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30 Cards in this Set
- Front
- Back
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Contraindications for using Cholinergics?
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Asthma,
Coronary Insufficiency hyperthyroid Peptic Disease, |
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Symptoms of muscarine poisoning?
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Lacrimation, Salivation, Bradycardia, Hypotension, headache, vision problems, bronchospasm
Shock |
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4 ACh agonists?
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Methacholine
Buthanechol Carbachol Pilocarpine (muscarinic) |
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Used to dx bronchial hyperactivity in asthma?
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Methacholine
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Used postop for abdominal surgery to dec distension/esophageal reflux?
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Buthanechol
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2nd choice for wide angle glaucoma?
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Carbachol
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Cholinergics not affected by acetylchoinesterase?
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Bethanechol
Carbachol |
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1st choice for wide angle glaucoma?
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Pilocarpine
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Tx of narrow angle glaucoma?
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Physiostigmine + Pilocarpine
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Types of cholinergic agonists?
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Indirect and Direct
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Types of indirect cholinergic agonists?
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Acetylcholinesterase antagonists either competative or substrate
Competative Antagonists: Edrophonium Donepezil Rivastigmine Tacrine Galantamine Substrates: Neostigmine Pyridostigmine Physostigmine Democurium |
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Used to dx myastenia gravis?
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Edrophonium
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#1 drug for Alzheimers?
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Donepezil, AChE inhibitor
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Tx for myasthenia gravis?
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Neostigmine
Physiostigmine |
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Tx for lost tone in GI/bladder?
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Neostigmine
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Duration of action of pyridostigmine, neostigmine, and democurium?
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Neostigmine<democurium<pyridostigmine
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3 classes of cholinergic antagonists?
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ANTI-MUSCARINICS:
Atropine Scopalamine Tolterodine/Oxybutinin Ipratropium Propantheline Tropicamide GANGLIONIC BLOCKERS: Depolarizing: Nicotine Non-depolarizing (work at nACh) Mecamylamine Tetraethylamonium NEUROMUSCULAR BLOCKERS: succinylcholine -curium |
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Anti-muscarinic used to treat COPD?
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Ipratropium (dec secretions)
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Used to relax GI when there is too much contraction/spasms
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Propantheline
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Used for overactive bladder?
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Oxybutynin/Tolterodine
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Used to reverse cholinergic toxicosis?
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Atropine (also for mydriasis and cycloplegia)
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Used in opthalmology to cause mydriasis (dilate) and cycloplegia (loss of accomadation)
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Tropicanamide
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Used for motion sickness, can cause drowsiness?
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Scopalamine
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Non-depolarizin ganglionic blocker used to treat HTN
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Mecamylamine
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Tx tourette's?
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Mecamylamine
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Two classes of neuromuscular blockers?
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depolarizing (succinylcholine)
non-depolarizing (-curium's) |
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Rapid onset neuromuscular blockers?
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succinycholine
rocuronium mivacurium all the others have slow onset |
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NMB's with short duration of action?
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Succinylcholine
Mivacurium |
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NMB's with int duration of action?
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Rocuronium
Vecuronium Cistatracurium Atracurium |
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NMB's with long duration of action?
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Pancuronium
Pipercuronium Doxacurium Metocurine Tubocurarine |
