Pharm Chapters 21-25, 57-58

Front 1

Protein derived hormones

Back 1

synthesized, stored and released into the bloodstream in response to a stimulus

Front 2

steroid hormones

Back 2

synthesized in the adrenal cortex and gonads from cholesterol, are released as they are synthesized

Front 3

Glucocorticoids

Back 3

cortisol
influence carb storage, has anti inflam effects, and increases protein catabolism

Front 4

mineralocorticoids

Back 4

aldosterone
regulates electolyte balance by promoting Na retention and K loss

Front 5

Thyroid Hormones

Back 5

T3 and T4
regulates the metabolic rate of the body and greatly influence growth and development

Front 6

Parathyroid Hormone

Back 6

PTH regulates calcium and phosphate metabolism

Front 7

Pancreatic Hormones

Back 7

Insulin and Glucagon
regulate the metabolism of glucose, lipids, and proteins

Front 8

Corticotropin releasing hormone or factor

Back 8

causes the release of corticotropin (ACTH) in response to stress and threating stimuli
effects corticosteroids

Front 9

Thyroid releasing hormone

Back 9

causes the release of TSH in response to stress, such as extreme cold

Front 10

Anterior pituitary

Back 10

synthesizes and secretes hormones

Front 11

Posterior Pituitary

Back 11

STores and releases hormones

Front 12

Growth hormone releasing hormone

Back 12

releases growth hormone
somatotropin

Front 13

growth hormone releasing inhibiting factor

Back 13

Somatostaian
inhibits release of GH

Front 14

Gondadotropin-releasing hormone

Back 14

affects FSH and LH

Front 15

Posterior pituitary hormones

Back 15

ADH
Oxytocin

Front 16

GH or somatotropin

Back 16

Stimulates growth of body tissues. it regulates cell division and protein synthesis required for normal and promotes an increase in muscle cells and lengthening of bone

Front 17

Which anterior pituitary hormones act directly on the target tissues

Back 17

GH and prolactin

Front 18

ADH or vasopressin

Back 18

functions to regulate water balance by make renal tube more permeable to water
this raises blood volume and arterial blood pressure

Front 19

oxytocin

Back 19

function in child birth and causes milk to come to the nipples

Front 20

Leuprolide (Lupron) is use for what

Back 20

Advanced prostatic cancer
Endometreosis
uterine fibroid tumors

Front 21

Lupron AE

Back 21

testosterone or estorgen deficiency like effects
increased bone pain
difficulty urinating
could agrivate deppresion

Front 22

Octreotide (sandostatin) indications

Back 22

Acromegaly
AIDS diarrhea

Front 23

How do you give lupron

Back 23

not orally b/c it is destroyed in the GI tract

Front 24

Indications for Somatropin

Back 24

children who's growth is impaired by a deficiency of endogenous hormones, chronic renal failure, turner's syndrome
only give it IM

Front 25

When is somatropin useless

Back 25

when the epiphyses of the long bone are closed

Front 26

Indications for desmopressin (DDAVP)

Back 26

diabetes insipidus, bedwetting, and hemostasis of bleeding (hemoplilia)

Front 27

Indications for VAsopressin

Back 27

bleeding esophageal varices caused by longterm portal hypertension

Front 28

Therapeutic effects of ADH drugs

Back 28

decreased urine output
increased sp gravity
decreased dehydration
decreased thirst

Front 29

AE of somatotropin

Back 29

mild edema, headache, muscle pain, weakness, and hyperglycemia

Front 30

AE of DDVAP

Back 30

headache, nasal congestion, nausea, and increased blood pressure. Serious water retention and hyponatreimia

Front 31

AE of Vassopressin

Back 31

water intox
chest pain
MI
inc blood pressure
abdominal cramps

Front 32

AE of octreotide (sandostation)

Back 32

dysrythmias, bradycarida, diarrhea, headache, hypergly, and gall stones

Front 33

drugs that inc effect of vasopressin

Back 33

general anestetics

Front 34

drugs that dec effect vasopressin

Back 34

lithium

Front 35

drugs that increase effect of oxytocin

Back 35

estrogens and vasoconstrictors (epi and norepi)

Front 36

When does corticosteroid negative feedback not work?

Back 36

during stress response b/c stress activates the SNS to produce more epi and norepi and the adrenal gland produces 10x the normal amount of cortisol

Front 37

Addison's disease

Back 37

primary adrenocortical insufficiency
destruction of the adrenal cortex TB, cancer, autoimmune disorders, prolonged steroid use; inadequate production of cortisol and alsosterone

Front 38

secondary adrenocortical insuficiency

Back 38

inadequate gluccocorticoids but mineralcorticoid ok

Front 39

what happens when the adrenal cortex is over functioning

Back 39

cushing disease