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109 Cards in this Set
- Front
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Prevent the synthesis of angiotensin II, a potent vasoconstrictor; used to treat hypertension, heart failure and kidney disease
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ACE inhibitors
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Promote the accumulation of acetylcholine, resulting in prolonged cholinergic effects
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acetylcholinesterase inhibitors
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Produce effects similar to the neurotransmitter norepinephrine
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adrenergic
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Inhibits the adrenergic system, preventing stimulation of the adrenergic receptors
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adrenergic blocking agents
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Block stimulation of mineralocorticoid receptors by aldosterone, thus reducing high blood pressure by preventing sodium reabsorption
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aldosterone receptor antagonists
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Gentamicin, tobramycin, and related antibiotics; particularly effective against gram-negative microorganisms; noted for potentially dangerous toxicity
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aminoglycosides
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Used to reduce elevated postprandial hyperglycemia (pramlintide) in patients with type 1 or type 2 diabetes mellitus
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amylinomimetic agent
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Narcotic and nonnarcotic; relieve pain without producing loss of consciousness or reflex activity
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analgesics
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These steroid hormones produce maculinizing effects
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androgens
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For example: local anesthesia, general anesthesia; cause a loss of sensation with or without a loss of consciousness
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anesthetics
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also known as ARB's (angiotensin receptor blockers); act by binding to angiotensin II receptor sites, preventing angiotensin II from binding to receptor sites in vascular smooth muscle, brain, heart, kidneys, and adrenal gland; thus, blocking the blood pressure-elevating and sodium-retaining effects of angiotensin II
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angiotensin II receptor antagonists
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Reduce the aciditiy of the gastric contents
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antacids
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Used to prevent or treat attacks of angina pectoris; most common in nitroglycerin
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antianginals
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Used to treat anxiety symptoms or disorders; AKA minor tranquilizers or anxiolytics
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antianxiety
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Used to treat infections caused by pathogenic microbes; the term is often used interchangeably with antimicrobial agents
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antibiotics
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Block the actions of acetylcholine in the parasympathetic nervous system
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anticholinergics
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Do NOT dissolve existing blood clots, but do prevent formation, enlargement, or extension of blood clots
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anticoagulants
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Suppress abnormal neuronal activity in the CNS, preventing seizures
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anticonvulsants
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Relieves depression
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antidepressants
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Include insulin and amylinomimetic agent used to treat type 1 diabetes mellitus. Secretogogues, biguanide, thiazolidinediones, alpha-glucosidase inhibitors, amylinomimetic agent, and incretin-based therapy are used in the treatment of type 2 diabetes mellitus
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antidiabetics
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Relieve or control the symptoms of acute or chronic diarrhea
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antidiarrheals
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Used to correct cardiac dysrhythmias
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antidysrhythmics
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Used to prevent or treat nausea and vomiting
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antiemetics
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Used to treat fungal infections
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antifungals
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Used to reduce intraocular pressure
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antiglaucoma
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Used to treat active gout attacks or to prevent future attacks
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antigout
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Used to treat allergy symptoms; may also be used to treat motion sickness, insomnia and other nonallergic reactions
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antihistamines
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Used to treat elevated blood pressure
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antihypertensives
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Used to reduce serum cholesterol and/or triglycerides; most common are statins
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antilipemics
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Chemicals that eliminate living microorganisms pathogenic to the patient; also called antibiotics or antiinfectives
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antimicrobials
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Also called chemotherapy agents; used alone or in combination with other treatment modalities such as radiation, surgery,or biologic response modifiers to treat cancer
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antineoplastics
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Used in the treatment of Parkinson's syndrome and other dyskinesias
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antiparkinson's
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Prevent platelet clumping (aggregation), thereby preventing an essential step in formation of a blood clot; most common are asprin and clopidogrel
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antiplatelets
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Used to treat severe mental illnesses
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antipsychotics
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Used to reduce fevers associated with a variety of conditions; most common are aspirin, acetaminophen, and ibuprofen
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antipyretics
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Actually anticholinergic agents
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antispasmodics
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Used to treat the symptoms of hyperthyroidism; AKA thyroid hormone antagonists
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antithyroid
