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30 Cards in this Set
- Front
- Back
antacids work by
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neutralizing stomach acid
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2 common antacids
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MgOH2, AlOH3
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Tox of MgOH2
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constipation
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tox of AlOH3
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diarrhea
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Prototype H2x for PUD
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cimetidine
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PPI end in
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prazole
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why do PPI work best?
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irreversibly inactivate parietal H/K ATPase
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tox of chronic PPI use 3
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hypergastrinemia, B12 def, interact with Rx absorption
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mech of sucralfate
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coats ulcers
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tox of sucralfate
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virtually nada (it's insoluble and excreted)
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prevention of PUD in pt on chronic NSAID Tx
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misoprostol
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bismuth mech 4
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coats ulcers, stim mucosal protection, antimicrobial, sequesters enterotoxins
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tox assoc w/ bismuth
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black stools
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Eradication of h. pylori? 2
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PPI + bismuth/tetracycline/metronidazole or amox + clarithromycin
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muscarinic agonist used to promote motility
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neostigmine
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dopa antagonists used to promote motility
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metoclopramide
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dopa antagonists used for antiemesis
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metoclopramide
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5HT antagonists used for antiemesis 2
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setrons, phenothiazine
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H1 antagonists used for antiemesis
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diphenhydramine
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antimuscarinic used for antiemesis
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scopolamine
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steroid used for antiemesis
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dexamethasone
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NK1-R antagonist used for antiemesis
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Aprepitant
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tox of aprepitant
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substrate & inh CYP3A4
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severe IBS with diarrhea is Tx with
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alosetron
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IBS with constipation is Tx with
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tegaserod
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Rx for IBD
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aminosalicylate, steroid, etc
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what is pancreatin?
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panc lipase from pigs
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3 mech for laxatives
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bulk-forming, softening, lubricating
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most important CNS Rx for diarrhea 2
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diphenoxylate, loperamide
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Rx that inh gallstone formation 2
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chenodiol, ursodiol
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