Pharm Dr. Kruggers Antimicrobials

Front 1

MOA of quinolones

Back 1

Inhibit DNA gyrase

Front 2

MOA of penicillin

Back 2

Block cell wall synthesis by inhibiting peptidoglycan cross-linkage

Front 3

Drug used for MRSA

Back 3

Vancomycin

Front 4

Vancomycin MOA

Back 4

Blocks peptidoglycan synthesis

Front 5

Type of resistance found with vancomycin

Back 5

Point mutation

Front 6

Meningitis prophylaxis in exposed patients

Back 6

Rifampin

Front 7

Technique used to diagnose perianal itching, and the drug used to treat it

Back 7

Scotch tape technique
and mebendazole

Front 8

Two toxicities of aminoglycosides

Back 8

nephro and ototoxicity

Front 9

DOC for Legionnaires' disease

Back 9

Erythromycin

Front 10

MOA of sulfonamides

Back 10

Inhibit dihydropteroate synthase

Front 11

Penicillins active against penicillinase secreting bacteria

Back 11

Methicillin, nafcillin, and dicloxacillin

Front 12

Cheap wide spectrum antibiotic DOC of otitis media

Back 12

Amoxicillin

Front 13

Class of antibiotics that have 10% cross sensitivity with penicillins

Back 13

Cephalosporins

Front 14

PCN active against pseudomonas

Back 14

Carbenicillin, piperacillin and ticarcillin

Front 15

Antibiotic causing red-man syndrome, and prevention

Back 15

Vancomycin, infusion
at a slow rate and antihistamines

Front 16

Drug causes teeth discoloration

Back 16

Tetracycline

Front 17

MOA of tetracycline

Back 17

Decreases protein synthesis by inhibiting 30S ribosome

Front 18

Drug that causes gray baby syndrome and aplastic anemia

Back 18

Chloramphenicol

Front 19

Drug notorious for causing pseudomembranous colitis

Back 19

Clindamycin

Front 20

DOC for tx of pseudomembranous colitis

Back 20

Metronidazole

Front 21

Treatment of resistant pseudomembranous colitis

Back 21

ORAL vancomycin

Front 22

Anemia caused by trimethoprim

Back 22

Megaloblastic anemia

Front 23

Reason fluoroquinolones are contraindicated in children and pregnancy

Back 23

Cartilage damage

Front 24

DOC for giardia, bacterial vaginosis, pseudomembranous colitis, and trichomonas

Back 24

Metronidazole

Front 25

Treatment for TB patients (think RIPE)

Back 25

Rifampin, Isoniazid, Pyrazinamide, and Ethambutol

Front 26

Metronidazole SE if given with alcohol

Back 26

Disulfiram-like reaction

Front 27

Common side effect of Rifampin

Back 27

Red urine discoloration

Front 28

MOA of nystatin

Back 28

Bind ergosterol in fungal cell membrane

Front 29

Neurotoxicity with isoniazid (INH) prevented by

Back 29

Administration of Vit. B6 (pyridoxine)

Front 30

Toxicity of amphotericin

Back 30

Nephrotoxicity

Front 31

SE seen only in men with administration of ketoconazole

Back 31

Gynecomastia

Front 32

Topical DOC in impetigo

Back 32

Topical mupirocin (Bactroban)

Front 33

DOC for influenza A

Back 33

Amantadine

Front 34

DOC for RSV

Back 34

Ribavirin

Front 35

DOC for CMV retinitis

Back 35

Ganciclovir

Front 36

SE for ganciclovir

Back 36

Neutro, leuko and thrombocytopenia

Front 37

Anti-viral agents associated with Stephen Johnson syndrome

Back 37

Nevirapine, amprenavir

Front 38

HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism

Back 38

Protease inhibitors

Front 39

Antivirals that are teratogens

Back 39

Delavirdine, efavirenz, and ribavirin

Front 40

Antivirals associated with neutropenia

Back 40

Ganciclovir, zidovudine, saquinavir, and interferon

Front 41

HIV med used to reduce transmission during birth

Back 41

AZT (zidovudine)

Front 42

Drug used for African sleeping sickness

Back 42

Suramin

Front 43

Drug used in Chagas disease

Back 43

Nifurtimox

Front 44

Cephalosporins able to cross the BBB

Back 44

Cefuroxime (2nd) generation, Ceftazidime, Ceftriaxone

Front 45

Drug used for N. gonorrhea in females

Back 45

Ceftriaxone

Front 46

Cephalosporin causes kernicterus in neonates

Back 46

Ceftriaxone or cefuroxime

Front 47

SE of INH

Back 47

Peripheral neuritis and hepatitis

Front 48

Aminoglycoside that is least ototoxic

Back 48

Streptomycin

Front 49

Drug used in exoerythrocytic cycle of malaria

Back 49

Primaquine

Front 50

Drug of choice for leprosy

Back 50

Dapsone, rifampin and clofazimine combination

Front 51

DOC for herpes and its MOA

Back 51

Acyclovir; incorporated into viral DNA and chain termination

Front 52

Anti-microbials that cause hemolysis in G6PD-deficient patients

Back 52

Sulfonamides

Front 53

MOA of erythromycin

Back 53

Inhibition of protein synthesis at the 50s subunit of ribosome

Front 54

Anti-biotic frequently used for chronic UTI prophylaxis

Back 54

sulfamethoxazole/ trimethoprim

Front 55

Lactam that can be used in PCN allergic patients

Back 55

Aztreonam

Front 56

SE of imipenem

Back 56

Seizures

Front 57

Anti-viral with a dose limiting toxicity of pancreatitis

Back 57

Didanosine

Front 58

Oral antibiotic of choice for moderate inflammatory acne

Back 58

Minocycline

Front 59

Cephalosporins NOT able to cross the BBB

Back 59

Cefixime (3rd) generation