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38 Cards in this Set

  • Front
  • Back
What are the two major cerebral centers?
chemoreceptor trigger zone (CTZ) near medulla
vomiting center- medulla

these cause vomiting when stimulated
CTZ is stimulated by which neurotransmitter?
dopamine
nonprescription antiemetics
Antihistamines- Benadryl
Pepto Bismol
How does Benadryl work?
prevents nausea, vomiting, and dizziness (vertigo) caused by motion by inhibiting vestibular stimulation in the middle ear
How does Pepto-Bismol work?
acts directly on the gastric mucosa to suppress vomiting

considered an absorbant because it absorbs bacterial toxins
also commonly used for travelers diarrhea
Prescription Antiemetics
Vistaril
Phenergan
Ativan
Zofran
Kytril
Reglan
Compazine
dopamine antagonists (phenothyazines)
Compazine and Phenergan

block dopamine receptors in CTZ

dry mouth, drowsiness, decreased secretions
Seratonin Receptor Agonists
Zofran and Kytril

block the serotonin receptors in CTZ and afferent vagal nerve terminals in the upper GI tract

they DONT block dopamine receptors --> no EPS

headache, diarrhea, dizziness, fatigue
Glucocorticoids
Decadron

suppress emesis assciated with cancer chemo

administered IV for a short time , less side effects
Cannabinoids
active ingredients in marjuana
not for clients with psych disorders
appetite stimulant
causes euphoria
Emetics
Ipecac
Amorphine
Charcole
Ipecac
for any ingestion non-caustic
taken with water, not milk or carbonated beverages
vomiting 15-30 minutes after

over use causes cardiomyopathy, ventricular fibrillation, death
charcoal
promotes absorption of poison or toxic substances
not systemically absorbed
used for poisoning
Apomorphine
IV, stimulates vomiting
only with conscious patients
opiates
increase intestinal motility by decreasing peristalsis
cause CNS depression when taken with alcohol , sedatives, or tranquilizers
Lomotil
opiate that has less potential for drug dependence
used for travelers diarrhea
Imodium
OTC
protects against diarrhea
reduces fecal volume
decreases intestinal fluid and electrolyte losses
Osmotic Laxatives
pull water into the colon and increase water in the feces to increase bulk, which stimulates peristalsis
high doses are used for diagnostic or surgical procedures
GoLYTELY
Used before procedures like colonoscopy
can be used by clients with renal impairment or cardiac disorder
Stimulants
Dulcolax
Bisacodyl
Castor Oil
Dulcolax
Short term constipation treatment
bowel preparation for diagnostic tests
can cause tetany

not with apendicitis
Bisacodyl
harsh cathartig or purgative
for bowel preparation for diagnostic tests
Bulk-Forming Laxatives
natural fibrous substances that promote large, soft stools by absorbing water into the intestine, increasing fecal bulk and peristalsis
need to take with water
does not cause dependence
Metamucil
first line agent
need enough water
Nursing Interventions for Bulk Forming
check fluid intake and output
monitor bowel sounds
identify the cause of constipation
Emollients
stool softeners to prevent constipation
lower surface tension and promote water accumulation in the intestine and stool
frequently for MI patients or surgery so they dont strain
Nursing Implications for stimulant laxatives
monitor fluid intake and output
note signs and symptoms of electrolyte imbalance
take drug only with water
dont take within 1 hour of another drug
Colace & Peri-Colace
Peri-colace has senna
used episodically or routinely
Predisposing Factors in Peptic Ulcer Disease
mechanical disturbances
genetc influences
bacterial organisms
environmental factors
certain drugs
GERD
inflammation or erosion of the esophageal mucosa caused by a reflux of gastric acid content from the stomach into the esophagus
-smoking and obesity accelerate the disease process
Robinul
anticholenergic
dries secretions
taken before meals to decrease acid secretion that occurs with eating
act by inhibiting ach and blocking histamine and HCl
delay gastric emptying time- more used for duodenol ulcers
antacids
promote ulcer healing by neutralizing Hcl and reducing pepsin activity- they do not coat the ulcer
Tums
dont take with other meds, hydration is important
calcium carbonate
Alyminum hydroxide
causes constipation
Mylanta
dont take with other meds, hydrate
magnesium hydroxide and aluminum hydroxide`
Carafate
pepsin inhibitor
coats the stomach
do not give with other medications because it will stop the absorption of others
Zantac
H2 blocker antiulcer
blocks histamine response and decreases blood flow
Prevacid
Proton Pump inhibitor
decreases gastric acid