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18 Cards in this Set

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sucralfate
protect GI, critically ill patients, prevent bleeding from stress related gastritis
misoprostol
protect GI, prostaglandin anaglog, increases mucosal blood flow, stimulates mucus and bicarb, used to prevent NSAID associated ulcers
bismuth
protect GI, travelers diarrhea, h pylori, acute diarrhea, binds ulcer base providing protection and allowing HCO3 to increase
metoclopramide, domperidone
5HT4 increases Ach release and is prokinetic, dop2 antagonist has antinausea effects, have extrapyramidal Ses, used for GERD, post surgery, antinausea
cisapride
not used anymore b/c torsades
laxation
evacuate formed material
catharsis
evacuate unformed material
bulk agent
methyl cellulose, absorb water so take with water,
fecal softeners
docusate, absorbs water and lipids
osmotic laxatives
mgo, sorbital, increase fecal fluidity, mgo for acute, sorbital for chronic
stimulant laxatives
aloe, sennae, increase peristalsis
antidiarrheal
loperamide, lomotil… opiods, loperamide doesn't cross BBB
IBS
mgo or loperamide or amitryptaline for pain… for unresponsive cases use alonsetron which is 5HT3 antag, can cause GI toxicity and ischemia
ulcerative colitis
mild/mod use sulfasal, severe use glucocorticoids and azathioprine / 6 mercaptopurine
crohns
mild use sulfa, moderate use glucocorticoids, severe use azithroprine / 6 MP, also can use methotrexate
vomiting, vagal
ondansetron, only vagal vomiting, 5HT3 antagonist, prolonged QT
migraine postsurgical nausea
phenothiazines D2 antagonist
motion sickness
diphenhydramine, meclizine, H1 antagonist