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163 Cards in this Set
- Front
- Back
Amoxicillin
|
Penicillin
(aminopenicillin) |
|
Erythromycin
|
macrolide
|
|
Azithromycin
|
macrolide
|
|
Milk of magnesia
|
Magnesium containing antacid
|
|
Basaljel
|
aluminum containing antacid
|
|
amphojel
|
aluminum containing antacid
|
|
maalox
|
aluminum containing antacid
calcium containing antacid |
|
mylanta
|
aluminum containing antacid
|
|
tums
|
calcium containing antacid
|
|
Alka-seltzer
|
sodium containing antacid
|
|
lansoprazole
|
proton pump inhibitor
|
|
omeprazole
|
proton pump inhibitor
|
|
pantoprazole
|
proton pump inhibitor
|
|
rabeprazole
|
proton pump inhibitor
|
|
esomeprazole
|
proton pump inhibitor
|
|
proton pump inhibitors end/start with "-"
|
-"prazole"
|
|
H2 Receptor agonists end/start with "-"
|
-"tidine"
|
|
cimetidine
|
H2 Receptor agonists
|
|
famotidine
|
H2 Receptor agonists
|
|
ranitidine
|
H2 Receptor agonists
|
|
nizatidine
|
H2 Receptor agonists
|
|
sulfasalazine
|
immunomodulators
-treats IBS |
|
Ace inhibitors start/end with "-"
|
-"pril"
|
|
Calcium channel blockers start/end with "-"
|
-"dipine"
except for 2 -diltiazem -verapamil |
|
diltiazem
|
calcium channel blocker
|
|
verapamil
|
calcium channel blocker
|
|
clonidine
|
centerally acting alpha2 receptor agonist
|
|
loop diuretics start/end with "-"
|
-"amide" or -"anide"
|
|
hydrochlorothiazide
|
thiazide diuretic
|
|
chlorothiazide
|
thiazide dieretic
|
|
metalozone
|
thiazide like
|
|
chlorthalidone
|
thiazide like
|
|
indapamide
|
thiazide like
|
|
lipid lowering agents start/end with "-"
|
-"statin"
|
|
acyclovir
|
antiviral
|
|
trifluridine
|
antiviral
|
|
amantadine
|
antiviral
|
|
rimantadine
|
antiviral
|
|
zanamivir
|
antiviral
|
|
oseltamivir
|
antiviral
|
|
ribavirin
|
antiviral
|
|
cidofovir
|
antiviral
|
|
foscamet
|
antiviral
|
|
amphotericin B
|
antifungal
|
|
fluconazole
|
antifungal
|
|
voriconazole
|
antifungal
|
|
nystatin
|
antifungal
|
|
terbinafine
|
antifungal
|
|
amiloride
|
potassium sparing diuretic
|
|
spironolactone
|
potassium sparing diuretic
|
|
triamterene
|
potassium sparing diuretic
|
|
metolazone
|
thiazide-like diuretic
|
|
chlorthalidone
|
thiazide-like diuretic
|
|
indapamide
|
thiazide-like diuretic
|
|
dabigatran
|
anticoagulant
|
|
argatroban
|
anticoagulant
|
|
tirofiban
|
antiplatelet
|
|
eptifibatide
|
antiplatelet
|
|
abciximab
|
antiplatelet
|
|
antiplatelets start/end with "-"
|
-usually -"grel" or "grol"
-except for tirofiban, eptifibatide, abciximab, and aspirin |
|
Bile acid Sequestrants start/end with "-"
|
"Cholest-" or "colest"
|
|
cholestyramine
|
bile acid sequestrant
|
|
metaproterenol
|
short acting beta 2 agonist
bronchodilator |
|
Long acting beta agonist inhalers end/start in "-"
|
end in -"meterol" or -"moterol"
|
|
Anticholinergics end/start in "-"
|
-end in -"tropium"
|
|
Theophylline
|
xanthine derivative
|
|
Prednisone
|
glucocortioid (PO)
|
|
dexamethasone
|
glucocorticoid (IV/IM)
|
|
insulin lispro
|
rapid acting
|
|
insulin aspart
|
rapid acting
|
|
insulin glulisine
|
rapid acting
|
|
rapid acting
-onset -peak -duration |
O: 15 minutes
P: 1-2 hours D: 3-5 hours |
|
Humulin R
|
short acting insulin
|
|
Novolin R
|
short acting insulin
|
|
short acting insulin
-onset -peak -duration |
O: 30-60 min
P- 2.5 hours D: 6-10 hours |
|
Insulin Glargine
|
long acting
|
|
Insulin Detemir
|
Long actin
|
|
Long acting insulin onset
|
1-2 hours
|
|
Glimepiride
|
Sulfonylureas
|
|
glyburide
|
sulfonylureas
|
|
glipizide
|
sulfonylureas
|
|
sulfonyureas end/start with "_"
|
-"ride" or -"zide
"Gly-" or "Gli-" |
|
Metformin
|
Biguanide
|
|
Prediabetes dx criteria
-A1C -fasting glucose |
A1C: 5.7 - 6.4%
FG: 100-126 |
|
DM II dx criteria
-A1C -random plasma glucose -fasting plasma glucose -2 hour plasma glucose |
A1C: >6.5%
Random: >200 w/symptoms Fasting: >126 2 Hour: >200 |
|
Penicillin's MOA
|
inhibits cell wall synthesis
|
|
Macrolides MOA
|
inhibits bacterial growth
-bactericidal binds to 50s -inhibits protein synthesis |
|
Cephalosporins MOA
|
-disrupts cell wall
-bactericidal |
|
Tetracycline MOA
|
-inhibits bacterial growth
-binds to 30s -inhibits protein synthesis |
|
Sulfa Drugs MOA
|
-inhibits folic acid synthesis
-inhibits growth |
|
Aminoglycosides MOA
|
-binds to 30s bacterial ribosomes
-inhibits protein synthesis -suppresses bacterial growth |
|
Antifungals MOA
|
-disrupts fungal membranes
|
|
Vancomycin MOA
|
-inhibits cell wall synthesis
-lyses and death of cell |
|
Drug of choice for MRSA and staph?
