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109 Cards in this Set

  • Front
  • Back
Prevent the synthesis of angiotensin II, a potent vasoconstrictor; used to treat hypertension, heart failure and kidney disease
ACE inhibitors
Promote the accumulation of acetylcholine, resulting in prolonged cholinergic effects
acetylcholinesterase inhibitors
Produce effects similar to the neurotransmitter norepinephrine
adrenergic
Inhibits the adrenergic system, preventing stimulation of the adrenergic receptors
adrenergic blocking agents
Block stimulation of mineralocorticoid receptors by aldosterone, thus reducing high blood pressure by preventing sodium reabsorption
aldosterone receptor antagonists
Gentamicin, tobramycin, and related antibiotics; particularly effective against gram-negative microorganisms; noted for potentially dangerous toxicity
aminoglycosides
Used to reduce elevated postprandial hyperglycemia (pramlintide) in patients with type 1 or type 2 diabetes mellitus
amylinomimetic agent
Narcotic and nonnarcotic; relieve pain without producing loss of consciousness or reflex activity
analgesics
These steroid hormones produce maculinizing effects
androgens
For example: local anesthesia, general anesthesia; cause a loss of sensation with or without a loss of consciousness
anesthetics
also known as ARB's (angiotensin receptor blockers); act by binding to angiotensin II receptor sites, preventing angiotensin II from binding to receptor sites in vascular smooth muscle, brain, heart, kidneys, and adrenal gland; thus, blocking the blood pressure-elevating and sodium-retaining effects of angiotensin II
angiotensin II receptor antagonists
Reduce the aciditiy of the gastric contents
antacids
Used to prevent or treat attacks of angina pectoris; most common in nitroglycerin
antianginals
Used to treat anxiety symptoms or disorders; AKA minor tranquilizers or anxiolytics
antianxiety
Used to treat infections caused by pathogenic microbes; the term is often used interchangeably with antimicrobial agents
antibiotics
Block the actions of acetylcholine in the parasympathetic nervous system
anticholinergics
Do NOT dissolve existing blood clots, but do prevent formation, enlargement, or extension of blood clots
anticoagulants
Suppress abnormal neuronal activity in the CNS, preventing seizures
anticonvulsants
Relieves depression
antidepressants
Include insulin and amylinomimetic agent used to treat type 1 diabetes mellitus. Secretogogues, biguanide, thiazolidinediones, alpha-glucosidase inhibitors, amylinomimetic agent, and incretin-based therapy are used in the treatment of type 2 diabetes mellitus
antidiabetics
Relieve or control the symptoms of acute or chronic diarrhea
antidiarrheals
Used to correct cardiac dysrhythmias
antidysrhythmics
Used to prevent or treat nausea and vomiting
antiemetics
Used to treat fungal infections
antifungals
Used to reduce intraocular pressure
antiglaucoma
Used to treat active gout attacks or to prevent future attacks
antigout
Used to treat allergy symptoms; may also be used to treat motion sickness, insomnia and other nonallergic reactions
antihistamines
Used to treat elevated blood pressure
antihypertensives
Used to reduce serum cholesterol and/or triglycerides; most common are statins
antilipemics
Chemicals that eliminate living microorganisms pathogenic to the patient; also called antibiotics or antiinfectives
antimicrobials
Also called chemotherapy agents; used alone or in combination with other treatment modalities such as radiation, surgery,or biologic response modifiers to treat cancer
antineoplastics
Used in the treatment of Parkinson's syndrome and other dyskinesias
antiparkinson's
Prevent platelet clumping (aggregation), thereby preventing an essential step in formation of a blood clot; most common are asprin and clopidogrel
antiplatelets
Used to treat severe mental illnesses
antipsychotics
Used to reduce fevers associated with a variety of conditions; most common are aspirin, acetaminophen, and ibuprofen
antipyretics
Actually anticholinergic agents
antispasmodics
Used to treat the symptoms of hyperthyroidism; AKA thyroid hormone antagonists
antithyroid
Used to prevent or treat an infectioncaused by 'Mycobacterium tuberculosis'
