone
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Steroid used in Asthma?
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dextramethasone
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Side effects of 1st gen anti-histamines?
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orthostatic htn, sedations, xerostomia, constipation
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1st gen anti-histamines?
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dephenhydramine (allergies)
meclizine (motion sickness) chlorpheniramine (least side effects) |
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Difference b/n 1st and 2nd gen anti-H's?
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Both block H1 receptor, but 1st displays ACh antagonism also
2nd = longer duration of action, H-1 specific, no cholinergic effects NO SEDATION, NO DRY MOUTH |
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2nd gen anti-H's?
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loratidine = ALLERGIES
terfenadine = arrythmias certinazine foxofenadine aztemizol |
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Mechanism of nasal decongestants?
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vasoconstrict via alpha-1 agonist = ephedrine/psuedoephedrine
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Anti-tussive's?
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Opiates = codiene, dextromethorpha
non-opiates: carbetapentane peripheral acting: benzonatate |
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Inhibits mast cell degranulation?
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cromolyn
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Tx for mild asthma?
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short acting B2-agonists: albuterol, metaproterenol, terbutaline, isoproterenol
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Tx for more severe asthma?
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long acting B2-agonist = salmeterol
AND steroid (dextramethasone) |
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Leukotriene receptor antagonists?
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Zafirulukast, Montelukast
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Lipoxegenase inhibitor?
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Zileuton
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1st line Tx for TB?
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Isoniazid, rifampin, ethambutol, pyrazinamide
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orange urine?
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rifampin, also orange sweat and tears
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TB prophylaxis?
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Isoniazid
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Use for MDR-TB?
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amikacin
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Used to Tx MAC in AIDS?
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rifabutin
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