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30 Cards in this Set

  • Front
  • Back
antacids work by
neutralizing stomach acid
2 common antacids
MgOH2, AlOH3
Tox of MgOH2
constipation
tox of AlOH3
diarrhea
Prototype H2x for PUD
cimetidine
PPI end in
prazole
why do PPI work best?
irreversibly inactivate parietal H/K ATPase
tox of chronic PPI use 3
hypergastrinemia, B12 def, interact with Rx absorption
mech of sucralfate
coats ulcers
tox of sucralfate
virtually nada (it's insoluble and excreted)
prevention of PUD in pt on chronic NSAID Tx
misoprostol
bismuth mech 4
coats ulcers, stim mucosal protection, antimicrobial, sequesters enterotoxins
tox assoc w/ bismuth
black stools
Eradication of h. pylori? 2
PPI + bismuth/tetracycline/metronidazole or amox + clarithromycin
muscarinic agonist used to promote motility
neostigmine
dopa antagonists used to promote motility
metoclopramide
dopa antagonists used for antiemesis
metoclopramide
5HT antagonists used for antiemesis 2
setrons, phenothiazine
H1 antagonists used for antiemesis
diphenhydramine
antimuscarinic used for antiemesis
scopolamine
steroid used for antiemesis
dexamethasone
NK1-R antagonist used for antiemesis
Aprepitant
tox of aprepitant
substrate & inh CYP3A4
severe IBS with diarrhea is Tx with
alosetron
IBS with constipation is Tx with
tegaserod
Rx for IBD
aminosalicylate, steroid, etc
what is pancreatin?
panc lipase from pigs
3 mech for laxatives
bulk-forming, softening, lubricating
most important CNS Rx for diarrhea 2
diphenoxylate, loperamide
Rx that inh gallstone formation 2
chenodiol, ursodiol