Pharm Cholinoreceptor-Activating & Cholinesterase-Inhibiting Drugs

Front 1

This agent has greater affinity for muscarinic receptors and used for postoperative and neurogenic ileus and urinary retention. And what is its MOA?

Back 1

Bethanechol--MOA is that it activates bowel and bladder smooth muscle

Front 2

Only direct acting agent that is very lipid soluble and used in glaucoma and Sjogren's syndrome. What is its MOA?

Back 2

Pilocarpine--MOA activates pupillary sphincter and ciliary muscle; stimulates salivation

Front 3

This agent used to treat dry mouth in Sjögren's syndrome

Back 3

Cevimeline

Front 4

Indirect-Acting ACh Agonist, alcohol, short DOA and used in diagnosis of myasthenia gravis and MOA

Back 4

Edrophonium. Neostigmine and pyridostigmine can also be use to treat MG. MOA--amplifies endogenous acetylcholine; useful effect at skeletal muscle neuromuscular end plates.

Front 5

Carbamate with intermediate action postoperative and neurogenic ileus and urinary retention and MOA

Back 5

Neostigmine--MOA-amplifies endogenous acetylcholine

Front 6

Treatment of atropine overdose and glaucoma (because lipid soluable). Enters the CNS rapidly and has a stimulant effect, which may lead to convulsions--and MOA

Back 6

Physostigmine--MOA-amplifies endogenous acetylcholine

Front 7

Treatment of myasthenia gravis--and MOA

Back 7

Pyridostigmine--MOA-amplifies endogenous acetylcholine

Front 8

Drug used for rapid reversal of nondepolarizing neuromuscular blockade in the diagnosis of myasthenia, and in differentiating myasthenic from cholinergic crisis. Also, administering this drug will improve muscle strength in myasthenic crisis but weaken it in cholinergic crisis.

Back 8

Edrophonium--also, the shortest-acting cholinesterase inhibitor

Front 9

Treatment of first choice due to toxicity from cholinomimetic drugs, such as parathion

Back 9

Atropine--an antimuscarinic agent

Front 10

Organophosphate and physostigmine overdose mnemonic

Back 10

DUMBBELSS: diarrhea, urination, miosis, bronchoconstriction, bradycardia, excitation (skeletal muscle and CNS), lacrimation, and salivation and sweating.

Front 11

Muscarinic agonist

Back 11

Muscarine, bethanechol, carbachol, pilocarpine

Front 12

Parathion toxicity can be reversed by?

Back 12

Pralidoxime

Front 13

Common toxicity from cholinesterase inhibitor?

Back 13

CNS depression or respiratory failure from neuromuscular paralysis

Front 14

Increased GI motility (abdominal surgery) can be occur from?

Back 14

Muscarinic cholinoceptor agonist

Front 15

Direct-acting cholinomimetic that is lipid soluble and used in the treatment of glaucoma and Sjogren's syndrome

Back 15

Pilocarpine

Front 16

An indirect-acting carbamate cholinomimetic with poor lipid solubility and duration of action of 2 - 4 h?

Back 16

Neostigmine

Front 17

Direct cholinomimetics

Back 17

acetylcholine, bethanechol, carbachol, pilocarpine, nicotine

Front 18

indirect-acting cholinomimetics

Back 18

edrophonium, neostigmine, physostigmine, pyridostigmine, echothiophate, parathion