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Used to prevent or treat an infectioncaused by 'Mycobacterium tuberculosis'
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antituberculins
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Used to suppress a cough by acting on the cough center of the brain
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antitussive
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These drugs, such as histamine (H2) antagonists, decrease the volume and increase the pH of gastric secretions
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antiulcer agents
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Used to treat infections caused by pathogenic viruses
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antivirals
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Inhibit the activity of the sympathetic transmitters, norepinephrine, and epinephrine; used to treat angina, dysrythmias, hypertension, and glaucoma
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beta blockers
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Stimulate receptors within the tracheobronchial tree to relax and dilate the airway passages, allowing a greater volume of air to be exchanged and improving oxygenation
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bronchodilators
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Also called calcium ion antagonists, slow channel blockers, or calcium ion influx inhibitors; inhibit the movement of calcium ions across the cell membrane; used to decrease dysrythmias, slow rate of contraction of the heart, and cause vasodilation
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calcium channel blockers
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Antibiotics with a broad spectrum of activity against gram-positive and gram-negative bacteria; they act by inhibiting cell wall synthesis
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carbapenems
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Interfere with the production of aqueous humor, thereby reducing intraocular pressure associated with glaucoma
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carbonic anhydrase inhibitors
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Improve immune function by stimulating the activity of various immune cells
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cell-stimulating agents
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Also known as parasympathomimetics; produce effects similar to those of acetylcholine
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cholinergic
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Cholinesterase enzymes destroy acetylcholine, stopping its actions. These block destructions of acetylcholine, thus prolonging its action.
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cholinesterase inhibitors
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This drug, sucralfate, forms a complex that adheres to the crater of an ulcer, protecting it from aggravation from gastric secretions
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coating agent
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Stimulate progenitor cells in bone marrow to increase numbers of leukocytes, thereby improving immune function
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colony-stimulating factors
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These hormones are secreted by the adrenal cortex of the adrenal gland
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corticosteroids
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Anticholinergic agents that paralyze accomodation of the iris of the eye
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cycloplegics
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Agents that cause direct cell deathl often used for cancer chemotherapy
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cytotoxics
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Reduce swelling in the nasal passages caused by a common cold or allergic rhinitis, usually by vasoconstriction
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decongestants
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Combination products containing digestive enzymes used to treat various digestive disorders and to supplement deficiencies of natural digestive enzymes
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digestants
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A class of drugs, also known as cardiac glycosides, that increase the force of contraction and slow the heart rate, thereby improving cardiac output; digoxin is the prototype
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digitalis glycosides
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Act to increase the flow of urine
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diuretics
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Used to induce vomiting
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emetics
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Steroids that cause feminizing effects
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estrogens
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Liquify mucus by stimulating the natural lubricant fluids from the bronchial glands, allowing the liquified mucus to be expectorated or coughed up out of the trachea and bronchi
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expectorants
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Ciprofloxacin and related agents; widely used broad-spectrum antibiotics
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flouroquinolones
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Used to increase stomach contractions, relax the pyloric valve, and increase peristalsis in the gastrointestinal tract; results in a decrease in gastric transit time and more rapid emptying of the intestinal tract; prototype is metoclopramide
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gastric stimulants
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AKA adrenocorticosteroids; are used to regulate carbohydrate, fat, and protein metabolism
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glucocorticoids
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Hormones produced by the testes in the male and ovaries in the female
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gonadal hormones
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Plant products usually sold as food supplements; may have pharmacologic effects that are not evaluated or regulated by the FDA
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herbals
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Decrease the volume and increase the pH of gastric secretions both during the day and the night
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histamine (H2) antagonists
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AKA the statins; antilipemic agents that inhibit hydroxymethyl-glutaryl coenzyme A reductase enzyme, the enzyme that stimulates the conversion of HMG-CoA to mevalonic acid, a precursor in the biosynthesis of cholesterol, thus reducing the potential for artherosclerosis
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HMG-CoA reductase enzyme inhibitors
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Used to decrease the production or increase the excretion of uric acid excretion of uric acid, thus lowering serum uric acid levels to prevent gout
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hyperuricemics
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Used to produce sleep
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hypnotics
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Used to reduce basal glucose concentrations and elevated postprandial glucose concentrations; used to treat diabetes mellitus
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incretin-mimetics
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Hormone required for glucose transport into the cells for energy
