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93 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Why use anticoagulants? |
Prevent: clots dvt stroke pe. Tx thrombosis in MI |
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Side effect from anticoagulants |
BLEEDING |
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Ufh moa? |
Binds antithrombin & increases its potency |
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Ufh prophylaxis dose |
5,000 units sc q8 |
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Ufh tx mi dose |
Loading: 80units/kg (once) Infusion: 18 units/kg/hr |
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Heparin antidote |
Protamine sulfate |
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Heparin antidote |
Protamine sulfate |
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Lmwh moa? |
Inhibit Xa |
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Heparin antidote |
Protamine sulfate |
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Lmwh moa? |
Inhibit Xa |
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Warfarin moa? |
Inhibit formation of clotting factors that are Vit K dependent (7/9/10/2) |
SNoT |
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Warfarin antidote |
Vitamin k |
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Warfarin drug inxn |
Amiodarone Levaquin cipro bactrim flagyl diflucan |
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Warfarin drug inxn |
Amiodarone Levaquin cipro bactrim flagyl diflucan |
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Noca's good |
No inr Work fast No food inxn |
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Noca's bad |
No antidote No labs to predict bleeding $$$ |
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Noca's bad |
No antidote No labs to predict bleeding $$$ |
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Pradaxa moa |
Direct thrombin inhibitor Renal fx |
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Noca's bad |
No antidote No labs to predict bleeding $$$ |
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Pradaxa moa |
Direct thrombin inhibitor Renal fx |
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Platelet activation |
Activated when BVs damaged - release thromboxane a2 & adp - form a platelet plug to patch damaged vessel, can sometimes block entire vessel |
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Noca's bad |
No antidote No labs to predict bleeding $$$ |
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Pradaxa moa |
Direct thrombin inhibitor Renal fx |
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Platelet activation |
Activated when BVs damaged - release thromboxane a2 & adp - form a platelet plug to patch damaged vessel, can sometimes block entire vessel |
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Aggrenox components |
Asa 25mg Dipyridamole 200mg |
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Noca's bad |
No antidote No labs to predict bleeding $$$ |
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Pradaxa moa |
Direct thrombin inhibitor Renal fx |
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Platelet activation |
Activated when BVs damaged - release thromboxane a2 & adp - form a platelet plug to patch damaged vessel, can sometimes block entire vessel |
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Aggrenox components |
Asa 25mg Dipyridamole 200mg |
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Brilinta which line of therapy? |
First line antiplatelet |
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Noca's bad |
No antidote No labs to predict bleeding $$$ |
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Pradaxa moa |
Direct thrombin inhibitor Renal fx |
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Platelet activation |
Activated when BVs damaged - release thromboxane a2 & adp - form a platelet plug to patch damaged vessel, can sometimes block entire vessel |
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Aggrenox components |
Asa 25mg Dipyridamole 200mg |
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Brilinta which line of therapy? |
First line antiplatelet |
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Altepace max dose |
Max 90mg 0.9mg/kg IV. |
10% given as bolus first minute then rest over 1hr. Give within 4 hours of stroke |
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Noca's bad |
No antidote No labs to predict bleeding $$$ |
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Pradaxa moa |
Direct thrombin inhibitor Renal fx |
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Platelet activation |
Activated when BVs damaged - release thromboxane a2 & adp - form a platelet plug to patch damaged vessel, can sometimes block entire vessel |
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Aggrenox components |
Asa 25mg Dipyridamole 200mg |
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Brilinta which line of therapy? |
First line antiplatelet |
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Altepace max dose |
Max 90mg 0.9mg/kg IV. |
10% given as bolus first minute then rest over 1hr. Give within 4 hours of stroke |
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Fibrinolytic NOT ever used for: |
Prophylaxis Se: bleeding |
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Noca's bad |
No antidote No labs to predict bleeding $$$ |
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Pradaxa moa |
Direct thrombin inhibitor Renal fx |
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Platelet activation |