antituberculins
Used to suppress a cough by acting on the cough center of the brain
antitussive
These drugs, such as histamine (H2) antagonists, decrease the volume and increase the pH of gastric secretions
antiulcer agents
Used to treat infections caused by pathogenic viruses
antivirals
Inhibit the activity of the sympathetic transmitters, norepinephrine, and epinephrine; used to treat angina, dysrythmias, hypertension, and glaucoma
beta blockers
Stimulate receptors within the tracheobronchial tree to relax and dilate the airway passages, allowing a greater volume of air to be exchanged and improving oxygenation
bronchodilators
Also called calcium ion antagonists, slow channel blockers, or calcium ion influx inhibitors; inhibit the movement of calcium ions across the cell membrane; used to decrease dysrythmias, slow rate of contraction of the heart, and cause vasodilation
calcium channel blockers
Antibiotics with a broad spectrum of activity against gram-positive and gram-negative bacteria; they act by inhibiting cell wall synthesis
carbapenems
Interfere with the production of aqueous humor, thereby reducing intraocular pressure associated with glaucoma
carbonic anhydrase inhibitors
Improve immune function by stimulating the activity of various immune cells
cell-stimulating agents
Also known as parasympathomimetics; produce effects similar to those of acetylcholine
cholinergic
Cholinesterase enzymes destroy acetylcholine, stopping its actions. These block destructions of acetylcholine, thus prolonging its action.
cholinesterase inhibitors
This drug, sucralfate, forms a complex that adheres to the crater of an ulcer, protecting it from aggravation from gastric secretions
coating agent
Stimulate progenitor cells in bone marrow to increase numbers of leukocytes, thereby improving immune function
colony-stimulating factors
These hormones are secreted by the adrenal cortex of the adrenal gland
corticosteroids
Anticholinergic agents that paralyze accomodation of the iris of the eye
cycloplegics
Agents that cause direct cell deathl often used for cancer chemotherapy
cytotoxics
Reduce swelling in the nasal passages caused by a common cold or allergic rhinitis, usually by vasoconstriction
decongestants
Combination products containing digestive enzymes used to treat various digestive disorders and to supplement deficiencies of natural digestive enzymes
digestants
A class of drugs, also known as cardiac glycosides, that increase the force of contraction and slow the heart rate, thereby improving cardiac output; digoxin is the prototype
digitalis glycosides
Act to increase the flow of urine
diuretics
Used to induce vomiting
emetics
Steroids that cause feminizing effects
estrogens
Liquify mucus by stimulating the natural lubricant fluids from the bronchial glands, allowing the liquified mucus to be expectorated or coughed up out of the trachea and bronchi
expectorants
Ciprofloxacin and related agents; widely used broad-spectrum antibiotics
flouroquinolones
Used to increase stomach contractions, relax the pyloric valve, and increase peristalsis in the gastrointestinal tract; results in a decrease in gastric transit time and more rapid emptying of the intestinal tract; prototype is metoclopramide
gastric stimulants
AKA adrenocorticosteroids; are used to regulate carbohydrate, fat, and protein metabolism
glucocorticoids
Hormones produced by the testes in the male and ovaries in the female
gonadal hormones
Plant products usually sold as food supplements; may have pharmacologic effects that are not evaluated or regulated by the FDA
herbals
Decrease the volume and increase the pH of gastric secretions both during the day and the night
histamine (H2) antagonists
AKA the statins; antilipemic agents that inhibit hydroxymethyl-glutaryl coenzyme A reductase enzyme, the enzyme that stimulates the conversion of HMG-CoA to mevalonic acid, a precursor in the biosynthesis of cholesterol, thus reducing the potential for artherosclerosis
HMG-CoA reductase enzyme inhibitors
Used to decrease the production or increase the excretion of uric acid excretion of uric acid, thus lowering serum uric acid levels to prevent gout
hyperuricemics
Used to produce sleep
hypnotics