|
Vancomycin
|
|
Clindamycin MOA
|
-broad spectrum
-inhibits protein synthesis -bactericidal |
|
Linezolid MOA
|
-binds to 23s ribosomes
-inhibits protein synthesis -inhibits growth |
|
Metronidazole MOA
|
-kills bacterial cell by breaking DNA strand
-works against anaerobes |
|
Antivirals MOA
|
-blocks polymerase enzyme
-suppresses synthesis of new viral genome -results in impaired viral replication |
|
Ferrous Sulfate MOA
|
-O2 carrier in Hgb and myoglobin
-corrects IDA |
|
Antacids MAO
|
-neutralizes stomach acid
-does not prevent acid overproduction -reduces symptoms of heartburn |
|
Proton Pump Inhibitors MOA
|
-blocks the proton pump
-prevents H+ ions from moving out of parietal cells -blocks all gastric acid secretion |
|
H2 Receptor Antagonists MOA
|
-block the h2 receptor of acid producing parietal cells
-reduces but does not completely abolish acid secretion |
|
Ace Inhibitors MOA
|
-inhibits ACE
-conversts AT1 to AT2 -prevents breakdown of bradykinin -reduces afterload and vasodilation -reduces BP |
|
what is the drug of choice for diabetic pts with HTN
|
ace inhibitors
|
|
Beta Blocker MOA
|
-block Beta 1 receptors
-reduces heart rate -reduces secretion of renin which reduces secretion of AT2 -results in lower BP |
|
Calcium Channel Blockers MOA
|
-block binding of calcium to its receptor
-prevents muscle ontraction and promotes smooth muscle relaxation -reduces systemic vascular resistance -lowers BP |
|
Centrally Acting Alpha2 Receptor Agonists MOA
|
-stimulates alpha2-adrenergic receptors in the brain
-decreases sympathetic outflow from the CNS -Decreases norepinephrine production -reduces renin activity in the kidneys -lowers BP |
|
Digoxin MOA:
|
-increase myocardial contractility
-changes electrical conduction properties of the heart -decreases rate of electrical conduction -prolongs refractory period b/w SA and AV node |
|
Digoxin Toxicity antidote
|
Potassium
|
|
Loop Diuretics MOA
|
-blocks sodium readsorption in the thick ascending loop of Henle
|
|
Potassium-Sparing Diuretics MOA
|
-Blocks aldosterone action in the kidney
-prevents K+ from being pumped into tubule, thus preventing secretion -competitively blocks aldosterone receptors and inhibits action |
|
Thiazide and thiazide-like diuretics MOA
|
-Inhibits tubular resorption of sodium, chloride, and potassium
-works primarily in distal convoluted tubule -excretes water, sodium, and chloride -results in lowered peripheral vascular resistance |
|
HMG-CoA reductase inhibitor MOA
|
-most potent LDL reducer
-inhibits Hmg-CoA reductase which is used by liver to produce cholesterol |
|
what is the first line drug therapy for hypercholesterolemia?
|
-Hmg-CoA reductase inhibitors
-aka "statins" |
|
Bile acid sequestrants MOA
|
-prevent reabsorption of bile acids form small intestine
-no bile acids = no absorption of cholesterol |
|
Anticoagulants MOA
|
-inhibits the action of formation of clotting factors
-prevents clot formation -works on different areas of the clotting cascade -does not lyse existing clots |
|
Heparin antidote
|
-protamine sulfate
|
|
what do we monitor with warfarin?