Activated when BVs damaged - release thromboxane a2 & adp - form a platelet plug to patch damaged vessel, can sometimes block entire vessel |
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Aggrenox components |
Asa 25mg Dipyridamole 200mg |
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Brilinta which line of therapy? |
First line antiplatelet |
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Altepace max dose |
Max 90mg 0.9mg/kg IV. |
10% given as bolus first minute then rest over 1hr. Give within 4 hours of stroke |
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Fibrinolytic NOT ever used for: |
Prophylaxis Se: bleeding |
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Rocephin |
Hepatic Iv or im Once daily Cidal 3gen cephalosporin Strep all g- except pseudomonas No atypicals Good for cns infections |
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Beta blockers --> |
Decrease heart rate |
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Beta blockers --> |
Decrease heart rate |
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Jnc8 60+ & no diabetes or ckd |
150/90 |
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Beta blockers --> |
Decrease heart rate |
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Jnc8 60+ & no diabetes or ckd |
150/90 |
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Jnc8 under 60 or diabetes/ckd |
140/90 |
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Drugs for CKD |
Acei arb |
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Drugs for CKD |
Acei arb |
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Drugs for black population |
Thiazides ccb |
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Drugs for non-black |
Thiazides ccb acei arb |
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Drugs for non-black |
Thiazides ccb acei arb |
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Clonidine |
Alpha2 centrally acting receptor agonists Use for ht urgency opioid or nicotine w/d. PO or patch |
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Doxasosin brand name |
Cardura Alpha 1 blocker |
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Doxasosin brand name |
Cardura Alpha 1 blocker |
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Propranolol brand name |
Inderal Beta blocker |
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Doxasosin brand name |
Cardura Alpha 1 blocker |
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Propranolol brand name |
Inderal Beta blocker |
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Avoid in copd/asthma patients |
Non selective a1 b1 b2 |
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Ace inhibitor drug + side effect |
Dry cough Lisinopril -pril |
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Arbs drugs |
Losartan valsartan candesartan No dry cough |
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Arbs drugs |
Losartan valsartan candesartan No dry cough |
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Ccb - diphydropyridines |
Amlodipine Se: peripheral edema |
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Ccb - nonDHP |
Dilitazem (cardizem) Verapamil - constipation |
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Ccb - nonDHP |
Dilitazem (cardizem) Verapamil - constipation |
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Diuretic |
Thiazides Loop K+ sparing Aldosterone antagonist |
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Vasodilator |
(Apresoline) hydralazine |
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Vasodilator for ht emergency |
Sodium nitroprusside |
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Stable angina |
Due to stress or exertion |
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Stable angina |
Due to stress or exertion |
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Nitro SL dosing & 911 |
0.4mg SL q 5 min x 3 doses Pain after first 5 min - call 911 |
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Nitro SL side effect |
Headache |
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Drugs to treat angina |
Nitro Beta blockers Ccb |
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Lipid goals |
Ldl <100 (bad) Hdl m >40 f>50 (good) Tg <150 Total 200 |
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Why treat high cholesterol? |
Risk of CHD higher in pt w high cholesterol |
Diet and exercise don't always work!! |
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Why treat high cholesterol? |
Risk of CHD higher in pt w high cholesterol |
Diet and exercise don't always work!! |
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Statins moa |
Inhibit Hmg-CoA reductase --> lowers cholesterol prod in liver |
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Why treat high cholesterol? |
Risk of CHD higher in pt w high cholesterol |
Diet and exercise don't always work!! |
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Statins moa |
Inhibit Hmg-CoA reductase --> lowers cholesterol prod in liver |
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Statin side effecr |
Rhabdomyolysis |
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Niacin side effect tx |
Give Asa/nsaid 30 min before niacin to prevent flushing |
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Niacin side effect tx |
Give Asa/nsaid 30 min before niacin to prevent flushing |
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Omega 3 fatty acids side effect |
Lovaza Increase ldl |
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