Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
13 Cards in this Set
- Front
- Back
|
What is the major regulatory mechanism for prolactin secretion?
|
tonic inhibition by dopamine released from neurons in the median eminence of the hypothalamus
|
|
|
What do protein, peptide, and modified amino acids bind to?
|
cell surface receptors eliciting a response within the cell via second messenger pathways
|
|
|
What do steroid hormones bind to?
|
enter the cell and bind to receptors sequestered in the cytoplasm bound to heat shock proteins. They displace the HSPs and translocate to the nucleus, bind to their specific response elements and affect gene transcription.
|
|
|
How do thyroid receptors act?
|
similar to steroid receptors
|
|
|
How are protein/peptide hormones synthesized?
|
secretory vesicles
|
|
|
How are steroid hormones synthesized?
|
they are lipophilic and they cannot be stored in secretory vesicles, therefore synthesis = release
|
|
|
What does somatostatin do?
|
inhibits Growth hormone release
|
|
|
What are synthetic estrogens used for?
|
found only in combination oral contraceptives
|
|
|
What are conjugated estrogens used for?
|
hormone replacement therapy
|
|
|
What causes the vasomotor problems (headache, palpitations, night sweats, insomnia/sleep disturbances, and hot flashes) that occur in menopause?
|
increased release of LH after estrogen levels fall
|
|
|
What would you give a woman for HRT if she has had a hysterectomy?
|
no progesterone - only estrogen
|
|
|
What does estrogen only HRT cause?
|
proliferation of endometrial tissue which can lead to cancer. To prevent this, progestins are added at the end of the cycle to promote withdrawal bleeding
|
|
|
When should HRT absolutely be used?
|
in girls whom ovarian development does not occur or in women who have had their ovaries removed prior to menopausal age.
|