Used to reduce basal glucose concentrations and elevated postprandial glucose concentrations; used to treat diabetes mellitus
incretin-mimetics
Hormone required for glucose transport into the cells for energy
insulins
Used to prevent psysiologic lactation
lactation suppressants
Act by a variety of mechanisms to treat constipation
laxatives
Derivatives of heparin; anticoagulants for prophylactic treatment of pulmonary thromboembolism and deep vein thrombosis
low molecular weight heparins
Erythromycin, azithromycin, and related antibiotics
macrolides
Agents that block monoamine oxidase, thereby preventing the degradation and prolonging the action of norepinephrine and serotonin
MAO inhibitors
Steroids that cause the kidneys to retain sodium and water
mineralocorticoids
Cause constriction of the iris
miotics
reduce the thickness and stickiness of pulmonary secretions by acting directly on the mucous plugs to dissolve them
mucolytics
Relieve muscle spasms
muscle relaxants
Cause dilation of the iris
mydriatics
Aprepitant is the first neurokinin-1 available; blocks the effects of substance P on the neurokinin-1 receptors. Used to prevent acute and delayed chemotherapy-related nausea and vomiting caused by highly emetogenic antineoplastic agents
neuro-kinin-1 receptor antagonist
Skeletal muscle relaxants used to produce muscle relaxation during anesthesia; reduce the use and side effects of general anestheticsl used to ease endotracheal intubation and prevent laryngospasm
neuromuscular blockers
Metabolize to nitric oxide, a potent vasodilator used to treat angina
nitrates
Prostaglandin inhibitors that are analgesic, antipyretic, and anti-inflammatory in action
nonsteroidal antiinflammatory drugs (NSAIDs)
Centrally acting analgesic agents related to morphine
opioids
Used for birth control; administered orally
oral contraception
Used in type 2 diabetes mellitus to improve glucose metabolism and lower blood glucose levels
oral hypoglycemics
Steroids regulating endometrial and myometiral function used alone or in combination with estrogen for oral contraception
progestins
Saquinavir, ritonavir, indinavir, and related drugs; block the maturation of human immunodeficiency virus; used to treat HIV infections
protease inhibitors
Group of related chemicals that are a subclass of NSAIDs effective as analgesics, antipyretics, and antiinflammatory agents
salicylates
Given to an individual to produce relaxation and rest; do not necessarily produce sleep
sedatives
Antidepressants that act by specifically blocking the reuptake or serotonin, thus prolonging its action
selective serotonin reuptake inhibitors (SSRIs)
Used to block serotonin; prevent emesis induced by chemotherapy, radiation therapy, and surgery
serotonin antagonists
Block the synthesis of cholesterol
statins (HMG-CoA reductase nihibitors)
Draw water into the stool, thereby softening it
stool softeners or fecal softeners
Interfere with the storage and release of norepinephrine and epinephrine
sympathomimetics
A specific group of drugs given to dissolve existing blood clots
thrombolytics
Used to counteract or block the action of excessive formation of thyroid hormones
thyroid hormone antagonists
Used when thyroid hormones are not being produced or are not produced in sufficient quantities to meet the body's physiologic need
thyroid hormones
Inhibit the reuptake of norepinephrine and serotonin
tricyclic antidepressants
Act on the tubules of the kidneys to enhance the excretion of uric acid
uricosuric agents
Produce a local anesthetic effect on the mucosaof the ureters and bladder to relieve burning, pain, urgency, and frequency associated with UTI's
urinary analgesics
Substances excreted and concentrated in the urine in sufficient amounts to have an antiseptic effect on the urine and the urinary tract
urinary antimicrobials
Used primarily to prevent preterm labor and delivery; includes terbutaline
uterine relaxants
Increase the frequency or strength of uterine contractions; includes oxytocin
uterine stimulants
Suspensions of either live, attenuated, or killed bacteria or viruses administered to induce immunity against infection of specific bacteria or viruses
vaccines
Relax the arteriolar amooth muscle causing a dilation of the blood vessels
vasodilators