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10 Cards in this Set
- Front
- Back
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Natural Penicillins
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G (Na,K,Procaine, benzathine salts)
V (K) |
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Routes of administration of the natural penicillins
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Na and K- SQ, IM, IV
Procaine and benzathine- SQ, IM |
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Pen V formulated for
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oral adm
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procaine is more commonly used than benza because
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benzathine salt has very low conc which may not surpass the MIC of the infecting bacT
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natural pen are active against
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gram + = strept, bacillus, actinomyces, listeria, and erysipelothrix. Not very active against gram - except Pasteurella.
Activity against anaerobes (except Bacteroides fragilis) is moderately good. |
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susc of Staph to natural penicillins
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unpredictable; due to the variable expression of resistance factors in this genus
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indications in SA for use of natural penicillins
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pyometra, oral infections, osteomylitis where mixed presence of aerobic and anaerobic bacteria is common
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natural penicillins - accum in urine
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useful for the tx of UTIs cause by staph, strept, and sometimes even Ecoli
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Horses - use of natural penicillins
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tetanus, and stept throat infection (strangles) by streptococcus equi.
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other uses of natural penicillins to treat...
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mastitis, pneumonia, septic arthritis, and soft tissue and cutaneous infections.
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