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30 Cards in this Set
- Front
- Back
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Prostaglandins alter:
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Myometrial calcium flux
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Prostaglandins release Ca from _____ --> stimulation of ______ --> muscular cx
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SR; actomyocin complex
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3 types of prostaglandins:
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PGE2, PGE1, PGF2a
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Used for cervical ripening
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Prostaglandins
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Used for second trimester abortions
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Prostaglandins
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Used as second line rx for uterine atony
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Prostaglandins
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PGE2 gel:
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Cervical effects predominate
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Used for cervical ripening for labor induction
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PGE2, PGE1
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Used for pregnancy termination:
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PGE2, PGE1
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Misoprostol/cytotec is a
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PGE1
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Misoprostol/cytotec is a
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Synthetic prostaglandin
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Misoprostol/cytotec is a
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Rx for NSAID stomach ulcer
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Misoprostol/cytotec is
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Replacing PGE2
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Cytotec is used with caution in:
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VBAC, IUGR
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______ route of cytotec administration has less risk for hyperstimulation
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Intra-vaginal
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PGF2a: ______ predominates
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Uterine stimulation
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PGF2a used for uterine atony is:
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Hemabate
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Hemabate is kept in the:
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Fridge
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Do not give hemabate:
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IV
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Common s/e of prostaglandins:
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Diarrhea, N/V, cramping, backache, 'feel bad'
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PGE2 s/e:
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Fever, hypotension, reflex tach, tachypnea
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PGF2a if given IV causes:
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Severe HTN, bronchospasm, pulmonary vasoconstriction, tachycardia
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PGF2a contraindications:
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HTN, asthma, allergy
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3 options to give for PP hemorrhage
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Cytotec, hemabate, methergine
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2nd line stimulant given to an asthmatic:
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Methergine
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2nd line stimulant given to a PIH pt:
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Cytotec (least causing of HTN)
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Stop uterine cxs, inhibit PTL, prevent premature delivery
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Tocolytics
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Magnesium is a:
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Smooth muscle relaxant
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Magnesium reduces _____ preventing uterine cxs
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Myometrial calcium levels
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Magnesium has effects on:
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Vascular, bronchial, and uterine tissues
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