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59 Cards in this Set

  • Front
  • Back
MOA of quinolones
Inhibit DNA gyrase
MOA of penicillin
Block cell wall synthesis by inhibiting peptidoglycan cross-linkage
Drug used for MRSA
Vancomycin
Vancomycin MOA
Blocks peptidoglycan synthesis
Type of resistance found with vancomycin
Point mutation
Meningitis prophylaxis in exposed patients
Rifampin
Technique used to diagnose perianal itching, and the drug used to treat it
Scotch tape technique
and mebendazole
Two toxicities of aminoglycosides
nephro and ototoxicity
DOC for Legionnaires' disease
Erythromycin
MOA of sulfonamides
Inhibit dihydropteroate synthase
Penicillins active against penicillinase secreting bacteria
Methicillin, nafcillin, and dicloxacillin
Cheap wide spectrum antibiotic DOC of otitis media
Amoxicillin
Class of antibiotics that have 10% cross sensitivity with penicillins
Cephalosporins
PCN active against pseudomonas
Carbenicillin, piperacillin and ticarcillin
Antibiotic causing red-man syndrome, and prevention
Vancomycin, infusion
at a slow rate and antihistamines
Drug causes teeth discoloration
Tetracycline
MOA of tetracycline
Decreases protein synthesis by inhibiting 30S ribosome
Drug that causes gray baby syndrome and aplastic anemia
Chloramphenicol
Drug notorious for causing pseudomembranous colitis
Clindamycin
DOC for tx of pseudomembranous colitis
Metronidazole
Treatment of resistant pseudomembranous colitis
ORAL vancomycin
Anemia caused by trimethoprim
Megaloblastic anemia
Reason fluoroquinolones are contraindicated in children and pregnancy
Cartilage damage
DOC for giardia, bacterial vaginosis, pseudomembranous colitis, and trichomonas
Metronidazole
Treatment for TB patients (think RIPE)
Rifampin, Isoniazid, Pyrazinamide, and Ethambutol
Metronidazole SE if given with alcohol
Disulfiram-like reaction
Common side effect of Rifampin
Red urine discoloration
MOA of nystatin
Bind ergosterol in fungal cell membrane
Neurotoxicity with isoniazid (INH) prevented by
Administration of Vit. B6 (pyridoxine)
Toxicity of amphotericin
Nephrotoxicity
SE seen only in men with administration of ketoconazole
Gynecomastia
Topical DOC in impetigo
Topical mupirocin (Bactroban)
DOC for influenza A
Amantadine
DOC for RSV
Ribavirin
DOC for CMV retinitis
Ganciclovir
SE for ganciclovir
Neutro, leuko and thrombocytopenia
Anti-viral agents associated with Stephen Johnson syndrome
Nevirapine, amprenavir
HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism
Protease inhibitors
Antivirals that are teratogens
Delavirdine, efavirenz, and ribavirin
Antivirals associated with neutropenia
Ganciclovir, zidovudine, saquinavir, and interferon
HIV med used to reduce transmission during birth
AZT (zidovudine)
Drug used for African sleeping sickness
Suramin
Drug used in Chagas disease
Nifurtimox
Cephalosporins able to cross the BBB
Cefuroxime (2nd) generation, Ceftazidime, Ceftriaxone
Drug used for N. gonorrhea in females
Ceftriaxone
Cephalosporin causes kernicterus in neonates
Ceftriaxone or cefuroxime
SE of INH
Peripheral neuritis and hepatitis
Aminoglycoside that is least ototoxic
Streptomycin
Drug used in exoerythrocytic cycle of malaria
Primaquine
Drug of choice for leprosy
Dapsone, rifampin and clofazimine combination
DOC for herpes and its MOA
Acyclovir; incorporated into viral DNA and chain termination
Anti-microbials that cause hemolysis in G6PD-deficient patients
Sulfonamides
MOA of erythromycin
Inhibition of protein synthesis at the 50s subunit of ribosome
Anti-biotic frequently used for chronic UTI prophylaxis
sulfamethoxazole/ trimethoprim
Lactam that can be used in PCN allergic patients
Aztreonam
SE of imipenem
Seizures
Anti-viral with a dose limiting toxicity of pancreatitis
Didanosine
Oral antibiotic of choice for moderate inflammatory acne
Minocycline
Cephalosporins NOT able to cross the BBB
Cefixime (3rd) generation