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93 Cards in this Set
- Front
- Back
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drug interaction for folic acid
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phenytoin, methotrexate
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what helps the absorption of ferrous sulfate
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asorbic acid
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dosage of heparin
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1. IV 5000u, then 20-40,000u/24h
2. SC 5000u, then 8-10,000u/8h, 15-20,000u/12h |
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what is the FDA on heparin
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thrombocytopenia may show weeks after discontinue
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what is the lab test for heparin
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aPTT
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drug interaction for folic acid
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phenytoin, methotrexate
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what helps the absorption of ferrous sulfate
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asorbic acid
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dosage of heparin
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1. IV 5000u, then 20-40,000u/24h
2. SC 5000u, then 8-10,000u/8h, 15-20,000u/12h |
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what is the FDA on heparin
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thrombocytopenia may show weeks after discontinue
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what is the lab test for heparin
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aPTT
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a/e iron dextran
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HA, n/v, muscle ache, fever, anaphylaxis, pain at inj site
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administration for iron dextran
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IM z-tract, IV = slow, less than 1mL/min or 50mg/min
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dosage for warfarin
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2-10mg po qd
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lab test for warfarin
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PT and INR
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antidote for warfarin
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vit K, phytonadione
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clinical use of heparin
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rapid anticoag. & prophylaxis before high risk clotting surgeries
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nrsg considerations for heparin
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- heparin and warfarin start together, hep. gets tapered off
- assess pt for bruises and petechia |
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d/i for heparin
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aspirin
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a/e for warfarin
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bleeding (if happens, stop warfarin and give vit K)
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d/i of warfarin
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other anticoag. and aspirin
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nsg intervention for warfarin
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-assess for bruising, petechia
- given with heparin, hep gets tapered off - pt need to avoid food high in vit. K and alcohol |
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brand name for warfarin
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coumadin
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clinical use for septra
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tx PCP/PJP
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dosage for septra
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IV 20mg/kg TMP and 100mg/kg of SMX
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a/e for septra
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Gi, skin rash, erythema multiforme, steven johnson, blood dyscrasias
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precaution with septra clients
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more serious toxicity in aids pt
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which drug is 1st line therapy to treat pcp/pjp
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septra
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a/e for enfuvirtide
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local site rxn, GI, risk of pNA
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nsg consideration for enfuvirtide
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reconstitute, 45 min into sol, refrigerate after reconstitution, use within 24 hours and do not use cold
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a/e for cisplatin and ways to treat those a/e
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- severe n/v - premedicate with odansetron
- kidney damage - IV hydrate and flush with mannitol |
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nsg int. for cisplatin
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do no use with aluminum needles or IV sets
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what kind of drug is enfuvirtide
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fusion inhibitor
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what kind of drug is efavirenz
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NNRTI
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what's good about efavirenz
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penetrates CNS
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a/e for efavirenz
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skin rash, steven johnson, GI, CNS
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d/i for efavirenz
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midazolam, triazolam
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nsg int. for efavirenz
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- dose at bedtime
- avoid high fat meals - contraindicated in preg. |
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what kind of drug is raltegravir
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integrase inhibitor
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clinical use for raltegravir
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for multi-drug resistant infection
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a/e for raltegravir
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GI, mi, renal failure
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precaution for raltegravir
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myopathy, rhabdomyolysis
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what kind of drug is vincristine
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mitotic poison
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a/e of vincristine
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neurologic rxn, vesicant
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which chemo drugs are vesicant
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mechlorethamine, doxorubicin, vincristine
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precaution with route for vincristine
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-intrathecal route can be fatal
-don't mistake it with vinblastine |
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what kind of drug is bleomycin
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antibiotic
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a/e of bleomycin
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-pulmonary toxicity
- anaphylaxis - test dose |
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what kind of drug is doxorubicin
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antibiotic
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a/e of doxorubicin (not precaution)
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cardiomyopathy
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precaution of doxorubicin
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red color urine
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what kind of drug is dipyrimadole
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antiplatelet
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what does dipyrimadole do
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coronary vasodilator with antiplatelet activity
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what kind of drug is mecholorethamine
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alkylating agent
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property of mechloromethamine
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highly unstable, vesicant
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a/e of mechloromethamine
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n/v, BM dpr, malignancies, immunosup,, arrest spermatogenesis
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precaution mecholoromethamine
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extremely toxic, do not inhale vapors, neutralize any reusable equipment and unused sol.
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clinical use of aspirin
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prevent MI, post MI- prevent infarction, TIA - prevent stroke
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what kind of drug is zidovudine
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NRTI
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property of zidovudine
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artificial AZT analog
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dosage of zidovudine
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200mg TID or 300 mg BID
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a/e of zidovudine
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BM dpr, anemia, nausea, severe HA< insomnia, myalgia
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what kind of drug is didanosine
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NRTI
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property of didanosine
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sensitive to acid, so it is given with mag+ hydroxide
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a/e of didanosine
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pain peripheral neuropathy, acute pancreatitis (FDA), GI, weight gain
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FDA warning on didanosine
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acute pancreatitis
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food precaution didanosine
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dont' mix with juices or carbonated drink, take on empty stomach
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d/i didanosine
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ketoconazole
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what kind of drug is metrothrexate
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antimetabolite
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a/e of methotrexate
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ulcerative stomatitis, BM dpr,
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antidote for methotrexate
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leucovorin
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nsg consideration with methotrexate and its antidote
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leucovorin given with methotrexate to kill cancer cells then after 24 hrs rescue BM from toxic effects of methotrexate
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clinical use for pentamidine isethionate
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PCP and african trypanosomyasis
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who would take pentamidine isethionate
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those who can't take septra or if allergic to sulfa drugs
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route selection for pentamidine isethionate
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active inf = IM/IV, prophylaxis = inhalation
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a/e of pentamidine isethionate
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hypotention (due to IJ), blood dyscrasias, hypo and hyperglycemia, pancreatitis
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nsg int for pentamidine isethionate
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give IJ while lying down to prevent hypotension
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what kind of drug is lamivudine
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NRTI
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alternate use of lamivudine
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chronic hepatitis B
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a/e lamivudine
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gi, ha, neutropenia, peripheral neuropathy
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nsg int with lamivudine
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usually combined with zidovudine to reduce zdv resistance
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what kind of drug is indinavir
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protease inhibitor
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d/i of indinavir
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midazolam, triazolam
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properties of indinavir
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good oral bioavailability, resistance develops slowly
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a/e of indinavir (not long term complications)
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mild elevated indirect bilirubin, kidney stones (drink 48oz or water qd)
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what are the long term complications of indinavir (not a/e)
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hyperglycemia, hyperlipidemia, lipodystrophy (protease paunch, facial wasting)
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nsg int. for indinavir
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best absorb empty stomach; light carb meal (dry toast with jelly or dry cereal)
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name four things you remember for cyanocobalamin
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- vit b12
- IM inj for pernicous anemia - do not give with folic acid - neurological symptoms (differentiates with folic acid def.) |
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advantages of enoxparin
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- advantage - improved bioavailability of SC dosing, long 1/2 life, outpatient use
- lab monitoring not always needed |
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clinical use of enoxaparin
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prophylaxis DVT
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a/e enoxaparin
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bleeding, thrombocytopenia, ecchymosis, epidural/spinal hematoma
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FDA enoxaparin
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epidural spinal hematoma
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a/e ferrous sulfate
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gi, red/dark stools, acute poisoning
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pt teaching ferrous sulfate
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take after meal, less gi upset
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