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21 Cards in this Set
- Front
- Back
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A sustained elevation of systolic and/or diastolic b/p above systolic >140 and/or diastolic > 90 can be diagnosed as HTN.
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True
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Antihypertensive drug tx should be given as soon as a pt has SBP at 120-139 or DBP 80-89.
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False
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Obesity is a risk factor for HTN b/c the work load of the CV system in increased. In addition, fat tissue during obesity produces some factors that cause vasoconstriction and enhances renal Na retention, also leading to HTN.
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True
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The antihypertensive action of clonidine is d/t reduction of the sympathetic outflow from vasopressor centers in the brainstem via central alpha-2 receptors.
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True
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In hypertensive crisis, alpha-adrenoceptor antagonists can be used, and they are also frontline drugs for chronic HTN.
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False
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A beta-receptor blocker with partial agonist action (ISA) that also possesses membrane stabilizing effect is propranolol.
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False
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One commonly used vasodilators is hydralazine. It decreases bp b/c it reduces total peripheral resistance.
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True
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In hypertensive pts with chronic heart failure, a type of antihypertensive drug contraindicated is calcium channel blockers.
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True
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What class of drugs is not sympathoplegic?
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Ca channel blockers
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The target of B-adrenoceptor antagonists such as propranolol on the heart is:
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B1-adrenoreceptors
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A B-blocker such as propranolol will not have this adverse effect during tx of HTN:
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Increase in HR
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An antihypertensive agent that will mainly increase intracellular cGMP levels and thereby produce vasodilation and lower bp:
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Hydralazine
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Name a drug that is commonly used to lower bp, but not to decrease HR.
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Nifedipine
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The renal action of ACE inhibitors to increase Na excretion and thereby lower bp is d/t:
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Decrease in aldosterone production
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What is the mechanism that contributes to ACE inhibitor-induced dry cough?
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Decreased degradation of bradykinin
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First choice treatment for a hypertensive pt with chronic heart failure:
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Captopril
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When the use of hydralazine leads to Na retention in pts, what antihypertensive agent should be used in combination to overcome the problem?
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Diuretics
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Which type of antihypertensives should be used in combination to reduce renin?
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ACE inhibitors and B-adrenoreceptor blockers
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Which drug do you give to pts in combination with hydralazine to prevent enhancement of sympathetic activity?
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b-adrenoreceptor blockers
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Which drug do you give to replace captopril when a pt has a dry cough?
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Angiotensin II type I receptor blocker
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Calcium channel blockers are effective in tx of some special groups of pts that are less responsive to other antihypertensive drugs.
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True
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