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6 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Indomethacin
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Anti-inflammatory, analgesic, antipyretic
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Inhibits COX 1 and 2, and also PGE2 and phospholipase A2
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Allpurinol
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Uricosuric
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Inhibits xanthine oxidase by blocking molybdenum pterin center=>reduces production of uric acid
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Febuxostat
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Uricosuric
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Inhibits xanthine oxidase by blocking molybdenum pterin center=>reduces production of uric acid
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Colchicine
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Anti-inflammatory
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Arrests mitosis in metaphase by binding tubulin=>prevents mitotic spindle formation
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Probenacid
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Uricosuric, analgesic, anti-inflammatory
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Inhibition of uric acid reabsortion in PT=>binds to OAT=>increased excretion
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Sulfinpyrazone
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Uricosuric
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Inhibition of uric acid reabsorption in PT=>increased excretion
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