Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/23

Click to flip

23 Cards in this Set

  • Front
  • Back
what's the MOA of TCAs?
inhibit reuptake of NorEpi and Serotonin
What are the side effects of TCAs?
Weight gain
Hepatic obstructive jaundice
Agranulocytosis
Toxic Psychosis
Seizures
Drowsiness
CNS stimulation(2nd amines)
Cardiac
What are the cardiac side effect of TCAs?
CHF
Heart block
Prolong QT interval
Hypotension
Tachycardia
Which TCA is most activating?
Most sedating?
Protriptyline (vivactil)
Doxepin (sinequan)-due to anticholinergic effects
Which TCA has the most cardiac side effects?
Amitriptyline(Elavil)-because it affects Norepi mostly, therefore, it will cause HTN and cardiac abnormalities
TCAs you can use for bedwetting?
Desipramine
Imipramine

Because of its anticholinergic effects
Which TCAs do you avoid in a pt with H/O seizures?
Maprotiline
Amoxapine
Clomipramine
What's an alternative to TCA if you're pt is obese?
SSRIs because they cause anorexia

TCA cause weight gain
What are the 3 monoamines in the brain?
serotonin
norepi
dopamine
Name the MAOIs Type A
Phenelzine (Nardil)-causes sedation
Tranylcypromine (parnate)-causes stimulation
Which MAOI is used in parkinson's
Selegiline- it increases dopamine
Give at low dose because high doses reduces its selectivity
Adverse effects of MAOIs
Sexual dysfunction
HTN crisis
Drug interactions
Which drugs do MAOIs interact with?
TCAs, SSRIs, Cocaine, Sudafed
what should you do before starting new meds and the pt is on a MAOI?
Need a two week wash-out
Name the SSRIs
Prozac
Zoloft
Paxil
LuVox
Celexa
Lexapro
Side effects of SSRIs
Wt loss/anorexia- abd effects
Insomnia
Sexual dysfunction
Sweating
Anxiety
What drug causes priapism, drowsiness, and orthostasis
Trazadone

Dose: 50-600 mg/d
What's the side effect of Venlafaxine?
Similar to SSRIs; high incidence of HTN
Wt loss
N/V
What is the MOA of Mirtazapine?
presynaptic alpha 2 antagonist, serotonin 2-3 receptor antagonist
what are the adverse effects of Mirtazapine?
dry mouth
wt gain
increase LFTs
sedation
VERY SADATING
What is the dose of Mirtazapine?
15-45mg/day at bed time
what drugs are used for OCD?
SSRIs and clomipramine
Lithium is last line
What is the dosing for OCD drugs?
Prozac 60-80 mg/d
Zoloft 100-200 mg/d
Paxil 40-60 mg/d
LuVox 100-300 mg/d
Benzo- use when >anxiety