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36 Cards in this Set
- Front
- Back
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Has been associated with lower cord pH when given in high doses compared to neo
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Ephedrine
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Ephedrine increases:
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HR, PVR, contractility
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Ephedrine increases PVR mostly in _____ and increases _____
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Capacitance vessels; venous return
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Ephedrine can be given ______ but is recommended _____
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IM; IV
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Ephedrine is used to tx hypotension following:
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Regional anesthesia
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Ephedrine can be used to prevent:
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Hypotension
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Ephedrine is metabolized by:
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Liver and kidneys
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Ephedrine: _____ is excreted unchanged in urine
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40%
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Ephedrine can cause:
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Tachyphylaxis
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Tachyphylaxis is where repeated doses may have a:
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Reduced effect
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If tachyphylaxis develops while using ephedrine, may need to:
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Switch to neo
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Direct acting A1 agonist
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Neo
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Neo causes _____ at high doses
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Uterine artery constriction
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At low doses with neo, ______ is maintained and there is little ______
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HR, CO; uterine constriction
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At high doses with neo, there is _______ with reduction in CO, and ____ can occur
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Reflex brady; uterine constriction
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High doses of neo can cause:
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Maternal and fetal compromise
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Use neo when:
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Tachycardia is undesirable in mom or baby
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Use neo when:
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50 mg ephedrine failed to improve bp
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Use neo when there is:
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Maternal cocaine use
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Dissociative anesthetic:
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Ketamine
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Ketamine is a _____ receptor blocker, cortex/limbic system
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NMDA
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Ketamine produces:
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Sedation, immobility, amnesia, marked analgesia
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Ketamine produces:
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Feeling of dissociation from environment without unconsciousness
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Ketamine produces:
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Hallucinations
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Ketamine produces:
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Effects based on dose dependence
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Ketamine maintains your airway reflexes whereas _____ does not
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Propofol
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Ketamine increases:
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Salivation, phonation, non purposeful movement
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Ketamine increases:
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HR and BP
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Is great for asthmatics d/t sympathomimetic properties
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Ketamine
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Ketamine indirect effect is d/t
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Sympathetic stim (> HR and BP)
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Ketamine direct effect is:
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Myocardial depression
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Ketamine should be ____ or used carefully in ____ pt's as there can be dramatic increases in BP with induction and intubation
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Avoided; PIH
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_____ effects may predominate with ketamine in situations where SNS is maximally stimulated such as shock or severe hypovolemia
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Direct (myocardial depression)
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Large doses of ______ increase uterine tone
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Ketamine
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Does not reduce uterine blood flow
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Ketamine
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Ketamine rapidly crosses the placenta but does not _____ fetus at 1 mg/kg doses
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Depress
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