|
prothrombin time and INR
|
|
desired therapeutic INR level with warfarin?
|
-2 - 3.5 INR
|
|
Warfarin antidote
|
vitamin K
|
|
Antiplatelets MOA
|
-inhibit platelet aggregation
-prevents platelet plugs |
|
Beta 2 agonists MOA
|
-begins at specific receptor stimulated
-dilates airway -activation of beta 2 receptors stimulates cAMP -relaxes smooth muscle in airways |
|
Anticholinergics MOA
|
-Ach causes ronchial constriction and narrowing of airways
-binds to Ach receptors -prevents bronchoconstriction and airways dilate |
|
Theophylline MOA
|
-increases levels of energy producing cAMP
-competitively inhibits phosphodiesterase (enzyme that breaks down cAMP) -results in smooth muscle relaxations, bronchodilations, and increased air flow |
|
Cromolyn
|
Mast cell Stabilizer
|
|
Sulfonyureas MOA
|
-stimulates insulin secretion from beta cells of pancreas
-beta cell function must be present -decrease liver glycogenolysis and gluconeogenesis -increases cellular sensitivity to insulin |
|
Biguanide MOA
|
-decreases production of glucose by liver
-decrease intestine absorption of glucose -improve insulin sensitivity in tissues -does not affect beta cells or increase insulin production |
|
alternate drug class for pts allergic to PCNs
|
macrolides
|
|
What med class treats serious/life-threatening infections caused by E. Coli, K. Pneumoniae, P. Mirabilis, P. Aeruginosa?
|
aminoglycosides
|
|
Vancomycin indications
|
-severe infections only
-MRSA & staph -antibiotic induced Pseudomembranous colitis |
|
Metronidazole indications
|
-infection of abdominal organs (pseudomembranous colitis)
-PUD caused by H. pylori -Helminthic infection |
|
Proton Pump Inhibitors indications
|
-GERD
-PUD -zollinger-ellison syndrome |
|
H2 receptor antagonist indications
|
-GERD
-PUD -GI disorders |
|
ACE inhibitors indications
|
-CHF
-HTN |
|
Beta Blockers indications:
|
-HTN
-angina -MI -tremor |
|
Calcium Channel Blockers indications
|
-angina
-HTN -dysrhythmias |
|
Digoxin indications:
|
-HF
-atrial fibrillation -supraventricular dysrhythmias |
|
Loop diuretics Indications
|
-HTN
-Hypercalcemia -CHF -Fluid overload |
|
Potassium sparing diuretics indications
|
-HTN
-reversing K+ loss -CHF |
|
Thiazide and thiazide-like diuretic indications
|
-Edema
-HTN -CHF -Ascites r/t HF |
|
Hmg-CoA reductase inhibitor indications
|
-hypercholesterolemia
-hyperlipidemia |
|
Anticoagulant indications
|
-clot formation prevention
-MI -unstable angina -atrial fibrillation |
|
antiplatelets indication:
|
-reduces risk of fatal and nonfatal strokes
-acute unstable angina -MI |
|
Beta 2 Agonist indication
|
-bronchospasm r/t asthma and bronchitis
-treats and prevents asthma attacks |
|
anticholinergics indications
|
-COPD and emphysema
|
|
Theophylline indication
|
-asthma
-chronic bronchitis -emphysema -mild-mod acute asthma attacks -COPD maintainance |
|
Sulfonylureas indications
|
-DM II w/ working pancreas
|
|
Biguanide indication
|
-newly diagnosed DM II
|
|
aminoglycosides end/start with "-"
|
"-acin", "-icin", or "-mycin"
-dont confuse with macrolides |
|
Quinolones end/start with "-"
|
"-floxacin"
|
|
Sulfonamides end/start with "-"
|
"sulfa-"
|
|
Cephalosporins end/start with "-"
|
"ceph-", "cef-"
or "-cef" |
|
Amoxicillin
|
aminoPCN
|
|
ampicillin
|
aminoPCN
|
|
aminopenicillins:
|
ampicillin and amoxicillin
|
|
Macrolides end/start with "-"
|
"-mycin"
dont confuse with aminoglycosides |
|
tetracyclines end/start with "-"
|
"-cycline"
|
|
Alpha 1 blockers end/start with "-"
|
"-zosin"
|
|
Carvedilol
|
duel A1 and B Blocker
|
|
Labetalol
|
dues A1 and B blocker
|
|
2 duel A1 and B blockers
|
"carved and labeled"
-carvedilol -labetalol |
|
ARBS end/start with "-"
|
"-sartan"
|
|
Anticoagulants end/start with "-"
|
most have "-arin" at end or in middle
-except for dabigatran and argatroban |