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25 Cards in this Set
- Front
- Back
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Phenylbutazone
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analgesic, anti-inflammatory. used for arthritis and gout. easily displaced from albumin. inhibits P450
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Tolbutamide
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Type 2 diabetes.
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Phenytoin
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antileptic; used for epilepsy and other seizure disorders. induces P450
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Methadone
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analgesic and tx for heroin addiction
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What drugs cause bone marrow toxicity?
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Chem agents, chloramphenicol, ganciclovir, zidovudine, interferon, flucytosine, carbamazepine
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Which drugs cause hepatotoxicity?
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All imidazoles, interferon, nevirapine, all HMG CoA inhibitors, valproic acid, isoniazid
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Which drugs cause nephrotoxicity?
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AGS, foscarnet, cidofovir, NSAIDs, cyclosporine, amphotericin
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Tendon ruptures?
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Quinolones
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DVTS?
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raloxifene, tamoxifen, esrogens/progesterones
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Orthostatic hypotension
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All alpha blockers, most TCAs
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Hypertensive Crisis
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MAO inhibitors, TCA
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Serotonin syndrome
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MAO inhibitors, SSRIs, Decongestants that contain pseudoephedrine, TCAs, SNRIs
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Cutaneous flushing
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niacin
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Seizure SE
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meperidine
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Drug induced Lupus
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hydralazine, procainamide
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Malignant hypothermia
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halothane
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NAION
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PDE-5 inhibitors
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Ototoxicity
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AGs, PDE-5 inhibitors
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Neural tube defects
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carbamazepine, valproic acid
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Ebsteins anomaly
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lithium
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What is interferon used for?
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tx chronix hepatitis B or C or to tx multiple sclerosis. Can cause hepatotoxicity
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Phenacetin
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formerly used as an analgesic and antipyretic was able to cause severe nephrotoxicity
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Meperidine
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opioid analgesic. may cause serotonin syndrome if combined with MAO inhibitors
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Bupropion
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antidepressant and smoking cessation
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procainamide
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cardiac depressant used to tx supraventricular and ventricular arrhythmias. may cause drug induced lupus
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