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insulins
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Used to prevent psysiologic lactation
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lactation suppressants
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Act by a variety of mechanisms to treat constipation
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laxatives
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Derivatives of heparin; anticoagulants for prophylactic treatment of pulmonary thromboembolism and deep vein thrombosis
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low molecular weight heparins
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Erythromycin, azithromycin, and related antibiotics
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macrolides
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Agents that block monoamine oxidase, thereby preventing the degradation and prolonging the action of norepinephrine and serotonin
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MAO inhibitors
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Steroids that cause the kidneys to retain sodium and water
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mineralocorticoids
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Cause constriction of the iris
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miotics
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reduce the thickness and stickiness of pulmonary secretions by acting directly on the mucous plugs to dissolve them
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mucolytics
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Relieve muscle spasms
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muscle relaxants
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Cause dilation of the iris
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mydriatics
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Aprepitant is the first neurokinin-1 available; blocks the effects of substance P on the neurokinin-1 receptors. Used to prevent acute and delayed chemotherapy-related nausea and vomiting caused by highly emetogenic antineoplastic agents
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neuro-kinin-1 receptor antagonist
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Skeletal muscle relaxants used to produce muscle relaxation during anesthesia; reduce the use and side effects of general anestheticsl used to ease endotracheal intubation and prevent laryngospasm
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neuromuscular blockers
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Metabolize to nitric oxide, a potent vasodilator used to treat angina
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nitrates
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Prostaglandin inhibitors that are analgesic, antipyretic, and anti-inflammatory in action
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nonsteroidal antiinflammatory drugs (NSAIDs)
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Centrally acting analgesic agents related to morphine
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opioids
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Used for birth control; administered orally
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oral contraception
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Used in type 2 diabetes mellitus to improve glucose metabolism and lower blood glucose levels
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oral hypoglycemics
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Steroids regulating endometrial and myometiral function used alone or in combination with estrogen for oral contraception
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progestins
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Saquinavir, ritonavir, indinavir, and related drugs; block the maturation of human immunodeficiency virus; used to treat HIV infections
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protease inhibitors
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Group of related chemicals that are a subclass of NSAIDs effective as analgesics, antipyretics, and antiinflammatory agents
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salicylates
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Given to an individual to produce relaxation and rest; do not necessarily produce sleep
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sedatives
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Antidepressants that act by specifically blocking the reuptake or serotonin, thus prolonging its action
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selective serotonin reuptake inhibitors (SSRIs)
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Used to block serotonin; prevent emesis induced by chemotherapy, radiation therapy, and surgery
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serotonin antagonists
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Block the synthesis of cholesterol
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statins (HMG-CoA reductase nihibitors)
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Draw water into the stool, thereby softening it
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stool softeners or fecal softeners
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Interfere with the storage and release of norepinephrine and epinephrine
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sympathomimetics
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A specific group of drugs given to dissolve existing blood clots
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thrombolytics
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Used to counteract or block the action of excessive formation of thyroid hormones
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thyroid hormone antagonists
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Used when thyroid hormones are not being produced or are not produced in sufficient quantities to meet the body's physiologic need
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thyroid hormones
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Inhibit the reuptake of norepinephrine and serotonin
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tricyclic antidepressants
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Act on the tubules of the kidneys to enhance the excretion of uric acid
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uricosuric agents
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Produce a local anesthetic effect on the mucosaof the ureters and bladder to relieve burning, pain, urgency, and frequency associated with UTI's
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urinary analgesics
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Substances excreted and concentrated in the urine in sufficient amounts to have an antiseptic effect on the urine and the urinary tract
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urinary antimicrobials
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Used primarily to prevent preterm labor and delivery; includes terbutaline
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uterine relaxants
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Increase the frequency or strength of uterine contractions; includes oxytocin
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uterine stimulants
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Suspensions of either live, attenuated, or killed bacteria or viruses administered to induce immunity against infection of specific bacteria or viruses
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vaccines
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Relax the arteriolar amooth muscle causing a dilation of the blood vessels
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vasodilators
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