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18 Cards in this Set
- Front
- Back
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sucralfate
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protect GI, critically ill patients, prevent bleeding from stress related gastritis
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misoprostol
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protect GI, prostaglandin anaglog, increases mucosal blood flow, stimulates mucus and bicarb, used to prevent NSAID associated ulcers
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bismuth
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protect GI, travelers diarrhea, h pylori, acute diarrhea, binds ulcer base providing protection and allowing HCO3 to increase
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metoclopramide, domperidone
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5HT4 increases Ach release and is prokinetic, dop2 antagonist has antinausea effects, have extrapyramidal Ses, used for GERD, post surgery, antinausea
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cisapride
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not used anymore b/c torsades
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laxation
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evacuate formed material
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catharsis
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evacuate unformed material
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bulk agent
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methyl cellulose, absorb water so take with water,
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fecal softeners
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docusate, absorbs water and lipids
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osmotic laxatives
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mgo, sorbital, increase fecal fluidity, mgo for acute, sorbital for chronic
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stimulant laxatives
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aloe, sennae, increase peristalsis
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antidiarrheal
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loperamide, lomotil… opiods, loperamide doesn't cross BBB
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IBS
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mgo or loperamide or amitryptaline for pain… for unresponsive cases use alonsetron which is 5HT3 antag, can cause GI toxicity and ischemia
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ulcerative colitis
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mild/mod use sulfasal, severe use glucocorticoids and azathioprine / 6 mercaptopurine
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crohns
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mild use sulfa, moderate use glucocorticoids, severe use azithroprine / 6 MP, also can use methotrexate
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vomiting, vagal
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ondansetron, only vagal vomiting, 5HT3 antagonist, prolonged QT
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migraine postsurgical nausea
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phenothiazines D2 antagonist
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motion sickness
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diphenhydramine, meclizine, H1 antagonist
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